Bradyarrhythmia during AF screening, thrombolysis in stroke, NP vs MD care, and the most biased paper this year — on LAAO — are the topics John Mandrola, MD, discusses in this week’s podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit: https://www.medscape.com/twic

I. Screening with ILR

- Ade Adamson Tweet https://twitter.com/AdeAdamson/status/1625878856820482048?s=20

- The Rapid Rise in Cutaneous Melanoma Diagnoses

https://www.nejm.org/doi/full/10.1056/NEJMsb2019760

- Loop Trial https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01698-6/fulltext

- Prevalence and Prognostic Significance of Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care https://jamanetwork.com/journals/jamacardiology/fullarticle/2801362

II. Thrombolysis in Mild Stroke

Thrombolysis Not Necessary in Mild Nondisabling Stroke: ARAMIS

https://www.medscape.com/viewarticle/988381

- PRISMS Trial https://jamanetwork.com/journals/jama/fullarticle/2687354

- Risk of selection bias assessment in the NINDS rt-PA stroke study https://pubmed.ncbi.nlm.nih.gov/35705913/

- Tissue Plasminogen Activator for Acute Ischemic Stroke https://www.nejm.org/doi/full/10.1056/NEJM199512143332401

- Effects of alteplase for acute stroke; Hacke et al meta-analysis https://journals.sagepub.com/doi/10.1177/1747493017744464

- Methodological survey of missing outcome data in an alteplase for ischemic stroke meta-analysis

https://onlinelibrary.wiley.com/doi/full/10.1111/ane.13656

- ECASS; Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke https://www.nejm.org/doi/full/10.1056/nejmoa0804656

- Thrombolysis with alteplase 3-4.5 hours after acute ischaemic stroke: trial reanalysis adjusted for baseline imbalances https://pubmed.ncbi.nlm.nih.gov/32430395/

III. NP vs MD Care

This Doc Still Supports NP/PA Led Care ... With Caveats https://www.medscape.com/viewarticle/967073

- The Productivity of Professions: Evidence from the Emergency Department https://www.nber.org/papers/w30608

- Independent Nurse Practitioners and Physician Assistants: A Doc's View https://www.medscape.com/viewarticle/924047

IV. LAAO vs OAC

- Comparative Effectiveness of Left Atrial Appendage Occlusio Versus Oral Anticoagulation by Sex

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062765

You may also like:

Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

https://www.medscape.com/features/public/machine

The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD.

https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact [email protected]