The Filtrate

Joel Topf

Swapnil Hiremath

AC Gomez

Jordy Cohen

Nayan Arora

Special Guest

Brendon Nuen

Editing by

Simon Topf and Nayan Arora

Show Notes

FINEARTS-HF in NEJM

FINEARTS Kidney outcomes in JACC

FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes in Nature Medicine discussion in NephJC

BARACH-D: Low-dose spironolactone and cardiovascular outcomes in moderate stage chronic kidney disease: a randomized controlled trial (Nature Medicine)

Live Freely Filtered at KidneyWk

Swapnil comes out as a SpiroStan post to NephJC

TOPCAT

TOPCAT primary publication

TOPCAT North American results

TOPCAT funny business explained

AHA/ACC/HFSA Heart Failure Guidelines (PDF)

SGLT2i are 2a

MRA are a 2b

ARBs are a 2b

ARNI are a 2b

Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction: Detailed Phenotypes, Prognosis, and Response to Spironolactone

Kansas city cardiomyopathy questionnaire in patients with CKD without a diagnosis of heart failure: https://pubmed.ncbi.nlm.nih.gov/21187260/

GFR slope with steroidal MRAs in HF: https://onlinelibrary.wiley.com/doi/10.1002/ejhf.2635

Why Has it Been Challenging to Modify Kidney Disease Progression in Patients With Heart Failure? (JACC)

Tubular Secretions

Swap: Disclaimer on Apple TV

AC: Duo Lingo Plushy (Amazon)

Nayan: The Puzzle Box

Jordy: Project Hail Mary

Brendon has a podcast, The Kidney Compass with Shikha Wadhwani. And he recommends singer-songwriter, Maggie Rogers (YouTube)

Joel: The Singularity Is Nearer: When We Merge with AI by Ray Kurzweil

Closing music, Tim Yau with The Kidney Connection