In this episode, Dr. Jeremy Pettus and Dr. Steve Edelman go head-to-head in a friendly face-off between two of the most talked-about medications in diabetes and weight management: Ozempic and Mounjaro. Both are part of the powerful GLP-1 class, but which one might be better for you? From A1C reduction and weight loss to heart and kidney protection, ease of use, side effects, and insurance coverage—Drs. E & P walk you through a category-by-category comparison. They bring the clinical data and their own real-world patient experience to help you understand the key differences (and similarities) between these leading therapies. Whether you're managing type 2 diabetes, living with type 1, or exploring options for weight loss, this episode is designed to help you make an informed decision with your healthcare provider.

Key Topics:

• How These Medications Work: Learn the difference between GLP-1 and dual agonist therapies
• A1C Reduction: See which drug leads to greater blood sugar improvements based on head-to-head clinical trials.
• Weight Loss: Discover how much weight patients lose on each medication—and why Mounjaro often shows stronger results.
• Heart Health: Understand which medication has FDA approval for cardiovascular protection and what’s still under investigation.
• Kidney Protection: Explore the latest studies showing Ozempic’s ability to slow kidney disease progression.
• Side Effects: Get practical tips on managing common GI side effects and why titration matters.
• Ease of Use: Compare how the pens work, dosing flexibility, and what may be easier for patients day to day.
• Sleep Apnea: Find out how Mounjaro earned a new indication for reducing sleep apnea severity—especially through weight loss.
• Access for Type 1s: Learn why these meds aren’t yet approved for T1D and how some patients are still getting them.
• Emerging Indications: Hear about new uses for these meds, including fatty liver, osteoarthritis, and even alcohol reduction.
• How to Choose: Get expert guidance on which medication may be right for you based on your goals and health needs.