Medicine Redefined

Medicine Redefined

By Altamash Raja, DO and Darsh Shah, DOMedicineHealth & Fitness
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Medicine Redefined episodes

  • 182. How The Biggest Loser Revealed the Dark Side of Weight Loss

    Darsh and Altamash dive into Netflix’s Fit for TV and the wild story behind The Biggest Loser. From shocking weight loss tactics to the billion-dollar business of reality TV, tune in as they break down the science of obesity, GLP-1s, and the dark side of weight-loss entertainment.

    Sources: 
    00:01 | Fit for TV (Netflix doc)

    01:30 | The Biggest Loser (NBC show)

    02:50 | Jillian Michaels (trainer)

    03:45 | Bob Harper (trainer)

    04:15 | GLP-1 drugs (Ozempic/Wegovy)

    05:20 | Calories In/Out model

    14:20 | Dr. Robert Huizenga

    15:20 | Motivational interviewing

    15:30 | Metabolic ward studies

    25:20 | NYT: After The Biggest Loser

    25:25 | Kevin Hall (NIH)

    26:00 | Hall et al. 2016 (Obesity)

    27:10 | Yo-yo dieting

    27:30 | Leptin hormone

    30:50 | Alan Aragon (nutritionist)

    32:00 | Set point theory

    32:45 | Stephan Guyenet (author)

    33:20 | Sarcopenia

    35:00 | Temptation challenges

    35:10 | Big Brother (reality show)

    35:15 | Survivor (reality show)

    38:50 | Dr. Mike Varshavski

    39:05 | Dr. Mike Israetel

    39:10 | Aesthetic Revolution (concept/book)

    Thanks for listening!

    52 min
  • 181. The Truth About Menstrual Cycle Training & Hormonal Impacts on Performance | Shawn Arent, PhD, CSCS

    Dr. Darsh Shah and Dr. Altamash Raja continue their conversation with Dr. Shawn Arent on hormone physiology and performance. They dive into female physiology and menstrual cycle myths, the overlooked role of thyroid and reverse T3, catecholamines and autonomic balance, and the future of performance enhancement with GLP-1s and muscle-preserving drugs. A practical, evidence-based look at optimizing health and performance!


    TIMESTAMPS

    00:00 Introduction to Medicine Redefined

    00:37 Deep Dive into Hormone Physiology

    00:54 Female Physiology and Menstrual Cycle

    01:03 Thyroid Hormone Optimization

    01:12 Catecholamines and Autonomic Balance

    01:23 GLP-1 Agonists and Muscle Preservation

    01:58 Guest Introduction: Dr. Shawn Arent

    02:21 Discussion on Female Physiology

    02:29 Menstrual Cycle and Training

    07:28 Hormonal Influence on Injury

    07:50 Autoregulation in Training

    19:03 Thyroid Hormone and Metabolism

    33:55 Catecholamines and Training Response

    40:55 Sympathetic vs. Parasympathetic Dominance

    45:30 Tracking Trends for Better Interventions

    45:53 Wearables and Recovery in Rugby

    46:55 Debunking Post-Workout Downregulation

    50:52 Contextualizing Fitness Advice

    57:06 Balancing Training Methods

    01:04:30 The Role of IGF-1 in Recovery

    01:07:02 GLP-1 Agonists and Muscle Preservation

    01:15:22 Myostatin Inhibitors: The Future of Muscle Growth?

    01:21:25 Final Thoughts on Health and Performance


    The Impact of Menstrual Cycle Phase on Athletes’ Performance: A Narrative Review MDPI

    Current evidence shows no influence of women’s menstrual cycle phase on acute strength performance or adaptations to resistance exercise training Frontiers

    The Effects of Menstrual Cycle Phase on Exercise Performance in Eumenorrheic Women: A Systematic Review and Meta-Analysis Springer

    Influence of Menstrual Cycle Phases on Maximal Strength, Power and High-Intensity Interval Performance – A Systematic Review with Meta-Analysis MDPI

    Evidence-Based Training Guidelines for Elite Women Football and Team Sports Human Kinetics

    Hormones, Hypertrophy, and Hype: An Evidence-Guided Primer on Endogenous Endocrine Influences on Exercise-Induced Muscle Hypertrophy ESSR

    Menstrual Cycle Effects on Sports Performance and Adaptations to Training: A Historical Perspective PubMed

