Neurology® Podcast

1) Transient RLS and 2) Topic of the month: Treatment of tremor in PD. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alberto Espay interviews Dr. Mauro Manconi and Prof. Luigi Ferin-Strambi about their paper on transient RLS. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about medullary signs in neuromyelitis optica. In the next part of the podcast Dr. Shanna Patterson interviews Dr. Blair Ford about medical treatment of tremor in PD for our Lesson of the Week. Next week, we will highlight the second part of this interview which will discuss surgical treatment of tremor. The participants had nothing to disclose except Drs. Espay, Overman, Ford and Prof. Luigi Ferin-Strambi. Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.Prof. Ferini-Strambi serves as Field Editor for Sleep Medicine. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Ford serves on the scientific advisory board for Medtronic, Inc., and receives in his clinical practice as Medical Director for Movement Disorder Surgery at Columbia University (25% effort).

1) AAN quality measures on Parkinson disease and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Eric Cheng about the AAN quality measures on Parkinson disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Guillain-Barre mimics: Amiodarone neurotoxicity. In the next part of the podcast Dr. Beau Bruce interviews Dr. James Howard for the last part of our discussion on neuro-muscular disease with this week being about acetylcholine esterase inhibitors for our Lesson of the Week. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Burns, Cheng and, Overman. Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Cheng serves as a consultant for the National Parkinson Foundation; and receives research support from the NIH/NINDS (K23NS058571 [PI]), the VA Parkinson's Disease Research, Education, and Clinical Center, the Department of Veterans Affairs, the California Office of Statewide Planning and Development, the National Multiple Sclerosis Society, and the American Heart Association. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.

1) Corticobasal syndrome and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alberto Espay interviews Drs. Jennifer Whitwell and Keith Josephs about their paper on corticobasal syndrome. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Guillain-Barre mimics: Buckthorn neurotoxicity. In the next part of the podcast Dr. Beau Bruce interviews Dr. Rahman Pourmand for the next part of our discussion on Lambert-Eaton myasthenic syndrome for our Lesson of the Week. The participants had nothing to disclose except Drs. Espay, Whitwell, Josephs, and Overman. Dr. Espay received has personal compensation as a consultant for Boehringer Ingelheim; grant support from Codman; Medtronic, Inc; Allergan, Inc.; and CleveMed, and honoraria from UCB-SCHWARZ PHARMA AG; Medtronic, Inc. and Novartis.Dr. Whitwell receives research support from the Dana Foundation and the NIH (R01- DC010367 [coinvestigator] and R01-AG037491 [coinvestigator]).Dr. Josephs receives research support from the NIH (NIDCD R01- DC010367 [PI], NIA R01-AG037491 [PI], and NINDS 2P50 NS040256-10 [coinvestigator]) and the Dana Foundation.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.

Hallucinations and sleep disorders and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Scott Kohler interviews Drs. Christopher Goetz and Glenn Stebbins about their paper on hallucinations and sleep disorders in PD. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about mimics of Guillain-Barre syndrome. In the next part of the podcast Dr. Beau Bruce interviews Dr. Gil Wolfe for the next part of our discussion on treatments for myasthenia gravis for our Lesson of the Week. The participants had nothing to disclose except Drs. Goetz, Stebbins, and Overman. Dr. Goetz serves on a scientific advisory board for the Parkinson's Disease Foundation; served as Editor-in-Chief of Movement Disorders; receives royalties from the publication of Textbook of Clinical Neurology, 3rd edition (Saunders, 2007) and Jean-Martin Charcot: Constructing Neurology (Oxford University Press, 1995); has served as a consultant for Asubio Pharmaceuticals, Inc., Boehringer Ingelheim, IMPAX Laboratories, Inc., i3 Research, Ingenix, Neurim Pharmaceuticals, Novartis, Osmotica Pharmaceutical Corp., Oxford BioMedica Plc, Solvay Pharmaceuticals, Inc., Solvay Pharmaceuticals, Inc., Teva Pharmaceutical Industries Ltd., United Biosource Corporation and UCB; receives research support from Boehringer Ingelheim, Ceregene, Merck Serono, Santhera Pharmaceuticals, the NIH (U01NS043127-09 [Consultant], U01NS043127-09 [Consultant], 1K23 NS060949-02 [Mentor], and 5K23 NS052487-05 [Mentor]), and the Michael J Fox Foundation; and directs the Rush Parkinson's Disease Research Center, which receives support from the Parkinson's Disease Foundation. Dr. Stebbins has served/serves on the editorial boards of Movement Disorders and the Journal of Clinical and Experimental Neuropsychology; and receives research support from the NIH (NIA AG09466 [Co-PI] and NINDS N057514 [Coinvestigator]), the American Cancer Society, the Michael J. Fox Foundation for Parkinson Research, and the Fragile-X Foundation.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.

