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Choice of Anticoagulation
Guest: Ana Casanegra, M.D., M.S.
Host: Sharonne Hayes, M.D.
This podcast will equip clinicians with a practical, patient-centered framework for selecting anticoagulants across common cardiovascular and thrombotic conditions. Listeners will learn how to balance efficacy, bleeding risk, comorbidities, and patient preferences when choosing among DOACs, warfarin, and other options. Real-world considerations and common clinical pitfalls will be highlighted to support confident, evidence-based anticoagulation decisions in daily practice.
Topics Discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 07-April-2026
The Athlete’s Heart Paradox: Managing Arrythmias at Peak Performance
Guest: Guru Kowlgi, M.D.
Exercise is one of the best prescriptions for cardiovascular health—but can there be too much of a good thing? In highly trained athletes, years of intensive exercise can produce electrical, autonomic, and structural changes that may increase susceptibility to arrhythmias, while in other cases exercise may uncover an underlying cardiac condition. Dr. Guru Kowlgi discusses how clinicians can distinguish normal adaptations of the athlete’s heart from warning signs that warrant further evaluation, including exertional syncope, declining performance, and increasingly complex ventricular arrhythmias. He also explores individualized treatment strategies, from medications to catheter ablation, and the growing role of shared decision-making when determining whether an athlete can safely return to competition. Finally, the discussion puts sudden cardiac death in athletes into perspective and highlights the importance of both identifying those at increased risk and being prepared with CPR and rapid access to AEDs when unexpected cardiac arrest occurs.
Topics discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recording date: 30-September-2026
The Cardiovascular Risks of Recreational Adderall Use
Guest: Anna Svatikova, M.D., Ph.D.
Adderall has become a popular “study drug” and performance enhancer among college students and young professionals—but what happens to the cardiovascular system when someone without ADHD takes it recreationally? Dr. Anna Svatikova discusses research showing striking changes in blood pressure, heart rate, and sympathetic nervous system activity after just one dose in healthy, Adderall-naive adults. She and Dr. Paul Friedman explore what these findings could mean for palpitations, chest pain, arrhythmias, and other cardiovascular complications seen in young adults. They also explain why these results should not be confused with the risks of appropriately prescribed ADHD treatment and consider what may happen when Adderall is combined with energy drinks, alcohol, smoking, or underlying cardiovascular disease.
Topics discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recording date: 02-June-2026
What Cardiologists Should Know About the Genetics of Thoracic Aortic Aneurysms
Guest: David Deyle, M.D.
Host: Kyle Klarich, M.D.
Thoracic aortic aneurysms can have an underlying genetic cause that affects patient management, surveillance, surgical decision-making, and family screening. In this episode, listeners will learn when to consider genetic testing and clinical genomics consultation for patients with thoracic aortic disease, including those with suspected Marfan syndrome, Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome, and other familial aortopathies. The discussion also explores how to interpret genetic test results and variants of uncertain significance, the importance of family history and clinical phenotype, and how a genetic diagnosis can guide surveillance and treatment decisions.
Topics discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recording date: 16-March-2026
Transcatheter Valve Interventions
Guest: Jared Bird, M.D.
Host: Malcolm Bell, M.D.
After listening to this podcast, listeners will be able to describe transcatheter treatment options for mitral valve disease, including transcatheter edge-to-edge repair (TEER) and transcatheter mitral valve replacement (TMVR); identify key echocardiographic and cardiac CT findings used for patient selection and procedural planning; and discuss the evolving role of transcatheter mitral valve interventions in the treatment of mitral regurgitation and other forms of mitral valve disease.
Topics discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recording date: 23-June-2026
Thoracic Aortic Aneurysm in Women
Guest: Thais Coutinho, M.D.
Host: Sharonne Hayes, M.D.
After listening to this podcast, listeners will be able to describe sex differences in the epidemiology and outcomes of thoracic aortic aneurysm (TAA), explain the biological and physiological factors that contribute to these differences, and identify clinically applicable strategies to improve TAA outcomes in both women and men.
Topics discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 02-February-2026
How AI Can Assist in the Performance of Point of Care Ultrasound
Guest: Jared Bird, M.D.
Host: Kyle Klarich, M.D.
Artificial intelligence is rapidly enhancing the performance of cardiac point-of-care ultrasound (POCUS) by improving image acquisition, providing easy-to-use tools for automated quantification, and reducing the impact of variability in user training on the acquisition of high-quality cardiac POCUS studies. AI-guidance solutions for obtaining high-yield cardiac POCUS views are helping both experienced clinicians and novice users acquire diagnostic-quality images for the rapid assessment of cardiac pathology. These AI tools serve as a powerful addition to the clinician's toolbox but do not replace comprehensive echocardiography or the expertise of trained healthcare providers.
Topics Discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 05-March-2026
Cardioneural Ablation in Practice: Cases, Curves, and Clinical Impact
Guest: Guru Kowlgi, M.B.B.S., M.S.
Host: Anthony Kashou, M.D.
In this episode of segment “ECG Making Waves” on Mayo Clinic podcast Interviews With the Experts, Dr. Anthony Kashou interviews Dr. Guru Kowlgi, a consultant in heart rhythm services at Mayo Clinic and assistant professor of medicine at the Mayo Clinic College of Medicine and Science. Listeners will hear a deep dive into real-world experience with cardioneural ablation, focusing on case volume, patient selection, and clinical outcomes.
Topics Discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 01-May-2026
Epidemiology of Myocarditis
Guest: Leslie Cooper, M.D.
Host: Sharonne Hayes, M.D.
Approximately 1,000,000 cases of myocarditis are diagnosed annually with an incidence of approximately 16/100,000. The incidence is highest in men between 15 and 45 years of age. However, after age 60 years, women have higher mortality than men. The overall mortality rate is 0.4/100,000. The rates of diagnosis are double in high SDI regions compared to low STI regions, most likely due to the availability of the pivot all diagnostic tests, cardiac MRI and heart biopsy. The incidence rates are stable while the death rates have decreased from 1990 to 2023. Finally, the causes of myocarditis or changing with more cases of immune checkpoint inhibitor related myocarditis which can affect between 0.2 and 1.1% of patients receiving these cancer therapies.
Topics Discussed:
For more information, review the study below:
Klingel, K., Tschöpe, C., Yon, D.K. et al. Global epidemiology of myocarditis: disparities in age, sex and geography. Nat Rev Cardiol (2026). https://doi.org/10.1038/s41569-026-01276-w
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 01-April-2026
Chronic Total Occlusion
Guest: Abhiram Prasad, M.D.
Host: Paul Friedman, M.D.
Chronic total occlusions are frequently encountered and are associated with complex coronary artery disease and diffuse atherosclerosis. Percutaneous coronary intervention is a suitable option for relieving angina in select patients who remain symptomatic despite optimal medical therapy. Success rates of over 80% can be routinely achieved by CTO operators with MACE rates of less than 5%.
Topics Discussed:
Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on X: @MayoClinicCV
LinkedIn: Mayo Clinic | LinkedIn
No CME credit offered for this episode.
Podcast episode transcript found here.
Recorded on: 14-April-2026
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