    Effect of Estrogen on Musculoskeletal Performance and Injury Risk Frontiers

    Anterior Cruciate Ligament Injuries in Female Athletes: A Narrative Review of Prevention, Risk Factors, and Management Bone Jt Open

    The Influence of Age on the Effectiveness of Neuromuscular Training to Reduce ACL Injury in Female Athletes: A Meta-Analysis PMC

    Catecholamine and Cardiovascular Responses to Exercise: An Update Springer

    Effects of Different Training Interventions on Heart Rate Variability in People with Overweight and Obesity: A Systematic Review Frontiers

    Blood-Based Biomarkers for Monitoring Workload and Recovery in Athletes Sports Med Open

    Changes in Lean Body Mass with the Use of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss and Strategies to Mitigate LBM Loss Wiley

    ADA Newsroom: GLP-1 Agonists and Lean Body Mass ADA News

    Effects of Subjective and Objective Autoregulation Methods in Resistance Training: A Systematic Review PeerJ

    Biomarkers in Sports and Exercise: Tracking Health, Performance, and Recovery in Athletes Springer

    Exercise, Training, and the HPT/HPA/HPG Axes in Athletes CSMR

    Circulating Testosterone as the Hormonal Basis of Sex Differences in Athletic Performance PMC

    Optimizing Health and Athletic Performance for Women Springer


    Thank you for listening!

    1 hr 27 min
  • 180. The Truth About Cortisol, Insulin & Overtraining | Shawn Arent, PhD, CSCS

    We are back with a powerhouse guest, Dr. Shawn Arent, for part 1 of a series on hormone optimization. From cortisol misconceptions to insulin fearmongering, they cut through the noise with science-backed insight into performance, recovery, and stress physiology. You’ll rethink everything you’ve seen on social media about hormones.


    TIMESTAMPS

    00:00 Introduction to Medicine Redefined

    00:36 Welcoming Dr. Sean Arent

    02:11 The Importance of Cortisol

    02:49 Understanding Cortisol's Role in Performance

    04:59 Chronic Cortisol and Overtraining

    13:51 Monitoring Stress and Performance

    22:30 The Role of Nutrition in Cortisol Management

    33:31 Insulin: The Anabolic Hormone

    39:27 Exercise and Insulin Sensitivity

    40:43 Impact of Stress and Sleep on Glucose Levels

    43:02 Continuous Glucose Monitors: Pros and Cons

    47:42 Athlete Nutrition and Performance

    55:52 Hormonal Responses to Training

    01:07:18 Sex Hormones and Athletic Performance

    01:17:37 Conclusion and Future Topics


    SOURCES

    00:00:22 | Cortisol deficiency (Addison’s disease) is life-threatening

    00:04:42 | Cortisol peaks in early morning (chronobiology) 

    00:05:25 | Acute sleep deprivation significantly increases cortisol 

    00:05:42 | One week of 5h/night sleep restriction lowers testosterone by \~10–15% 

    00:22:11 | Cortisol stimulates gluconeogenesis (maintains blood glucose upon waking) 

    00:27:38 | No single reliable biomarker for overtraining syndrome 

    00:27:38 | Overtrained athletes show blunted HR, blood lactate and cortisol responses 

    00:29:00 | Prolactin rises in response to stress/exercise 

    00:30:00 | Dietary fat guidelines: 20–35% of calories from fat 

    00:33:30 | Insulin is an anabolic hormone promoting nutrient storage 

    00:33:30 | Low-fat (∼20% fat) diets reduce testosterone 10–15% vs high-fat diets 

    00:39:26 | Regular exercise improves insulin sensitivity 

    00:39:26 | ~38% (~98M) of U.S. adults have prediabetes 

    00:40:29 | Shorter sleep duration impairs insulin sensitivity 

    00:01:02:57 | Exercise above the lactate threshold elicits maximal GH release

    01:04:42 | Resting lactate \~1–2 mmol/L; intense exercise >20 mmol/L 

    01:08:53 | Higher testosterone levels correlate with greater lean mass in men 

    01:11:51 | Winners in competition show post-event testosterone spikes 

    01:12:29 | Female athlete amenorrhea leads to low bone density and stress fractures

    01:12:29 | Amenorrheic female athletes have lower IGF-1 (growth factor) 

    01:08:53 | Testosterone even within normal range affects strength/mass

    1 hr 22 min
  • 179. Is Medicine Worth It? Real Talk on Debt, Purpose, and The Future of Doctors

    In this episode of Medicine Redefined, Darsh and Altamash dive deep into the question on every future and current physician’s mind: is medicine still worth it? What starts as a reflection on the financial and emotional toll of the profession quickly evolves into a powerful conversation about agency, reinvention, and longevity in medicine. With honesty and humor, they unpack their own journeys from burnout to building lives and careers on their own terms, sharing hard-earned insights and tactical frameworks for thriving in a changing healthcare landscape.

