Could inflammation and the blood-brain barrier help explain why some seizures remain uncontrolled? Prof. Colin Doherty discusses emerging research into immune activity in epilepsy, how steroids may temporarily improve seizure control, and why future immunotherapies could help some people whose seizures do not respond to current treatments.

Chapters 📖
00:00 Trailer & intro
00:31 Precision therapy for autoimmune diseases
01:27 Hypothesis: could steroids prevent seizures through mending the leakage of the Blood Brain Barrier?
03:53 Neurologists and researchers need to think about autoimmune
04:57 Blood Brain Barrier, steroids and genetics - current study
07:01 History: why haven’t we done this research already?
08:13 Immunologists: work with us!
09:48 Comparison: cancer and immunology
12:08 Clinicians and scientists: work with us!
13:51 People with an epilepsy and carers: work with us!
15:27 Closing thoughts & thanks

🔗 Episode page and transcript epilepsy-sparks-insights/autoimmune-therapy-blood-brain-barrier

🌐 More about Colin epilepsysparks.com/guests/colin-doherty

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