The Whole View with Stacy Toth

Episode 289: Food Allergy, Sensitivity, and Intolerance: What’s the Difference?


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Ep. 289: Food Allergy, Sensitivity, and Intolerance: What's the Difference?


In this episode, Stacy and Sarah each had severe allergic reactions. Inspired by those experiences, they break down the differences between allergies, intolerances and sensitivities and why you might not get the correct information from allergy tests.


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The Paleo View (TPV), Episode 289: Food Allergy, Sensitivity, and Intolerance: What's the Difference?
  • Intro (0:00)

  • News and Views (0:40)
    • It's been an interesting week for both Stacy and Sarah.
    • Last week Stacy had an anaphylactic shock to gluten.
    • This was the first time this happened to Stacy.

  • Stacy's mom has this, and Stacy was hoping she wouldn't develop it.

  • She assumed something was gluten-free and didn't read the ingredients.


  • Sarah was exposed to a Sulfa medication, which she is highly allergic to.
    • She was nearly hospitalized and still recovering after a week.

  • It was one of the biggest health crisis she has experienced, and very scary.

  • She won't be able to participate in the Cross-fit open because of it.


  • This is a common experience - what life with autoimmune disease, food sensitivity, chronic illness is.

  • Stacy's reaction to things she is sensitive to is much less than it was years ago.
    • She attributes this to improved gut health.

  • She had no intestinal symptoms after being exposed to gluten recently.
    • This was the most gluten she had been exposed to in over 8 years.

  • Stacy was told in the allergist's office that she did not have a gluten allergy.

  • The receptionist at the office was excited that Stacy "could eat gluten!"





  • Science with Sarah: The difference between a food allergy, sensitivity, and intolerance. (13;28)
    • Allergy vs. Intolerance
    • Both reactions are mediated by antibodies being produced against an antigen in the food.

  • The difference is in the type of antibodies that are produced.
    • Allergies are mediated by IgE antibodies.
    • Trigger the released of histamine from mast cells and basophils.

  • This is a very fast working system, usually a fast reaction.

  • Symptoms are caused by the release of histamine.
    • Hives, rashes, swelling of tissues of the face, red skin, sneezing, coughing, red eyes, heart racing, GI symptoms, shortness of breath, etc.

  • Anaphylaxis is a very severe, life threatening reaction characterized by hives, swelling, trouble breathing, and going into shock.

  • Seasonal allergies are also caused by the released of histamine, but usually are less severe.


  • Skin allergy testing is typically done in one of two ways.
    • 1. By placing a drop of concentra
    ...more
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