    If you’ve ever felt disillusioned about your path in medicine or wondered how to break free from the constraints of the job, this episode will challenge and inspire you to rethink what’s possible.


    TIMESTAMPS

    00:00 Introduction to Medicine Redefined

    00:54 Is Medicine Still Worth It?

    02:24 Challenges in Modern Medicine

    05:20 Financial Realities of Medical Education

    10:46 Diversifying Medical Careers

    17:40 The Importance of Diverse Experiences

    22:20 Generational Shifts in Medical Practice

    22:55 The Importance of Professional Diversification

    23:21 Shared Decision Making with Patients

    23:48 Challenging the Culture of Self-Destruction

    24:15 Advice for Aspiring Neurosurgeons

    24:32 Balancing Interests and Professional Growth

    25:54 The Business of Medicine

    27:59 Frameworks for Medical Students

    29:33 Reframing Medical Careers

    33:49 Setting Prices in Direct Pay Practice

    41:18 Final Thoughts and Parting Words


    SOURCES

    | [00:06:45] | One Big Beautiful Bill Act (H.R.1, 119th Congress) – A 2025 budget reconciliation bill passed by the House and signed into law, containing sweeping tax and spending changes (health, taxes, etc.)

     | [00:06:51] | Medicaid coverage cuts – CBO estimated the reconciliation bill would reduce Medicaid enrollment by on the order of 10–12 million people

    | [00:06:53] | Fiscal impact of the bill – Analyses (e.g. by the CRFB) show the bill adds roughly $3.4 trillion to the deficit (≈$4.1 trillion including interest)

    | [00:07:30] | Student loan policy changes – H.R.1 eliminates Grad PLUS loans (effective July 1, 2026) and caps borrowing for medical/law students at $50,000/year ($200,000 total)

    | [00:07:45] | AAMC medical school cost data – The AAMC reports median 4‑year cost of attendance for public med schools ~$286K (2025 cohort, i.e. ~$71–73K/year including living)

    | [00:08:04] | AAMC medical school debt – AAMC data show the median debt at graduation for MD grads is about $205,000

    | [00:09:39] | Primary care physician trend – Reports indicate many U.S. med students are “turning away from primary care in favor of more lucrative specialties”, leading to projected shortages.

     | [00:09:39] | Primary care shortage (projected)

    | [00:09:39] | Overall physician shortage – AAMC projects an all‑specialty physician shortage up to ~86,000 doctors by 2036

     | [00:09:49] | Healthcare spending share (physicians) – U.S. health expenditure data: hospitals ~31% and physicians/clinics ~20% of total spending in 2023 (so physician pay is a fraction of total cost)

     | [00:10:00] | Private equity in healthcare – Deal activity surged in 2024

    | [00:10:05] | PE healthcare deals (2024) – A recent analysis counted ~1,069 private‑equity healthcare deals in the U.S. in 2024.

    | [00:17:15] | Peter Attia – Physician who left surgical residency

    [00:21:09] | Emphasizing diversity of thought and experience in healthcare teams can broaden insight and drive innovation

    [00:21:34] | The notion of a physician “martyr complex”

    [00:32:20] | Nearly 39% of U.S. doctors now have side “gigs”

    [00:33:23] | A 2023 randomized trial (knee bursitis) found local corticosteroid injections relieved pain significantly more than extracorporeal shockwave therapy (ESWT)

    [00:34:16] | Concierge medicine and Direct Primary Care (DPC) are growing trends

    [00:39:58] | Patients paying concierge/DPC fees gain perks (shorter wait times, direct doctor access)


    45 min
  • 178. The Cost of Secrecy in Insurance: Why Transparency Matters | Dr. Vincent Marchese, DO

    In this episode of Medicine Redefined, Dr. Darsh and Dr. Altamash sit down with Dr. Vince Marchese, sports medicine physician and founder of Apex Medicine, to explore how transparency and direct pay models are transforming healthcare.

