Drake Toll's family is going through a serious, brutal health crisis with his brother Landon, the kindest human you've ever met. If you have any information, please share this video and comment below. If not, please keep us in your thoughts and prayers. PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) are debilitating conditions characterized by a sudden and dramatic onset of neurological and psychiatric symptoms in children. PANDAS is the more specific and established term, referring to a subtype of PANS where the symptoms are triggered specifically by a Group A Streptococcus (strep) infection, such as strep throat. It is hypothesized to be an autoimmune reaction where the body's immune system, in fighting the strep bacteria, mistakenly creates antibodies that attack the basal ganglia—a region of the brain involved in motor control, emotion, and behavior. PANS is the broader umbrella diagnosis, used when a child experiences the same acute, severe onset of symptoms but the trigger is not definitively a strep infection. PANS has been linked to other infections (like flu or Lyme disease), immune system issues, or environmental factors. The defining characteristic of both disorders is the acute onset—the symptoms "explode" in severity, often reaching full intensity within 24 to 48 hours, leaving parents feeling as though they've "lost their child." Core Symptoms and Treatment The symptoms are wide-ranging and fall into three main criteria for diagnosis: Sudden, severe onset of Obsessive-Compulsive Disorder (OCD) or severely restricted food intake. Concurrent, abrupt onset of at least two other severe neuropsychiatric symptoms, which can include severe separation anxiety, motor or vocal tics, emotional lability (extreme mood swings and rage), behavioral regression, and sudden deterioration in school performance. Symptoms are not better explained by a known medical or neurological disorder. Treatment typically employs a three-pronged approach: treating the underlying infection with antimicrobials (such as antibiotics for PANDAS), managing the inflammation and immune system dysfunction with anti-inflammatory drugs or, in severe cases, immunomodulatory therapies like IVIG, and providing psychological support with Cognitive Behavioral Therapy (CBT) to manage the OCD and anxiety symptoms. Early and comprehensive intervention is crucial. Follow & Subscribe on all Podcast platforms… 🎧 https://link.chtbl.com/LOBig12?sid=YouTube Locked On College Conferences, HBCU, Basketball & More 🎧 https://linktr.ee/LockedOnCollege Follow on Twitter: https://twitter.com/drakectoll Follow the show on Twitter: https://twitter.com/LOBig12

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