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In recent weeks, there has been an outbreak of severe Kawasaki-like disease at the Italian epicenter of the SARS-CoV2 epidemic and as of May 12, the state of New York Health Department had identified 102 kids with potential infection. Up to this point, our pediatric population had seen a relatively mild disease course during this pandemic, but these recent developments have captured the attention of pediatricians, parents and the global news media. Yesterday the CDC officially named this the Multisystem Inflammatory Syndrome in Children, Associated with COVID-19. In this, our 13th COVID-19 podcast we will cover the clinical presentation of MIS-C, how it differs from Kawasaki's and what the early literature is saying.

Sam Dominguez, MD, PhD, is an Infectious Disease physician at Children's Colorado and Associate Professor of Pediatrics at the University of Colorado School of Medicine.

Todd Carpenter, MD, is Director of the Pediatric Intensive Care Unity at Children's Colorado and Professor of Pediatrics at the University of Colorado School of Medicine.