Listener feedback, statin eligibility and Yogi Berra, evidence-based medicine and heterogenous treatment effects, and MRAs in HF are the topics John Mandrola, MD, discusses in this week’s podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I. Listener Feedback

• ASPIRE AF https://classic.clinicaltrials.gov/ct2/show/NCT03968393
• Butala paper: Stroke After TAVR With and Without EPD https://www.ahajournals.org/doi/abs/10.1161/CIRCINTERVENTIONS.123.013697
• PROTECTED TAVR
• Heuts meta-analysis: EPD During TAVR https://heart.bmj.com/content/110/11/757

II. Statin Eligibility

• JAMA-IM: Data Analytic Choices and Predicting Vascular Events https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2819821
• Zeraatker Specification Analysis Paper https://doi.org/10.1016/j.jclinepi.2024.111278
• PCE https://www.mdcalc.com/calc/3398/ascvd-atherosclerotic-cardiovascular-disease-2013-risk-calculator-aha-acc

III. Heterogenous Treatment Effect

• Weisberg and Dailey-Higgs
• DANISH

IV. Heart Failure and MRAs 

• RALES https://www.nejm.org/doi/full/10.1056/NEJM199909023411001
• EMPHASIS https://www.nejm.org/doi/full/10.1056/NEJMoa1009492
• Combined analysis (Matsumoto)

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