Mikkipedia

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This week on the podcast, Mikki speaks to Dr. Eric Ravussin, one of the world’s leading researchers in human metabolism, obesity, and energy balance. Over several decades, Dr. Ravussin’s work has helped reshape how scientists think about body weight regulation, moving the conversation beyond the simplistic idea of “calories in versus calories out” to a deeper understanding of the biology that governs appetite, energy expenditure, and fat storage.

In this conversation, Mikki and Eric explore the brain’s role in regulating body weight, the influence of genetics and environment, and what his landmark research — including work with the Pima population and the CALERIE trial — has revealed about metabolic adaptation, calorie restriction, and longevity. They also discuss spontaneous physical activity, the concept of a body-weight “settling point,” and the emerging role of GLP-1 medications in obesity treatment. It’s a fascinating look at the physiology of weight regulation and why maintaining weight loss is often far more complex than most people realise.

About Dr. Eric Ravussin

Dr. Eric Ravussin is an internationally recognised researcher in metabolism, obesity, and energy balance. He is Associate Executive Director for Clinical Science at the Pennington Biomedical Research Center at Louisiana State University, one of the world’s leading institutions for metabolic research.

For more than three decades, Dr. Ravussin’s work has focused on understanding the biological drivers of obesity and weight regulation, including energy expenditure, metabolic adaptation, appetite regulation, and the role of genetics in body weight. His research with the Pima population helped illuminate the powerful interaction between genetics and environment in the development of obesity.

Dr. Ravussin has also been a principal investigator in the landmark CALERIE (Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy) trial, the first long-term randomised controlled trial examining the physiological effects of sustained calorie restriction in humans, including its potential implications for metabolic health and longevity.

He has authored hundreds of scientific publications and remains a leading voice in research exploring how biology, behaviour, and environment interact to shape body weight and metabolic health.

Prof Ravussin’s faculty profile:

https://www.pbrc.edu/research-and-faculty/faculty/Ravussin-Eric-PhD.aspx 

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This week on the podcast, Mikki speaks to Dr Libby Weaver about one of the most overlooked — and underestimated — drivers of women’s health challenges: iron. 

Dr Libby is a nutritional biochemist, bestselling author and internationally recognised speaker who has spent decades educating both practitioners and the public on the biochemical underpinnings of fatigue, anxiety, hormonal disruption and low resilience. In this conversation, she brings her trademark ability to connect physiology with lived experience, unpacking why she so often says, “fix iron first.”

Together, they explore iron beyond the anaemia narrative — diving into its role in neurotransmitter production, thyroid function, metabolism, perimenopause, and even ADHD. They discuss why iron deficiency remains under-recognised in teenage girls and health-conscious women alike, how inflammation and gut health can silently impair absorption, and why wide reference ranges don’t always reflect optimal wellbeing.

Dr Libby also shares practical insights on testing, common absorption mistakes, and the health stories women need to stop accepting as “normal.” 

This is a grounded, physiology-first discussion that reframes fatigue, anxiety and “just hormones” through a biochemical lens — and offers clear, practical takeaways for women who want to feel genuinely well, not just told they’re normal.

Libby https://drlibby.com/pages/about-dr-libby

Bioblends (incl iron) https://www.bioblends.com/ 

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Is breakfast really the key to weight loss—or is that just a decades-old narrative we’ve never properly questioned?

In this Mini Mikkipedia episode, Mikki unpacks what the highest-quality research actually says about breakfast and fat loss. While observational data suggests breakfast eaters tend to be leaner, randomized controlled trials tell a different story: simply adding breakfast doesn’t cause weight loss—and may even increase daily calorie intake.

But that’s not the end of it. When we zoom in on meal timing and breakfast composition, a more useful pattern emerges. A protein-rich, substantial breakfast eaten earlier in the day may improve appetite regulation, reduce evening overeating, and support long-term adherence to a calorie deficit.

If you’ve ever wondered whether you “should” be eating breakfast for fat loss, this episode delivers the nuance you actually need.

