Recent FDA actions have brought renewed attention to leucovorin as a potential treatment for managing symptoms associated with autism spectrum disorder. This course explores the clinical distinctions between autism and cerebral folate deficiency, reviews key evidence behind leucovorin use, and outlines counseling considerations relevant to pharmacy practice. You will gain clarity on this complex and evolving topic to better support informed, evidence-based care.

HOST
Rachel Maynard, PharmD
GameChangers Podcast Host and Clinical Editor, CEimpact
Lead Editor, Pyrls

GUEST
Geoff Wall, PharmD, FCCP, BCPS
Professor of Pharmacy Practice
Iowa Methodist Medical Center

Rachel Maynard and Geoff Wall have no relevant financial relationships to disclose.
 
 
CPE REDEMPTION
This course is accredited for continuing pharmacy education! Click the link below that applies to you to take the exam and evaluation:

• If you are already enrolled in this course, click here to redeem your credit. 
• To purchase this episode and claim your CPE credit, click here. 

CPE INFORMATION
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Describe current clinical evidence related to the use of leucovorin in autism and cerebral folate deficiency.
2. Identify key counseling considerations for pharmacists discussing leucovorin therapy with patients and caregivers.

0.05 CEU/0.5 Hr
UAN: 0107-0000-25-363-H01-P
Initial release date: 12/1/2025
Expiration date: 12/1/2026
Additional CPE details can be found here.

Follow CEimpact on Social Media:
LinkedIn
Instagram