How has Laser Atherectomy advanced over the years to treat patients with coronary and peripheral artery disease? Dr. On Topaz, renowned specialist in laser atherectomy, answers exactly that and much more in this week’s episode the BackTable Podcast. Dr. Topaz is an interventional cardiologist and a professor of medicine at Duke University.

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SYNPOSIS

The doctors begin their discussion by comparing traditional Excimer laser and new Auryon laser technologies. The conversation also covers thrombus management, use of lasers in complex plaques, the latest research studies on laser atherectomy, and future developments in laser technology for varied medical applications.

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TIMESTAMPS

00:00 - Introduction

10:01 - Laser Atherectomy & Thrombus Management

21:59 - Laser Applications in Peripheral Arterial Disease

28:12 - Laser in Interventional Cardiology

41:17 - New Laser Technologies

47:50 - Research Findings and Clinical Trials

59:09 - Future Prospects and Applications

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RESOURCES

Book by Dr. On Topaz - Debulking in Cardiovascular Interventions and Revascularization Strategies:

https://www.sciencedirect.com/book/9780128214510/debulking-in-cardiovascular-interventions-and-revascularization-strategies

Book by Dr. On Topaz - Lasers in Cardiovascular Interventions:

https://link.springer.com/content/pdf/10.1007/978-1-4471-5220-0.pdf

Book by Dr. On Topaz - Cardiovascular Thrombus: From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions:

https://www.sciencedirect.com/book/9780128126158/cardiovascular-thrombus

Paper from Dr. Giancarlo Biamino - The excimer laser: science fiction fantasy or practical tool?:

https://pubmed.ncbi.nlm.nih.gov/15760264/

Clinical Trial from Dr. John Bittl - Predictors of outcome of percutaneous excimer laser coronary angioplasty of saphenous vein bypass graft lesions. The Percutaneous Excimer Laser Coronary Angioplasty Registry:

https://pubmed.ncbi.nlm.nih.gov/8023778/

Paper from Dr. Warren S. Grundfest - https://journals.lww.com/coronary-artery/citation/1990/07000/laser_angioplasty.4.aspx

Paper from Dr. George S. Abela - Abrupt Closure After Pulsed Laser Angioplasty: Spasm or A “Mille-Feuilles” Effect?:

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1540-8183.1992.tb00830.x

Solid state, pulsed-wave 355 nm UV laser atherectomy debulking in the treatment of infrainguinal peripheral arterial disease: The Pathfinder Registry:

https://pubmed.ncbi.nlm.nih.gov/38566525/