What You’ll Learn

• Why RCTs show breakfast alone doesn’t drive weight loss
• How front-loading calories can improve hunger regulation
• The 30g protein + 350 calorie breakfast threshold
• Why meal timing affects appetite more than metabolism
• When skipping breakfast might still work

Contact Mikki:
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This week on the podcast Mikki chats to Dr Cliff Harvey about what’s trending in 2026 in the nutrition and health space amongst a host of other topics!

Cliff Harvey, PhD, is New Zealand’s expert on the effects of a ketogenic diet in a healthy population, but so much more than that. He has been  helping people to live healthier, happier lives, and to perform better since starting in clinical practice (way back...) in the late 1990s. Over this time he has been privileged to work with many Olympic, professional, Commonwealth and other high performing athletes. He has also worked with many people to overcome the effects of chronic and debilitating health conditions. Along the way he has founded or co-founded many successful businesses in the health, fitness and wellness space, including  Holistic Performance Institute, NZ’s leading certification and diploma for health, nutrition, health coaching and performance that has many of the world experts teaching on the course, so students are learning from the best.

Cliff has  over 20 years experience as a strength and nutrition coach and, in addition to his PhD research, he is a Registered Clinical Nutritionist, qualified Naturopath (Dip.Nat – NCNZ) and holds a diploma in Fitness Training (AUT) and Health Coaching in Patient Care.

You can find Cliff over at https://cliffharvey.com/

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Artificial sweeteners—especially aspartame—have become one of the most controversial topics in nutrition. Does aspartame spike insulin? Trigger hunger? Disrupt metabolism? Increase diabetes risk?

In this Mini Mikkipedia episode, Mikki breaks down a comprehensive meta-analysis published in Advances in Nutrition reviewing over 100 human randomized controlled trials on aspartame. The findings challenge many of the common narratives circulating online.

You’ll learn what actually happens to blood glucose, insulin, appetite hormones, and calorie intake when people consume aspartame—and why the feared “insulin spike without glucose” mechanism doesn’t hold up physiologically. Mikki also unpacks concerns around methanol and amino acid breakdown products, and explains why observational studies often drive misleading headlines.

If you enjoy a diet drink and worry it’s sabotaging your fat loss or metabolic health, this episode offers clarity grounded in human clinical data—not fear-based speculation.

Highlights

• Why aspartame does not trigger insulin spikes in human trials
• What the research shows about hunger, appetite hormones, and calorie intake
• The difference between observational studies and randomized controlled trials
• Methanol, phenylalanine, and aspartic acid: dose, context, and perspective
• Whether diet drinks interfere with weight loss or metabolic flexibility

Contact Mikki:
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NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz
Save 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.com
Curranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.com
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NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz

This week on the podcast Mikki speaks to Sarah Kennedy, cofounder of Calocurb. They discuss the origins of the product and how Amarasate was discovered, how it works, why it’s potentially better than taking a synthetic version of GLP-1 agonist, how it works with your body, and why it’s the only product on the market that has clinical evidence behind its use in this space. They also discuss the efficacy of it, how to use it and what users should expect. This was a great conversation for anyone considering a GLP-1 or coming off a GLP-1, pros and cons all covered.

Listeners of the show can get 10% off their purchase by using the code Mikkipedia10 at www.calocurb.co.nz

Sarah Kennedy is the Chief Executive Officer of Calocurb and a commercial leader in New Zealand’s biotechnology sector. With a background in health innovation, strategy, and global commercialisation, Sarah has played a central role in bringing Calocurb’s proprietary bitter hops extract, Amarasate®, to international markets as a natural appetite-support supplement grounded in gut–brain axis research.

Prior to leading Calocurb, Sarah built extensive experience across life sciences, nutraceuticals, and technology-driven ventures, working at the intersection of science translation and consumer health. She is known for her ability to bridge rigorous research with practical application, guiding multidisciplinary teams through product development, regulatory pathways, and global distribution.

Under her leadership, Calocurb has expanded internationally, positioning New Zealand-derived functional ingredients at the forefront of evidence-informed metabolic health solutions.

