11.30.2023 - By Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist
On this podcast episode, I discuss meperidine pharmacology, adverse effects, pharmacokinetics, drug interactions, and much more!
Meperidine is an opioid that is seldom used due to neurotoxicity. I describe how this can happen in this podcast episode.
Meperidine has numerous drug interactions and using a CYP3A4 inhibitor may increase the risk for toxicity.
Seizures are a risk with meperidine due to its neurotoxic metabolite normeperidine. I discuss this further in this podcast episode.