    We break down why traditional insurance creates confusion and barriers, how clear pricing empowers patients, and what happens when physicians reclaim time to focus on care - not paperwork.


    TIMESTAMPS

    00:00 Introduction to Medicine Redefined00:35 Meet Dr. Vince Marchese01:13 Journey to Sports Medicine01:37 Breaking Away from Insurance02:06 Life as a Direct Pay Practitioner09:33 Understanding Insurance Complexities10:27 The History of Insurance11:56 Navigating the Insurance Maze15:37 The Case for Direct Pay17:31 Empowering Patients with Knowledge41:39 The Insurance Dilemma42:00 State Mandates and Penalties42:58 Self-Insurance and Cost-Saving Strategies44:40 Catastrophic Insurance and HSAs52:04 The Benefits of Direct Pay Models55:02 Building a Patient-Centric Practice01:04:31 Scaling and Future of Direct Pay Medicine01:11:44 Support Systems and Taking the Leap01:16:03 Closing Thoughts and Resources


    SOURCES

    Healthcare Spending & Insurance Costs

    [00:16:01] “51 cents of every healthcare dollar goes to insurance” – In fact, CMS and KFF data show [1, 2] private insurers cover ~30% of U.S. health spending, and federal/state programs ~51%. Administrative overhead is only about 7.4% of spending [1]. 

    [00:10:00] Average premium costs – Kaiser Family Foundation reports that in 2024 the average annual employer health insurance premium is ~$8,951 for single coverage and ~$25,572 for family coverage [4], illustrating why monthly premiums can seem “crazy high.”

    Policy & Regulations

    [00:31:54] Balance billing protections (No Surprises Act) – Effective Jan 1, 2022, federal law bans surprise/“balance” bills for most emergency and certain other out-of-network services [5, 6]. For example, CFPB explains that patients generally will no longer face balance bills for emergency care [5, 6] under the No Surprises Act.

    Health Savings Accounts (HSAs)

    [00:43:30] Triple tax advantage of HSAs – HSAs are truly tax-advantaged. According to IRS rules and financial guides, HSA contributions are tax-deductible, earnings grow tax-free, and qualified withdrawals are tax-free [7, 8]. Bank of America and IRS publications both highlight this “triple-tax” benefit.

    [00:44:17] HSA contribution limits – For 2024, IRS rules allow $4,150 annual HSA contributions for self-only HDHP coverage and $8,300 for family coverage [7] (The podcast guest’s “~$4,000” estimate for solo coverage aligns with the $4,150 limit for 2024 [7]).

    Price Transparency & Cash Payments

    [00:21:30] MRI cash prices – Pricing guides show that uninsured (cash) MRI costs vary widely. For example, a 2025 SingleCare review finds a national average MRI cost of ~$1,325 (range ~$400–$12,000) without insurance [9]. A cash-pay platform (MDsave) reports a $1,335 average for an MRI, with their cash price as low as ~$805 [10]. These sources confirm that self-pay MRI prices can be far below billed/insurance prices.

    [00:21:30] Cash vs. negotiated prices – Studies show many hospitals set their cash (self-pay) rates lower than insurer-negotiated rates. For example, one analysis found 60% of insurer-negotiated hospital rates exceed the hospital’s cash price for the same service [11], and a JAMA-published study reports that cash prices are often below the commercial prices insurers pay [12]. In short, paying cash (or high-deductible plans) can sometimes cost less than the “discounted” insurance rate.


    Referenced Book
    [00:21:24] The Price We Pay – Dr. Marty Makary

    1 hr 18 min
  • 177. Ketamine, Trauma, and the Future of Psychiatry | Rocky Sullivan, DO

    In this episode of Medicine Redefined, Darsh and Altamash sit down with Dr. Patrick “Rocky” Sullivan, an emergency physician turned ketamine therapy pioneer, to explore how this powerful molecule is quietly transforming mental health care. Drawing from years of ER experience and clinical innovation, Dr. Sullivan breaks down the science, stigma, and promise behind ketamine treatment for depression, PTSD, addiction, and chronic pain.

