Amb l'ajuda del periodista Miquel Jurado farem un recorregut per les ribes musicals del Mississippí, una artèria fluvial que travessa milers de quilòmetres i que ens servirà per fer "collage" de músics, cançons, estils i escenes lligades al seu voltant.

01 Louis Armstrong - "St. Louis blues"

02 Jimmy Lunceford - "Cement mixer"

03 Arthur "Big Boy" Crudup - "That's all right"

04 Jackie Brenston - "Rocket 88"

05 Sonny Criss - "Wailin' with Joe"

06 The Mar-Keys - "Last night"

07 Dirty Dozen Brass Band - "John the revelator"

08 Robert Johnson - "Cross road blues"

09 John Lee Hooker - "Boogie chilun"

10 B.B. King - "Sweet little angel"

11 Teddy Edwards - "Good gravy"

12 Billie Holiday - "Strange fruit"

13 Huey "Piano" Smith - "Rockin' pneumonia & the boogie woogie flu"

14 Dirty Dozen Brass Band - "My feet can't fail me now"

15 Louis Prima - "St. Louis blues"