The Menopause and Cancer Podcast

Ep 127 - HRT and Local Oestrogen After Gynaecological Cancers


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In today’s episode, we discuss the use of hormone replacement therapy (HRT) and local oestrogen in all types of gynaecological cancer patients. Many women after ovarian, womb, cervical, vulval or vaginal cancers feel that they are left out of the conversation and research as so much emphasis is on the breast cancer community. So, here we are with a laser focus on menopause after gynae cancers and we hope this episode is helpful. 

We are joined by Mr. Vikram Talaulikar, an associate specialist at the reproductive medicine unit in University College London Hospitals NHS Foundation Trust and hon. associate professor at University College London.  

He explains that menopause after gynaecological cancer treatment is more challenging because it occurs suddenly and the symptoms are often more severe and persistent. 

We discuss the data and safety for the use of HRT and local oestrogen for:

1) Ovarian cancer

2) Endometrial cancer

3) Cervical cancer

4) Vaginal + Vulval cancer

Episode Highlights:

00:00 Intro.

13:05 HRT now considered for more cancer patients.

14:04 HRT generally safe for most ovarian tumours.

19:58 Prefer HRT after 12-24 months post-treatment.

22:09 Cervical cancer: treatment options hinge on type.

30:24 Post-surgery, vaginal oestrogen often necessary; discussions important.

33:32 Research non-hormonal treatments before using vaginal oestrogen.

38:39 Ideally see a menopause specialist early after cancer diagnosis.

42:34 Sarcomas contraindicate hormone use.

44:50 Holistic menopause care includes non-hormonal and local treatments.

49:18 Discuss options with GP, oncologist, or nurse specialist.


Connect with us:

For more information and resources visit our website: www.menopauseandcancer.org

Or follow us on Instagram @menopause_and_cancer

Join our Facebook group: www.facebook.com/groups/menopauseandcancerchathub


A big thanks to our trusted sponsor, The Better Menopause. I’m excited to share their amazing product, The Better Gut with you. Most women don’t realize that gut health and menopause symptoms are intrinsically linked—keeping your gut happy is the foundation for overall health, through all stages of life. The Better Gut is a daily capsule packed with a unique, science-backed probiotic blend designed to survive stomach acid, reach your gut alive and help improve symptoms such as bloating, hot flushes and anxiety. 

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The Menopause and Cancer PodcastBy Dani Binnington

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