    We unpack the nuances of off-label prescribing, why most depression treatments miss the mark, and how ketamine-assisted psychotherapy (KAP) is helping patients rewire trauma in real time.

    If you’ve ever wondered how ketamine really works, who it's for (and who it’s not), or what a responsible treatment plan should look like, this conversation will change your perspective. It's an eye-opening look into the future of mental health care.

    TIMESTAMPS

    00:00 Introduction to Medicine Redefined

    00:36 Meet Dr. Patrick Sullivan

    01:46 The Evolution of Ketamine Therapy

    03:18 Rocky's Journey into Psychiatry

    07:57 Understanding Ketamine's Mechanism

    08:49 Off-Label Uses and Research

    11:12 Ketamine in Emergency and Pain Management

    14:14 The Importance of Set and Setting

    15:29 From Anesthetic to Antidepressant

    17:15 Mainstream Depression Treatments

    23:02 Navigating Treatment Options

    26:45 Screening and Safety Protocols

    37:29 Ketamine Assisted Psychotherapy

    41:42 Telehealth and Ketamine Delivery

    42:16 The Importance of Provider Interaction

    43:11 Case Studies: Depression and OCD

    43:55 Case Studies: Pain and Trauma

    44:24 Case Studies: Alcohol Use Disorder

    46:12 The Role of Therapy in Ketamine Treatment

    47:54 Ketamine's Mechanism and Benefits

    52:09 Maintenance and Dosage Variability

    01:05:13 Challenges in Ketamine Research and Regulation

    01:16:14 Conclusion and Contact Information

    SOURCES

    04:13: Ketamine suicidal ideation meta-analysis; Ketamine depression meta-analysis

    05:09: What is ketamine?

    06:01: History of ketamine

    07:36: Off-label prescriptions

    07:44: Research referenced on alcoholism and ketamine:

    • 1997 study

    • 1998 study

    • 2001 study

    • 2018 study

    07:44: 2000 study done on depression and ketamine

    07:44: 2006 study repeated

    09:30: Ketamine dose-dependent responses

    10:13: Ketamine on respiratory drive

    10:58: Ketamine for asthma

    13:47: Psychedelic therapy

    15:21: Treatment-resistant depression

    16:18: SSRIs and other antidepressant drugs

    17:36: ECT and Ketamine therapy studies:

    • Study 1

    • Study 2

    • Study 3 (70% statistic)

    18:48: TMS

    18:48: Spravato study

    18:48: IV Infusion ketamine study

    22:19: Treatment resistance depression prevalance

    25:20: Mathew Perry story

    28:05: Studies on how Ketamine works in the brain:

    • Study 1

    • Study 2

    29:30: Adjustment disorders

    32:21: Studies on BDNF and ketamine:

    • Study 1

    • Study 2

    • Study 3

    • Study 4

    32:37: Exercise and BDNF 

    32:39: HIIT and BDNF

    35:08: Ketamine assisted psychotherapy research

    38:08: Ketamine for PTSD

    44:27: EMDR

    44:46: How to change your mind:

    • Documentary

    • Book

    01:04:25: Ketamine is top-studied drug in depression

    01:05:40: Low-dose naltrexone

    01:06:00: FDA approval for naltrexone

    01:07:23: American Society of Ketamine Physicians, Psychotherapists & Practitioners

    01:14:02: Rocky’s website!

    1 hr 19 min
  • 176. Pills, Profits, and Power: The Fight to Reform Big Pharma | Vinay Patel, PharmD

    In this episode of Medicine Redefined, Darsh and Altamash take a deep dive into the complex world of medications with Dr. Vinay Patel, pharmacist and founder of MakoRx. Dr. Patel exposes the hidden realities behind Big Pharma, explaining why generic drugs can be so confusing and revealing the true factors driving skyrocketing pharmacy prices. We also explore how cutting-edge AI technology is revolutionizing drug discovery and development.

    This conversation will fundamentally change how you understand the medications you rely on every day. Whether you’re a healthcare professional or simply curious, this episode delivers powerful knowledge and a fresh perspective. Tune in!


