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In this episode, Mikki speaks with Hannah Cabre from Pennington Biomedical Research Center about energy expenditure, body composition, ageing, and what really happens to metabolism through midlife and beyond with a focus on sex differences. 

Hannah’s work uses doubly labelled water data, considered the gold standard for measuring total daily energy expenditure in real-world conditions. This allows researchers to understand what people actually burn across the day, beyond estimates from fitness trackers, calorie equations, or short-term lab measures.

Mikki and Hannah discuss the idea that metabolism is “stable” from 20 to 60, whether menopause uniquely affects energy expenditure, why body fat can increase even when scale weight stays the same, and why preserving fat-free mass becomes increasingly important with age.

This is a nuanced, evidence-based conversation for anyone interested in metabolism, midlife body composition changes, and what ageing really means for energy needs.

https://www.pbrc.edu/research-and-faculty/faculty/cabre-hannah.aspx

Hannah E. Cabré, PhD, RD, is an Assistant Professor at Pennington Biomedical Research Center and Director of the Aging, Gynecology, and Endocrinology Laboratory. Her research focuses on how female sex hormones influence nutrition, health, performance, and body composition across the lifespan, with a particular interest in sex differences during ageing.

Hannah’s work explores the importance of skeletal muscle maintenance for long-term health, especially during the menopause transition, and how lifestyle interventions may help mitigate age-related changes in body composition and healthspan. 

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