Mayo Clinic Cardiovascular CME

What Cardiologists Should Know About the Genetics of Thoracic Aortic Aneurysms

Guest: David Deyle, M.D.

Host: Kyle Klarich, M.D.

Thoracic aortic aneurysms can have an underlying genetic cause that affects patient management, surveillance, surgical decision-making, and family screening. In this episode, listeners will learn when to consider genetic testing and clinical genomics consultation for patients with thoracic aortic disease, including those with suspected Marfan syndrome, Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome, and other familial aortopathies. The discussion also explores how to interpret genetic test results and variants of uncertain significance, the importance of family history and clinical phenotype, and how a genetic diagnosis can guide surveillance and treatment decisions.

Topics discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

No CME credit offered for this episode.

Podcast episode transcript found here.

Recording date: 16-March-2026

Transcatheter Valve Interventions

Guest: Jared Bird, M.D.

Host: Malcolm Bell, M.D.

After listening to this podcast, listeners will be able to describe transcatheter treatment options for mitral valve disease, including transcatheter edge-to-edge repair (TEER) and transcatheter mitral valve replacement (TMVR); identify key echocardiographic and cardiac CT findings used for patient selection and procedural planning; and discuss the evolving role of transcatheter mitral valve interventions in the treatment of mitral regurgitation and other forms of mitral valve disease.

Topics discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

No CME credit offered for this episode.

Podcast episode transcript found here.

Recording date: 23-June-2026

Thoracic Aortic Aneurysm in Women

Guest: Thais Coutinho, M.D.

Host: Sharonne Hayes, M.D.

After listening to this podcast, listeners will be able to describe sex differences in the epidemiology and outcomes of thoracic aortic aneurysm (TAA), explain the biological and physiological factors that contribute to these differences, and identify clinically applicable strategies to improve TAA outcomes in both women and men.

Topics discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 02-February-2026

How AI Can Assist in the Performance of Point of Care Ultrasound

Guest: Jared Bird, M.D.

Host: Kyle Klarich, M.D.

Artificial intelligence is rapidly enhancing the performance of cardiac point-of-care ultrasound (POCUS) by improving image acquisition, providing easy-to-use tools for automated quantification, and reducing the impact of variability in user training on the acquisition of high-quality cardiac POCUS studies. AI-guidance solutions for obtaining high-yield cardiac POCUS views are helping both experienced clinicians and novice users acquire diagnostic-quality images for the rapid assessment of cardiac pathology. These AI tools serve as a powerful addition to the clinician's toolbox but do not replace comprehensive echocardiography or the expertise of trained healthcare providers.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 05-March-2026

Cardioneural Ablation in Practice: Cases, Curves, and Clinical Impact

Guest: Guru Kowlgi, M.B.B.S., M.S.

Host: Anthony Kashou, M.D.

In this episode of segment “ECG Making Waves” on Mayo Clinic podcast Interviews With the Experts, Dr. Anthony Kashou interviews Dr. Guru Kowlgi, a consultant in heart rhythm services at Mayo Clinic and assistant professor of medicine at the Mayo Clinic College of Medicine and Science. Listeners will hear a deep dive into real-world experience with cardioneural ablation, focusing on case volume, patient selection, and clinical outcomes.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 01-May-2026

Epidemiology of Myocarditis

Guest: Leslie Cooper, M.D.

Host: Sharonne Hayes, M.D.

Approximately 1,000,000 cases of myocarditis are diagnosed annually with an incidence of approximately 16/100,000.  The incidence is highest in men between 15 and 45 years of age.  However, after age 60 years, women have higher mortality than men. The overall mortality rate is 0.4/100,000.  The rates of diagnosis are double in high SDI regions compared to low STI regions, most likely due to the availability of the pivot all diagnostic tests, cardiac MRI and heart biopsy.  The incidence rates are stable while the death rates have decreased from 1990 to 2023.  Finally, the causes of myocarditis or changing with more cases of immune checkpoint inhibitor related myocarditis which can affect between 0.2 and 1.1% of patients receiving these cancer therapies.

Topics Discussed:

For more information, review the study below:

Klingel, K., Tschöpe, C., Yon, D.K. et al. Global epidemiology of myocarditis: disparities in age, sex and geography. Nat Rev Cardiol (2026). https://doi.org/10.1038/s41569-026-01276-w

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 01-April-2026

Chronic Total Occlusion

Guest: Abhiram Prasad, M.D.

Host: Paul Friedman, M.D.

Chronic total occlusions are frequently encountered and are associated with complex coronary artery disease and diffuse atherosclerosis. Percutaneous coronary intervention is a suitable option for relieving angina in select patients who remain symptomatic despite optimal medical therapy. Success rates of over 80% can be routinely achieved by CTO operators with MACE rates of less than 5%.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 14-April-2026

Tricuspid Repair and Replacement in the Cath Lab: A New Era

Guest: Mackram Eleid, M.D.

Host: Malcolm Bell, M.D.

In this episode of “Interviews With the Experts,” Mayo Clinic consultant in interventional cardiology Dr. Mackram Eleid explored the evolving landscape of transcatheter therapies for tricuspid valve disease. Listeners will hear an overview of current indications, benefits, and risks associated with transcatheter tricuspid repair and replacement. The discussion highlighted key factors that influence the choice between repair and replacement, reviewed current evidence, and examined important knowledge gaps and emerging data that may shape future clinical practice.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV 

LinkedIn: Mayo Clinic | LinkedIn

Cardiovascular Education App:

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 18-January-2026

Aortic Stenosis in the Younger Patient in 2026

Guest: Mackram Eleid, M.D.

Host: Malcolm Bell, M.D.

Dr. Malcolm Bell interviews Dr. Malcolm Eleid on the diagnosis and management of aortic stenosis in younger patients, as well as discussing patient-centered decision-making considerations for lifetime management of aortic stenosis. After review, listeners will understand current indications as well as advantages and disadvantages of transcatheter versus aortic valve replacement for younger patients with aortic stenosis. 

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 28-January-2026

What Cardiologists Should Know About Aortic Pathology

Guest: Melanie Bois, M.D.

Host: Malcom Bell, M.D.

Is all aortic disease the same?  In this episode, Dr. Melanie Bois reviews the major diagnostic categories of aortic disease and how they influence patient management, including surgical decision-making, surveillance, and genetic evaluation. The discussion involves the causes of heritable thoracic aortic aneurysms and highlights how pathology findings can provide important clues to underlying genetic syndromes. Finally, Dr. Bois outlines the spectrum of inflammatory aortic diseases and explore key differential diagnoses that help distinguish immune-mediated, infectious, and degenerative processes.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Recorded on: 28-January-2026