How do we square genetically influenced mental disorders with the theory of explanatory universality?

In a previous episode, Tracy asked Bruce how to reconcile her experience with mental disorders, like narcissism, with the idea of Universal Explainers. This is part 2 of that discussion.

In the last episode, Bruce introduced the idea that emotions and feelings aren't the same as ideas and go back to an earlier point in our evolutionary history. The genes then use our feelings to try to coerce us or encourage us via pleasures and pain. 

Bruce completes his list of possible ways genes can affect our personality and ideas without violating universality:

In addition, we discuss how the existence of insanity, dreams, and people who are extremely mentally challenged prove that there is such a thing as a person that is not a universal explainer but can still reason to a degree. See Steven Peck's "My Madness" for an amazing example.

Then we introduce the strongest problem we currently know of: the extreme heritability of psychopathy in some children.