The Reflux Revolution Podcast by Molly Pelletier

Ep. 9: Is Histamine Causing Your Acid Reflux? | GERD, MCAS & Low Stomach Acid Explained


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If you’ve been told reflux is just “too much acid” or feel like you’ve tried everything without relief, this episode is for you.


We’re joined by Dr. Zachary Spiritos, a Duke-trained gastroenterologist who specializes in neurogastroenterology and functional GI care, to unpack the real root causes of reflux—from structural issues to overlooked contributors like POTS, MCAS, and hypermobility.


🎙 About Dr. Spiritos: Originally from Philadelphia, Dr. Spiritos now practices in North Carolina. He completed his gastroenterology fellowship at Duke University and focuses on IBS, dysautonomia, functional GI disorders, and complex motility issues. He integrates nutrition, stress management, and gut-brain therapies to support whole-person healing.


🎯 What You’ll Learn in Episode 9:

• Why abdominal pressure—not just acid—is a major reflux driver

• The truth about low stomach acid (and what testing actually shows)

• The impact of hiatal hernias, POTS, MCAS, and hypermobility

• Why diet-only approaches often fall short

• A full-body approach to healing reflux symptoms


💛 If this episode opened your eyes, leave a review, follow the show, and share it with someone who needs real answers. Healing starts with understanding.


🌿 Resources & Support:

 • Dr. Zachary Spiritos: Instagram: @drzacspiritos

• Explore coaching & resources: www.flora-nutrition.com

• Follow on Instagram: @mollypelletier.rd

• Watch on YouTube: Molly Pelletier, RD

• Follow on TikTok: @mollypelletier.RD

• Apply for 1-on-1 coaching with FLORA Nutrition → https://www.mollypelletier.com/nutritioncounselingapplication


FREE 14 Day Reflux Reset Program: https://calm-queen-816.myflodesk.com/wffw6xiefw

FREE 3 day Acid Reflux Meal Plan : https://calm-queen-816.myflodesk.com/js99xqtzdn

Disclaimer: This podcast is for educational purposes only and not a substitute for personalized medical advice. Always consult your healthcare team before making changes to your routine.


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The Reflux Revolution Podcast by Molly PelletierBy Molly Pelletier, MS, RD | FLORA Nutrition

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