Jim talks with James Fadiman and Jordan Gruber about the findings in their recent book Microdosing for Health, Healing, and Enhanced Performance. They discuss the definition of microdosing, "subthreshold" vs "subperceptual," typical doses, current usage statistics & demographics, its legal status & classification history, LSD, psilocybin, why cannabis isn't suitable for microdosing, mechanisms of action, dosing protocols, anti-inflammatory effects, health applications, enhancement applications, contraindications & side effects, research methodologies & limitations, commercial potential, global adoption patterns, and much more.

Episode Transcript

Microdosing for Health, Healing, and Enhanced Performance, by James Fadiman and Jordan Gruber

The Psychedelic Explorer's Guide, by James Fadiman

Our Symphony of Selves, by James Fadiman and Jordan Gruber

JRS EP126 - Jordan Gruber & James Fadiman on Our Symphony of Selves

Autism on Acid, by Aaron Paul Orsini

Institute of Noetic Sciences

James Fadiman, Ph.D., is a prominent figure in the field of psychedelic research, particularly known for his work on microdosing psychedelics like LSD and psilocybin. Often called the “father of microdosing,” Fadiman has a long history in the study of psychedelics dating back to the 1960s, when he worked on studies involving LSD and creativity while at Stanford University. After psychedelics were banned in the U.S., Fadiman shifted his focus but returned to psychedelic research decades later. His book, The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys, has become a key resource for safe psychedelic exploration. In recent years, he has pioneered research on microdosing, examining its potential benefits for mental health, cognitive enhancement, and overall well-being.

Jordan Gruber, JD, MA, founded the early online Enlightenment.Com community. After practicing law at Cooley Godward and focusing on IP law at NASA’s Moffett Field, as well as working at GNOSIS Magazine, Jordan became “the Practical Wordsmith,” a writer, ghostwriter, editor, and writing coach speciliazing in transformational modalities and practices. Jordan has helped create cutting-edge works on everything from forensic audio and financial services to health, wellness, psychology, and spirituality. Recent editing credits include Cindy Lou Golin’s The Shadow Playbook (2023), Scott Rogers’s The Mindful Law Student (2022), and Lawrence Ford’s The Secrets of the Seasons (2020).