1) NMDA receptor antibodies and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Drs. Harald Pruss, Josep Dalmau and Klaus-Peter Wandinger about their paper on NMDA receptor antibodies. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about acute intermittent porphyria as a mimic of Guillain-Barré syndrome. In the next part of the podcast Dr. Beau Bruce interviews Dr. Ted Burns for the next part of our discussion on diagnostic testing for myasthenia gravis for our Lesson of the Week. Over the subsequent three weeks, we will continue to highlight other areas of the frontal cortex. The participants had nothing to disclose except Drs. Dalmau, Wandinger, Overman, and Burns. Dr. Dalmau has received royalties from a patent re: Ma2 autoantibody test and has patents pending re: NMDA and GABAB receptor autoantibody tests (license fee payments received from EUROIMMUN AG); and receives research support from funding from EUROIMMUN AG and the NIH/NCI [RO1CA107192 (PI) and RO1CA89054-06A2 (PI)].Dr. Wandinger is a full-time employee of and holds stock in EUROIMMUN AG. Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) Acute ischemic stroke and 2) Topic of the month: Neuro-muscular disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Ms. Elizabeth Mostofsky about her paper on acute ischemic stroke onset. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about Guillain-Barré in patients with HIV infection. In the next part of the podcast Dr. Beau Bruce interviews Dr. Ted Burns about diagnosis of myasthenia gravis for our Lesson of the Week. Over the next subsequent four weeks, we will highlight neuro-muscular disease. The participants had nothing to disclose except Ms. Mostofsky, Overman, and Burns. Ms. Mostofsky receives research support from the NIH/NIAID (T32-A1007535-11).Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) Pneumococcal meningitis and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Bart Nathan interviews Drs. Matthijs Brouwer and Diederik van de Beek about their paper on pneumococcal meningitis. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about REM sleep behavior disorder in the synucleinopathies. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow for the last part of our discussion on bedside testing of the frontal lobes for our Lesson of the Week. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Van de Beek, Overman, and Burns. Dr. van de Beek has received research support from The Netherlands Organization for Health Research and Development and the Academic Medical Center.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).

1) Non-convulsive status epilepticus and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Alex Menze interviews Dr. Nick Johnson about his paper on non-convulsive status epilepticus. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about hallucinations in dementia with Lewy bodies. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow for the next part of our discussion on areas of the frontal cortex for our Lesson of the Week. The participants had nothing to disclose except Drs Overman and Burns.

1) Mild Alzheimer disease and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Geoffrey Kerchner about his paper on mild Alzheimer disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about MRI findings in idiopathic intracranial hypertension. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow for the next part of our discussion on the orbitofrontal cortex for our Lesson of the Week. Over the subsequent two weeks, we will continue to highlight other areas of the frontal cortex. The participants had nothing to disclose except Drs. Kerchner, Overman, and Burns.

1) Falls in Parkinson disease and 2) Topic of the month: Bedside testing of the frontal lobes. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Tiffini Voss interviews Dr. Kathy Chung about her paper on reducing falls in Parkinson disease. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about stroke in neurocysticercosis. In the next part of the podcast Dr. Ted Burns interviews Dr. Russ Swerdlow about dorsolateral prefrontal cortex for our Lesson of the Week. Over the next subsequent three weeks, we will highlight bedside testing of the frontal cortex. The participants had nothing to disclose except Drs. Voss, Chung, Overman, and Burns. Dr. Chung has received research support from a VA Career Development Award.Dr. Voss has received research support from the University of Rochester for Clinical Monitor for Phase III clinical trial.Dr. Overman serves as Deputy Editor on the Neurology® Resident and Fellow Section editorial team and the Neurology® Podcast Committee.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).