Clopidogrel Monotherapy in Chronic Coronary Artery Disease

Guest: Keri Zieminski, APRN, C.N.P., D.N.P.

Host: Sharonne Hayes, M.D.

This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of clopidogrel monotherapy in patients with chronic CAD that are not on anticoagulation. Discussion will include why there has been a shift towards redefining antiplatelet medical therapy for this patient population, brief overview of recent trials, and how to manage a patient on clopidogrel monotherapy that needs to undergo noncardiac surgery.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Global Practices in Cardiac Imaging for Cardiac Sarcoidosis

Guest: Tahir Kafil, M.D.

Host: Sharonne Hayes, M.D.

Cardiac imaging is a cornerstone in the diagnostic work-up and management of cardiac sarcoidosis. However, indications and use of advanced cardiac imaging vary from institution to institution, and even between providers at the same institution. We conducted an international Delphi consensus study of 89 global experts in cardiac sarcoidosis to evaluate real-world clinical practices and use of advanced cardiac imaging. We developed consensus for use of advanced cardiac imaging in cardiac sarcoidosis. Areas lacking consensus were noted as priority areas for research.

Topics Discussed:

The research study cited by Dr. Kafil was published on June 2, 2025. Click the following link to view the paper:

https://www.jacc.org/doi/full/10.1016/j.jcmg.2025.02.010

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Anticoagulation Monotherapy in Patients with Chronic Coronary Artery Disease and Atrial Fibrillation

Guest: Keri Zieminski, APRN, C.N.P., D.N.P.

Host: Sharonne Hayes, M.D.

This episode of Mayo Clinic’s “Interviews With the Experts” will give an overview of anticoagulation monotherapy in patients with chronic CAD and atrial fibrillation. Discussion will include a brief overview of recently published trials that highlight the use of anticoagulation monotherapy in chronic CAD with atrial fibrillation, and how to manage a patient on anticoagulation monotherapy that needs to undergo noncardiac surgery. 

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Updated Guidelines for Perioperative Cardiovascular Management for Noncardiac Surgery

Guest: Michael Cullen, M.D.

Host: Kyle Klarich, M.D.

This episode of Mayo Clinic’s “Interviews With the Experts” reviews the assessment of patients with known or suspected cardiovascular disease undergoing noncardiac surgery.  Dr. Michael Cullen discusses recommendations from 2024 ACC/AHA perioperative guidelines regarding medication management before and after noncardiac surgery, including recommendations for antiplatelet therapy and bridging anticoagulation.  Finally, he highlights new recommendations in the recent 2024 ACC/AHA perioperative guidelines and compare these guidelines to the 2022 European Society of Cardiology perioperative guidelines.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Obesity, Hypertension, and Risk Factors in Terms of Prevention and Decreasing the Risk of HfpEF

Guest: Affan Irfan, M.D., Ph.D.

Host: Stephen L. Kopecky, M.D.

HFpEF is a type of heart failure where the heart pumps normally but becomes stiff. This leads to fatigue, shortness of breath, and fluid retention. It is closely linked to obesity, hypertension, and metabolic disorders, with cases rising as these conditions become more common.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Aortic Regurgitation: Beyond the Valve

Guest: Vidhu Anand, M.B.B.S.

Host: Kyle Klarich, M.D.

In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Klarich and Dr. Anand discuss evolving approaches to assessing left ventricular remodeling in chronic aortic regurgitation. Dr. Vidhu Anand discusses research showing that LV volumes, global longitudinal strain, and myocardial fibrosis can detect dysfunction earlier than traditional guideline thresholds. Listeners can expect to better understand the role of multimodality imaging, extra valvular involvement, and practical steps echocardiographers can take to optimize AR assessment. 

Topics Discussed:

Please reference Dr. Anand's research article(s) here:

https://pubmed.ncbi.nlm.nih.gov/39545891/

https://pubmed.ncbi.nlm.nih.gov/33253815/

https://pubmed.ncbi.nlm.nih.gov/39218370/

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Presentation, Evaluation, and Management of Premature Ventricular Contractions

Guest: Alan M. Sugrue, M.B., B.Ch., B.A.O.

Host: Anthony H. Kashou, M.D.

In this episode, Dr. Anthony Kashou and Dr. Alan Sugrue cover a practical, evidence-based approach to premature ventricular contractions (PVCs), from incidental findings to high-burden, high-risk presentations. Listeners will gain tools to differentiate benign from pathologic PVCs, understand when to monitor versus refer, and recognize the role of catheter ablation in improving outcomes.

Topics Discussed:

LinkedIn: Mayo Clinic Cardiovascular Services

Podcast episode transcript found here.

Tricuspid Regurgitation: New Insights and Implications for Clinical Practice

Guest: Vidhu Anand, M.B.B.S.

Host: Kyle Klarich, M.D.

This episode of Mayo Clinic’s “Interviews With the Experts,” explores new insights into tricuspid regurgitation and its implications for clinical practice. Dr. Vidhu Anand discusses the dynamic nature of TR, its impact on prognosis, and the importance of close monitoring even when the condition appears to improve. The conversation highlights evolving guideline considerations, patient risk stratification, and how AI and machine learning may soon support earlier, more personalized interventions. Listeners will gain practical takeaways on when to escalate care and how to optimize long-term outcomes for TR patients.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Cardiovascular Diet Myths

Guest: Stephen Kopecky, M.D.

Host: Sharonne Hayes, M.D.

Since 2018, Trans-Fats are prohibited from being a food additive in the US. In this episode of “Interviews With the Experts,” Dr. Stephen Kopecky discussed how trans fats are still in our food, just not as much as pre-2018, and the main sources of trans fat are ultra-processed foods. Listeners will learn what foods scan raise your blood cholesterol (LDL-C) levels, increase heart attack risk, accelerate the aging process, and slow the aging process.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.

Evolving Treatment Landscape in Transthyretin Cardiac Amyloidosis

Guest: Rosalyn Adigun, M.D., Pharm.D.

Host: S. Allen Luis, M.B.B.S., Ph.D.

In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Allen Luis interviews Dr. Rosalyn Adigun on transthyretin cardiac amyloidosis. Listeners will come away with a detailed overview of the evolution of treatment options for patient diagnosed with transthyretin amyloid cardiomyopathy, highlighting historical perspectives, early registration studies, current treatment options, and an outlook on future directions in the management of transthyretin cardiac amyloidosis.

Topics Discussed:

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

No CME credit offered for this episode.

Podcast episode transcript found here.