Dr. Sam Shay joins to explore the intricate relationship between genetics, diet, and migraines. The episode delves into the AMY1 gene's role in carbohydrate tolerance and its link to migraine triggers, as well as the connection between histamines, inflammation, gluten sensitivity, and headaches. Genetic factors in weight gain and inflammation are examined, emphasizing the importance of addressing root causes and prioritizing interventions through genetic insights.

(0:00) Introduction to Dr. Sam Shea and the role of genetics in diet and migraines

(1:11) Emotional, cultural, and genetic factors in diet

(2:12) Challenges and advancements in genetic testing for health

(3:20) The AMY1 gene, carbohydrate tolerance, and migraine triggers

(6:16) Understanding histamines, inflammation, and headache connections

(8:06) The impact of genetics on gluten sensitivity and migraines

(9:19) Histamine's evolutionary role and its effects on headaches

(11:58) Genetic factors in different types of weight gain and inflammation

(14:47) The role of medication and the need for addressing root causes

(19:30) Delving into the APOA2 gene

(23:20) Strategies for prioritizing interventions based on genetics

(27:02) Closing remarks and future topics