eanCast: Weekly Neurology

Moderator: Federica Agosta (Milan, Italy)

Guest: Philip van Damme (Leuven, Belgium) 

In this week’s episodes Federica Agosta hosts Philip van Damme as they discuss the new EAN Guideline on the Management of Amyotrophic Lateral Sclerosis. Find more information here.

EAN moderator: Youssuf Saleh (Oxford, United Kingdom)

Guest: Thanh Doan (Trondheim, Norway)

For this episodes Youssuf Saleh is joined by Thanh Doan as they discuss the role of brain circuits in neuroscience and how they can be used to advance both our understanding of disease and lay foundations for circuit-based treatments including neuromodulation.

EAN Moderator: Melinda Magyari (Copenhagen, Denmark)

Special Moderator: Brett Drummond (Melbourne, Australia)

Guest: Susana Otero (Barcelona, Spain)

In this episode eanCast: Weekly Neurology is joined by The ECTRIMS Podcast. Hosts Melinda Magyari and Brett Drummond talk about the ECTRIMS-EAN Vaccination Consensus Statement with lead author Susana Otero. Find the full article here.

Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Celia Oreja-Guevara (Madrid, Spain)

In this last August episode Melinda Magyari hosts Celia Oreja-Guevara as they explore the impact of MS on women's fertility, the shift in advice regarding pregnancy, and how pregnancy affects MS activity. They also discuss the importance of consulting a neurologist, considerations for artificial reproduction techniques, and recommendations for disease-modifying therapies, including treating relapses during pregnancy and breastfeeding.

Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Thomas Berger (Vienna, Austria)

Melinda Magyari and her guest Thomas Berger talk about how aging affects MS progression and management, focusing on immunosenescence's impact on the immune response and DMT effectiveness. They cover the rise of comorbidities in older MS patients, the challenges of using DMTs over age 55, the lack of clinical trials for this age group, and share lifestyle tips to improve quality of life and health outcomes.

Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Nikolaos Grigoriadis (Thessaloniki, Greece)

Melinda Magyari hosts Paolo Preziosa as they delve into the significance of central vein sign and chronic active lesions in multiple sclerosis diagnosis and prognosis. They explore how these MRI biomarkers enhance diagnostic accuracy and predict disease progression, emphasizing their potential clinical relevance and the need for further research to optimize MS treatment strategies.

Moderator: Melinda Magyari (Copenhagen, Denmark)

Guest: Nikolaos Grigoriadis (Thessaloniki, Greece)

Follow Melinda Magyari and her guest Nikolaos Grigoriadis in the first MS episode of this month as they explore the Epstein-Barr Virus and its potential link to multiple sclerosis. They discuss how EBV might trigger or worsen MS, the challenges in confirming this connection, and implications for treatment and prevention. Other MS risk factors, such as genetics, environment, vitamin D levels, and lifestyle, are also covered.

Moderator: Anne Pavy-Le Traon (Toulouse, France)

Guests: Giovanna Calandra-Buonaura (Bologna, Italy) and Valeria Iodice (London, United Kingdom) 

In this week’s podcast episode Anne Pavy-Le Traon hosts two guests, Giovanna Calandra Buonaura and Valeria Iodice, as they discuss a hot topic related to Phenoconversion in Pure Autonomic Failure (PAF). They highlight the natural history of PAF and the importance of recognising this disease as a possible prodromal/ premotor phase of other alpha synucleinopathies. They discuss novel clinical and multimodal biomarkers in early diagnosis of these disorders.

Moderator: Cristian Falup-Pecurariu (Brasov, Romania)

Guest: Valentina Leta (Milan, Italy)

In this episode, Cristian Falup-Pecurariu discusses with Valentina Leta the relationship between gastrointestinal dysfunction and movement disorders with a focus on Parkinson's disease. They explore the impact of gastrointestinal dysfunction as part of dysautonomia in people with Parkinson's disease, other neurodegenerative diseases, and the importance of identifying and managing these symptoms to improve their quality of life.

Moderator: Cristian Falup-Pecurariu (Brasov, Romania)

Guests: Alessandra Fanciulli (Innsbruck, Austria) and Roland Thijs (Heemstede, The Netherlands)

In this second episode of July, Cristian Falup-Pecurariu hosts Alessandra Fanciulli and Roland Thijs. They delve into the topic of Cardiovascular Autonomic Dysfunction and cover symptoms, diagnosis, and treatment of conditions like syncope and orthostatic hypotension, emphasizing their significance in neurodegenerative disorders and the importance of distinguishing these autonomic failures in clinical practice.