Jim Goetz and Dr. Mike Brandon of Functionised discuss the in's and out's of body fat, why you gain it, whats good about it, what's bad about it and how to remove excess.
Woes of Fat
Define fat- adipose, so body fat%, not bmi!
Speaking white adipose here, not brown
For men, a percentage of body fat greater than 25% defines obesity, with 21-25% being borderline. For women, over 33% defines obesity, with 31-33% being borderline.
-other than being ugly, we get told to lose it, but why?
Just to buy new clothes
Physical
Excess weight on joints, back, neck
More difficult for correct posture which leads to more pain
Hormones it effects- why they matter
Leptin
suppress hunger, when depleted increases obesity- Where does it come from/why does it stop
Injections dont help. Ceiling for it and brain becomes resistant to it Does not increase leptin by decreasing food intake; rather, lack of leptin acts as a signal to increase food intake Obesity decreases sensitivity to it, so DM and obese have a harder time feeling full
Aromatase- is released
Converts test to estrogen- decreases metabolism, increases insulin resistance
High estrogen issues
Females- Homronal acne, depressed metabolism,irregular menstration, bloating, cold/itchy hands/feet, insomnia, headaches, low sex drive, increased breast and other cancer risks
Males- gynecamastia, low sex drive, Erectile dsfunction, infertilaty
Resistin- also released by epithelial cells, increased secretion with a high body fat percentage
Directly increases insulin resistance-
Increases production of LDL cholesterol
Increases cardio vascular disease risk
Appears that centralised/wastline adipose releases more than other locations
Association with DMtype 2 and centralised obesity faster than booty fat
Pro inflammatides- mainly from resistin
Interlukin 1, 3, 6; tumor necrosis factor-
Causes systemic long term inflammation, like food sensitivities too
Inflammation basis for …
Increases risk of rheumatoid conditions
Neuro transmitters
Serotonin is released with insulin secretion, mainly from carb diet which is VERY common in obesity.
“Use too much” serotonin and we get a little depressed, eat more sugar to increase mood, becomes less effective so do more frequently
Part of the addiction cycle of carby foods
Leads to many more poor choices when depressed
Serotonin and dopamine
Decreased transporters, so it gets harder to use these happy hormones/endorphions
Comorbidities- things that are increased risk and caused by or in part by obesity
Heart disease
DM- resistin, and poor life style habits
Cancer- hormonal cancers more so, but increased of all cancers since others are inflammatory
Stroke - better chance surviving it...but also getting it
Homron imbalances- stated above
GI issues - inflammation of bowel, and then colon cancer,
Dementia-
Healing time?
Depression- serotonin burn out
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