Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Hashem El-Serag from the Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA, on the paper "Serum biomarker signature is predictive of the risk of hepatocellular cancer in patients with cirrhosis" published in paper copy in Gut in June 2024.