The United States is the most prosperous and advanced nation in the history of humanity—but it's currently facing a crisis of happiness. What went wrong?

Arthur Brooks, Harvard professor, best-selling author, and renowned social scientist, has dedicated himself to tackling America's satisfaction deficit, and in this episode, he reveals his four keys to authentic happiness. (Not on the list: riches, power, or fame). Tempted to make a bucket list to get as much as possible out of life? Brooks shows how this, along with other popular ideas about how to feel more satisfied, can actually produce the opposite effect.

One of the biggest drags on happiness in society is poverty. Having spent years seeking the best way to combat this curse as former president of the American Enterprise Institute, Brooks shares insight on why America's War on Poverty has failed. Could the key to transforming lives lie in shifting our approach from making poverty bearable, to making it truly escapable?

Palmer Luckey is as close as it gets to a real-life Iron Man. As a teenager, he worked on virtual reality headsets until he eventually created the Oculus Rift, the most groundbreaking VR headset ever assembled. After single-handedly shaping the field of virtual reality, and selling Oculus to Facebook, he founded Anduril, one of the fastest-growing defense companies in America today.

While some American tech companies refuse to work with the U.S. military, Anduril is unabashed in its efforts to develop and deploy artificial intelligence, drone technology, and other advanced systems to defend America and its allies. In this conversation, Palmer discusses Anduril’s latest game-changing technologies, innovative ideas that can change the world, his favorite sci-fi novel — and the Fermi paradox! [Joe's venture capital firm is an investor in Anduril.]

This moment in our culture was made for a writer and thinker like Bari Weiss. What can Americans do to beat back the wave of illiberalism currently sweeping through our institutions? Bari Weiss took her stand last summer, resigning from the New York Times to launch her own Substack newsletter. Her courage has since inspired others to defend free speech, diversity of thought, and other core American values.

In this episode, she explains what's at stake today. Left unchecked, "woke" intolerance and groupthink result in real harm to individuals and society—as indicated by many factors, including a recent, worrying rise in anti-Semitic violence. Weiss lays out the case for building new schools, media outlets, and institutions that protect the values that make our republic exceptional.

When Kimbal and Elon Musk immigrated to the U.S. from South Africa to start their first company, they couldn't afford both an apartment and an office—so, unbeknownst to their employees, they slept in the office.

The brothers have come a long way from their humble origins. Today, Kimbal is a highly successful entrepreneur and investor who serves on the boards of Tesla and SpaceX — and in this episode he provides exciting updates for each company. But along the way, the terrorist attacks of September 11, 2001 changed his life forever. Kimbal explains how cooking for firefighters at Ground Zero awakened a passion for creating community through food. He now owns and operates restaurants around the country, while his Million Gardens Movement brings home-grown food to inner-city areas. Joe supports Kimbal's nonprofit and encourages others to do the same (link below).

Million Gardens Movement: https://give.biggreen.org/campaign/fundraiser-million-gardens-movement/c331055 

NOTE: This episode was recorded before many restaurants had fully reopened.

More than 70 percent of child sex trafficking happens online. When Hollywood superstar Ashton Kutcher first heard this statistic, he knew he had to do something to stop it. His efforts took him to Silicon Valley—where, hoping to enlist leading tech entrepreneurs in the fight against online trafficking, he first met Joe. Through their work together, Kutcher's organization, Thorn, has built software and processes that have enabled governments to rescue thousands of children from sexual abuse. [Joe partnered with Ashton in Thorn’s early days to enlist talent, refine strategy, and reach scale, as well as serving on its board.]

Ashton is an innovative technology investor, an extraordinary family man, and a philanthropist. In this episode, he discusses the dangers that face children online, and makes the case for why tech companies should do more to help law enforcement protect the vulnerable. He also weighs in on the future of social media and explains how China could use TikTok to influence the minds of Americans in an anti-U.S. propaganda effort. Finally, he details how his upbringing, with its focus on hard work and perseverance, propelled him from modest origins to his career as a world-famous actor and model. 

Curing cancer, eliminating diseases, reprogramming cells to help 80-year-olds feel like they're 30 -- could it all be possible in our generation?

America is in the midst of a biotech revolution that is transforming modern medicine and will save countless lives. At the forefront is Dr. Rick Klausner, former director of the U.S. National Cancer Institute, co-founder of Juno Therapeutics, GRAIL, and MindStrong Health, renowned scientist, and billionaire innovator.

Dr. Klausner has played a pivotal role in this movement on a number of fronts, not least by discovering how to treat previously incurable end-stage cancers -- and then founding companies that do just that, already saving tens of thousands of lives. And he is just getting started.

In this wide-ranging conversation, Dr. Klausner explains how these remarkable breakthroughs occurred, giving a rundown on the science of cell therapies and their remarkable potential, alongside other new possibilities. As he charts the future of medicine, he also draws upon his wealth of historical knowledge and hints at how modern science could harness recent Nobel-Prize winning breakthroughs to discover the source of youth that eluded sixteenth-century explorer Juan Ponce de León. [Joe briefly confuses Ponce de León with Vasco de Gama.]

NOTE: Joe has invested with Dr. Klausner in multiple companies, most recently in Dr. Klausner's latest venture, Altos Labs.

Check out Season One of American Optimist.