Karen addresses the troubling rise in early-onset cancers among adults under 50, particularly women. Drawing on the latest research, she discusses contributing factors—from delayed screenings and family history to gut health, environmental exposures, and systemic inflammation. Karen also highlights how current healthcare gaps, lifestyle factors, and even prenatal influences may be playing a role in this growing health crisis.

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Karen welcomes Donna White, a leading expert in bioidentical hormone replacement therapy (BHRT) with over 30 years of experience. They discuss the myths and truths about hormone therapy, the critical role of proper testing and individualized treatment plans, and how BHRT can drastically improve quality of life for women in menopause and beyond. Donna shares her personal journey with hormonal imbalance, her mission to train providers across the country, and practical advice for finding a knowledgeable, well-trained BHRT provider.

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Karen unpacks the surprising connection between hormones and the human voice—especially for singers. Drawing from her dual background in opera and medicine, she explains how hormonal shifts throughout the menstrual cycle can impact vocal quality, flexibility, and range.

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Karen shares how a friend's breast cancer diagnosis became a powerful example of self-advocacy in action. From discovering she didn’t need chemotherapy after requesting additional testing, to researching scalp cooling treatments and skin protection during radiation, this story highlights how knowledge and persistence can lead to better care. 

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Karen shares a powerful listener story about self-advocacy in healthcare and how trusting your instincts can be lifesaving. After experiencing persistent symptoms that were initially dismissed by a doctor, this listener took charge of her health, sought a second opinion, and ultimately discovered a serious diagnosis.

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Karen continues her discussion on HPV, focusing on the types of cancers it can cause and the best prevention methods. She breaks down the staggering statistics on HPV-related cancers, explains why the virus can remain dormant for decades, and highlights the importance of screening and early detection.

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Karen unpacks the risks of HPV for women in their perimenopausal and menopausal years. She explains how the virus spreads, why it can re-emerge decades after initial exposure, and how hormonal and immune system changes impact its persistence.

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Karen explores the importance of iodine and how its deficiency can impact overall health. She discusses the essential role iodine plays in thyroid function, metabolism, and cognitive development, particularly in pregnant women. Karen explains why iodine deficiency is on the rise, how to test for it, and the best ways to ensure adequate intake through diet and supplements.

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Karen explores the potential of UTI vaccines as an alternative to antibiotics for treating recurrent urinary tract infections. She explains how UTIs develop, why traditional antibiotic treatments often fail, and how vaccines work to boost the body's immune response.

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Karen examines the use of kava supplements, exploring their potential benefits for anxiety and their serious risks, including liver toxicity. She highlights key studies on kava's effectiveness, explains its traditional use, and warns of its interactions with medications. She also shares a list of alternative supplements that have been shown to help with anxiety and depression without the significant risks associated with kava. 

Visit our website itchyandbitchy.com to read blog posts on the many topics we have covered on the show.