Oregon and USC face off in a high-stakes battle where injuries threaten both teams’ College Football Playoff hopes. Quarterbacks Dante Moore and Jayden Maiava headline the clash, but depleted receiving corps and backfields add uncertainty. Can Oregon’s top-ranked Big Ten passing defense contain Maiava  and USC’s explosive offense, or will the Trojans’ resilient freshman King Miller fuel a surprise upset?

Craig Shemon spotlights Oregon’s deep running back room, USC’s injury updates—including Waymond Jordan’s absence—and the impact of missing playmakers. The episode reviews recent games, keys to victory, and the lingering Pac-12 rivalry that intensifies the matchup. Additional coverage includes James Franklin’s move to Virginia Tech, Nebraska’s quarterback situation, and updates from around the Big Ten. The playoff race, critical injuries, and legacy-defining moments are all on the line—who will seize the opportunity?

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