Sarah Kennedy : https://www.linkedin.com/in/sarah-kennedy-0a840b13/ 

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On this episode of Mikkipedia, Mikki tackles binge eating behaviours and why the traditional “just eat less” approach often fails. She clarifies the difference between occasional overeating and true binge episodes, including the defining feature of loss of control, and outlines the DSM-5 criteria for binge eating disorder (for education, not self-diagnosis). Mikki then unpacks the physiology and psychology driving the restriction–binge cycle: dopamine and reward circuitry, cortisol and stress, shifts in ghrelin and leptin during calorie deficits, and the classic “what-the-hell effect” described in restraint theory. Most importantly, she offers practical strategies — predictable meals, adequate protein and energy, flexibility over rigidity, understanding whether you’re a moderator or abstainer, and building alternative coping tools — so you can decide whether fat loss is appropriate now or if foundational work comes first.

Highlights

• Binge eating vs overeating: the critical difference
• DSM-5 criteria explained clearly and practically
• Why calorie restriction increases biological pressure to overeat
• Restraint theory and the “what-the-hell” effect
• Practical steps to break the restriction–binge cycle

Contact Mikki:
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NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz
Save 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.com
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Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.com

This week on the podcast, Mikki speaks with Ashley Borden, an award-winning personal trainer and long-time fitness industry leader with decades of experience. This is a wide-ranging conversation about fitness and health, but also about standards, expectations, and what it really means to work in the fitness industry over the long haul. Ashley draws on her years of hands-on coaching and industry experience to reflect on how the space has evolved, what’s improved, and where things have arguably drifted off course. It’s a grounded, thoughtful discussion about doing the fundamentals well, maintaining professional standards, and building a sustainable career in an industry that’s always chasing the next trend.

Ashley Borden is a globally recognized, award-winning certified master personal trainer, fitness and lifestyle expert, and published author with over 55,000 hours of hands-on experience transforming bodies and lives. She’s built a multiple seven-figure career working with a wide range of clients—from everyday individuals to CEO’s, first responders, professional athletes, entertainers, and high-profile celebrities. Her expertise has been showcased on major television platforms including The Kelly Clarkson Show, The Today Show, The Doctors, Discovery Health, Rachael Ray, and as a head coach on multiple seasons of E!’s Revenge Body with Khloé Kardashian. 

Ashley’s training philosophy blends science-based strength work, practical movement mastery, and mindset transformation. Her insights have appeared in InStyle, Vogue, Elle, Shape, Women’s Health, Self, and internationally in Vogue Arabia and Harper’s Bazaar Russia. She is co-author of Your Perfect Fit (McGraw-Hill) and an ambassador for Best Friends Animal Society. Outside fitness, she holds a blue belt in Brazilian Jiu-Jitsu and teaches self-defense with her partner, 2nd degree black belt Duda Guerra.

Ashley ashleyborden.com

IG https://www.instagram.com/ashleybordenfitness/ 

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Contact Mikki:
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Most people don’t quit fat loss at the start, when motivation is high, or at the end, when results are obvious. They quit in the middle. In this Mini Micropedia episode, Mikki unpacks why the middle phase of fat loss feels so uncomfortable, confusing, and tempting to abandon—and why it’s actually where success is decided. Drawing on Seth Godin’s concept of The Dip, Mikki explains how slowing scale changes, rising hunger, reduced novelty, and fuzzy feedback loops can make perfectly normal progress feel like failure. She breaks down the physiological and psychological shifts that happen during sustained fat loss, the three common lies people tell themselves in the middle, and why chasing a “new plan” is usually the worst move. This episode reframes the middle not as a problem to fix, but as the work itself—and shows how staying the course builds habits, self-trust, and sustainable results.

Highlights / Topics Covered

• What “The Dip” is and why it shows up in fat loss
• Why slow progress doesn’t mean stalled progress
• The three lies that derail people mid-journey
• Reframing success as adherence, not scale movement

Contact Mikki:
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NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nz
Save 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.com
Curranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order