This week’s View summarizes articles about the prevalence and clinical significance of aortic branch aneurysms in patients with Marfan syndrome, whether triglyceride levels are associated with subclinical atherosclerosis and vascular inflammation regardless of low-density lipoprotein cholesterol, and the clinical outcomes associated with the use of 4-factor prothrombin complex concentrates, idarucizumab, or andexanet alpha for reversal of severe direct oral anticoagulant-associated bleeding.