Dr. Amanda Lund is an Associate Professor at the NYU Grossman School of Medicine. She discusses how the lymphatic vasculature serves as a critical and dynamic interface between tissues and the immune system, challenging the traditional view of lymphatics as passive conduits. She highlights how lymphatic vessels actively regulate immune responses by controlling fluid flow, antigen transport, and cell migration during infection and cancer, and explores their emerging roles in shaping immunity and tissue biology.

MHC I Shapes CD4 Immunity– MHC class I unexpectedly regulates CD4+ T cell cytotoxicity by protecting target cells from ferroptosis.

Re-Emergence of Oropouche Virus – Scientists have mapped the resurgence and long-term burden of Oropouche virus, revealing widespread infection across Latin America.

Scalable In Vivo T Cell Engineering – A new in vivo CRISPR-based system enables precise, stable generation of CAR T cells.

Gut–Brain Axis in Autoimmunity – Intestinal epithelial cells initiate autoimmune neuroinflammation via TH17 cell responses that migrate to the central nervous system.

Image courtesy of Dr. Amanda Lund.

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