    TIMESTAMPS

    00:00 Introduction to Medicine Redefined00:36 Meet Vinay Patel: Healthcare Innovator01:04 Understanding PBMs: The Hidden Middlemen02:47 The Evolution of PBMs05:29 Vertical Integration and Its Impact15:52 The Complexities of Drug Pricing26:30 Compounding Pharmacies and GLP-1 Medications34:15 Mark Cuban's Cost Plus Solution37:39 The Dominance of Employer-Based Health Insurance39:46 The Generic vs. Brand Medication Debate40:52 Challenges in Generic Drug Manufacturing45:05 The Role of Pharmacists in Medication Management50:50 Solutions for a Broken Healthcare System53:54 Introduction to Make O Rx58:29 Overcoming Barriers in the Healthcare Market01:01:31 The Future of Pharmaceuticals and AI01:05:54 Key Takeaways for Healthcare Providers01:08:04 Final Thoughts and Contact Information

    SOURCES

    • 00:19: Price We Pay Book

    • 01:35: Pharmacy Benefit Management History

    • 03:24: Medical Modernization Act

    • 03:53: Affordable Care Act

    • 04:13: Vertical Integration

    • 04:33: Big Three Control 80% of Prescriptions

    • 04:56: 20% of Smaller Companies

    • 05:40: Tyson Foods RightWay

    • 06:01: Smaller PBMs Gaining Traction

    • 07:42: Antitrust enforcement in healthcare

    • 08:22: Affordable Care Act and High Deductible Plans

    • 09:24: Gag clauses

    • 09:58: Trump’s Law to Eliminate Gag Clauses

    • 10:39: Elizabeth Warren and Josh Hawley's Bill on PBMs

    • 13:25: Clawbacks

    • 14:32: Clawback disclosure law

    • 14:52: Losing money on drugs

    • 15:00: GLP-1 drugs

    • 16:27: Info on drug pricing

    • 17:05: Insurance companies set drug prices

    • 22:01: Article on rebates

    • 22:30: Net prices have gone down

    • 22:39: List prices have gone up

    • 24:21: Deep dive into drug prices in US

    • 24:45: US VS Europe drug pricing

    • 26:49: US subsidizes the world’s drug prices

    • 27:32: History of Ozempic

    • 28:31: Current status of Ozempic shortage

    • 29:11: Compounding drugs law

    • 32:21: Compounding pharmacy creditation

    • 34:42: Alliance for pharmacy compounding

    • 35:35: Cost plus

    • 36:16: NADAC

    • 39:27: Number of people on employer health insurance

    • 41:35: Bottle of lies

    • 56:55: Mako RX


    Dr. Vinay Patel’s contacts:


    1 hr 12 min
  • 175. Cynicism in Healthcare: New Surgeon General, Critiquing Viral Health Experts & Getting on Board with AI

    In this episode, Darsh and Altamash talk about why so many people feel let down by the healthcare system. They break down where trust has gone wrong, how rising costs and confusing policies leave both patients and doctors frustrated, and why it feels like "no one is coming to save you". They also get into AI’s growing role in medicine, the recent Surgeon General pick, and what it means to get on board with AI.


    00:00 Introduction (Dr. Darsh hates on LeBron)

    00:49 Setting the Stage: Healthcare System Frustrations

    01:58 Theme 1: Erosion of Trust in Healthcare

    15:12 Theme 2: Financial Burden and Affordability Crisis

    23:32 Theme 3: Systemic Pressures and Burnout

    31:28 The Future of Medical Education

    31:48 AI in Medical Decision Making

    33:15 The Rapid Advancement of AI

    33:46 AI's Impact on Jobs and Society

    37:24 Healthcare System Challenges and Layoffs

    39:43 Controversial Surgeon General Nomination

    47:22 Functional Health and Longevity Market

    55:49 Accountability in Health and Society


    Resources mentioned in the show:

    • 03:30 Public Trust fell after COVID

    • 04:09 UHC Medicare Fraud case

    • 04:38 21st Century Cures Act

    • 14:24 The Price We Pay book

    • 29:30 Simon Sinek ranting about soft skills

    • 30:14 People referenced:

      • Vanessa Van Edwards

      • Vin Giang

      • Jefferson Fisher

    • 33:03 Chat GPT study

    • 34:41 Sergey Brin interview

    • 35:02 AI Singularity

    • 36:16 Morgan Housel podcast

    • 39:30 Nobel Prize study

    • 47:32 Healthcare huddle

    • 47:41 Function health acquiring Ezra

    • 47: 57 Function health

    • 50:53 Dr. Mike Episode with Prenuvo

    • 50:50 Dr. Mike Episode with Eric Topol

    • 56:28 David Wiss Episode

    • 57:27: Young people can’t pass military test

    • 57:47: I, Robot movie

    • 59:38: Indistractable book


    DEEP DIVE:

