In this episode, Dr. Mark Little shares his insights about genicular artery embolization (GAE), implications for patients with knee osteoarthritis, possible applications in other MSK interventions, and the importance of research for advancing the field. Dr. Little is a consultant diagnostic and interventional radiologist at Berkshire Imaging and Visiting Professor at the University of Reading in England.

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SYNPOSIS

The doctors also discuss challenges and considerations in patient selection, particularly concerning patients with comorbid peripheral arterial disease, and they further emphasize the need for high-quality research and collaboration within the IR community to continue improving MSK embolization practices.

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TIMESTAMPS

00:00 - Introduction

12:28 - Genicular Artery Embolization

24:30 - GENESIS 1 and 2 Studies

41:04 - Future of MSK Embolization

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RESOURCES

BackTable VI Episode 27 - Geniculate Artery Embolization for Osteoarthritis with Dr. Sandeep Bagla and Dr. Ari Isaacson:

https://www.backtable.com/shows/vi/podcasts/27/geniculate-artery-embolization-for-osteoarthritis

BackTable VI Episode 85 - Genicular Artery Embolization for OA with Dr. Jafar Golzarian:

https://www.backtable.com/shows/vi/podcasts/85/genicular-artery-embolization-for-oa

GEST MSK Annual Meeting:

https://thegestgroup.com/annual-msk-meeting/

GENESIS 1 - Genicular artEry embolizatioN in patiEnts with oSteoarthrItiS of the Knee (GENESIS) Using Permanent Microspheres: Interim Analysis:

https://pubmed.ncbi.nlm.nih.gov/33474601/

GENESIS 2 - Genicular Artery Embolisation in Patients with Osteoarthritis of the Knee (GENESIS 2): Protocol for a Double-Blind Randomised Sham-Controlled Trial:

https://pubmed.ncbi.nlm.nih.gov/37337060/

Dr. Little Genicular Artery Anatomy Paper - Cadaveric and Angiographic Anatomical Considerations in the Genicular Arterial System: Implications for Genicular Artery Embolisation in Patients with Knee Osteoarthritis:

https://pubmed.ncbi.nlm.nih.gov/34657976/

Dr. Sid Padia’s Knee OA Research (UCLA) - Genicular Artery Embolization for the Treatment of Symptomatic Knee Osteoarthritis:

https://pubmed.ncbi.nlm.nih.gov/34703964/

Dr. Lars Lönn from Copenhagen Trial - Genicular Artery Embolization as Pain Treatment of Knee Osteoarthritis (GETKO):

https://classic.clinicaltrials.gov/ct2/show/NCT05360329

Dr. Anna Martinez from Spain Shoulder Study - Mid-Term Results of Transcatheter Arterial Embolization for Adhesive Capsulitis Resistant to Conservative Treatment:

https://pubmed.ncbi.nlm.nih.gov/33135118/

Dr. Anna Martinez from Spain Shoulder Study - Clinical Outcomes of Transcatheter Arterial Embolization for Secondary Stiff Shoulder:

https://pubmed.ncbi.nlm.nih.gov/33478903/