    • 04:17 Distrust in pharmaceutical companies

    • 15:45 Medical debt bankruptcies

    • 15:57 Exponential growth of healthcare costs

    • 16:12 35% of Americans cannot afford quality healthcare

    • 17:10 Law that stops emergency rooms from refusing care:

    • 18:04: Healthcare premiums have been increasing over time

    • 18:27 Laws and regulations for price transparency: 

      • Link 1

      • Link 2

      • Link 3

      • Issues with compliance

    • 18:49 Drug pricing transparency

    • 23:46 Healthcare burnout at all time high 

      • COVID and the impact on burnout

    • 24:12 Average medical school debt accrued

    • 24: 17 Average doctor salary

    • 26:10 Generational divide between new and old doctors

    • 37:23 Tech Layoffs

    • 37: 43 Stand up for science

    • 37:52 Schools losing funding

    • 41:49 Red 3 ban

    • 42:21 Surgeon general completed med school but not residency
    • 46:47 RFK don’t listen to me on vaccines

  • Thank you for listening, let us know your thoughts!

    1 hr 4 min
  • 174. The Torn ACL Dilemma: Should Every Athlete Get Surgery? | Jeremy Boyd, PT, DPT

    We welcome back Dr. Jeremy Boyd for a deep dive into one of the most debated injuries in sports medicine: the ACL tear. Building on our previous conversation around philosophy and mindset in rehab, this one gets tactical—real tactics, real strategies, and real challenges.


    Topics Covered in the Episode:

    • The 4 main pathways for ACL injury management: reconstruction, repair, non-operative rehab, and cross-bracing for regeneration/recovery

    • What makes someone a coper—and how to identify them safely

    • ACL rehab with a unique blend of manual therapy, neurocognitive testing, and performance training

    • Why rehab isn’t just physical—it’s psychological and personal

    • Risks and benefits of surgery vs. non-op management (and shared decision-making)

    • ACL self-healing and of course, the use of orthobiologics in ACL healing

    • What every patient recovering from an ACL tear should know.

    Resources Mentioned in the show:

    ⁠Cross Bracing Protocol⁠

    ⁠ACL Self-healing study⁠

    ⁠KANON trial for non-op ACL healing⁠

    ⁠PRP for ACL injuries

    1 hr 32 min
  • 173. Why Rehab Fails—And What Truly Heals | Jeremy Boyd, PT, DPT

    Dr. Jeremy Boyd, founder of Trifecta Therapeutics, a sports rehabilitation and performance practice with three locations in Southern NJ/Greater Philadelphia, is residency and fellowship trained and board-certified in Orthopaedic and Sports Physical Therapy. As a Fellow of the American Academy of Orthopaedic Manual Physical Therapists (FAAOMPT), he demonstrates advanced skills in diagnosing and treating complex neuromusculoskeletal conditions, utilizing a comprehensive approach that integrates advanced manual therapy and psychological considerations. Dr. Boyd's expertise is trusted by elite athletes from the NFL, NBA, MLB, and the Olympics, and he has a particular interest and focus on ACL injuries and rehabilitation within his practice.


    Topics covered in this episode:

    • Why manual therapy remains so polarizing — and what the research actually says
    • How to tease out whether patient “failed” rehab or the rehab actually failed the patient
    • The critical role of therapeutic alliance in patient outcomes
    • The downsides of social media misinformation in rehab and healthcare
    • How to properly dose both exercise and rest for high performers
    • Practical advice for physicians and clinicians to evaluate the quality of a rehab program


    Resources mentioned in the show:

    • Adam Meakins — The Sports Physio

    • Adriaan Louw — Pain Neuroscience Education

    • Change Maker by John Berardi

    • Range by David Epstein

    • Mastery by Robert Greene


    Connect with Jeremy Boyd

    • Trifecta Therapeutics

    • Jeremy Boyd — @thedecentdoctor


    1 hr 14 min

About Medicine Redefined

From the publisher's feed

Medicine Redefined challenges outdated conventions by elevating conversations around what health truly means. Hosts Dr. Darsh Shah and Dr. Altamash Raja spotlight clinicians, scientists, thought…

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