Neurology® Podcast

1) HIV associated motor neuron disease: HERV-K activation and response to anti-retroviral therapy 2) e-Pearl topic: Ataxia with vitamin E deficiency3) Topic of the month: Neurology Today story on functional outcomes of pre-hospital thrombolysis in a mobile stroke treatment unit compared with conventional careThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Avindra Nath about his paper on human endogenous retrovirus-K in amyotrophic lateral sclerosis with HIV infection and response to treatment with anti-retroviral drugs. Dr. Sarah Wesley is reading our e-Pearl of the week about ataxia with vitamin E deficiency. In the next part of the podcast Dr. Andy Southerland interviews Prof. Heinrich Audebert about a Neurology Today story on the topic of functional outcomes of pre-hospital thrombolysis in a mobile stroke treatment unit compared with conventional care.DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Nath serves as Associate Editor for Journal of Neurovirology; has patents for Tat as an immunogen, Diosgenin for Treatment of Neurodegenerative Diseases; Role of Kv Channels in Neuroregeneration and Protection; Role of Lominoid compounds as neuroprotective agents; Tat ELISA; and receives research support from the NIH.Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium for improving treatment times for rapid evaluation of acute stroke via mobile telemedicine;" and gave legal expert review. Prof. Audebert serves as Associate Editor for Frontiers of Teleneurology; is a consultant for Lundbeck Inc., Roche, Bayer Schering Pharma, Pfizer Inc; received speaker honoraria from Takeda Pharmaceutical Company Limited, Boehringer Ingelheim, Lundbeck Inc., Bayer Schering Pharma, UCB, Sanofi-aventis, Pfizer Inc, Bristol-Myers Squibb and EverNeuropharma; participated in an expert meeting launched by Lundbeck Inc. in order to estimate the target population for Desmoteplase; receives research support from the Technology Foundation Berlin and the Berlin Investment Bank with co-financing by the European Union, and Center for Stroke Research Berlin, funded by the German Federal Ministry of Education and Research.

1) Calcium supplementation and risk of dementia in women with cerebrovascular disease2) e-Pearl topic: MGMT promoter methylation in glioblastoma3) Topic of the month: Neurology Today story on a new brain map identifying previously unidentified brain areas and what it means for neurologyThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Silke Kern about her paper on whether calcium supplementation was associated with the development of dementia in women with cerebrovascular disease. Dr. Sarah Wesley is reading our e-Pearl of the week about MGMT promoter methylation in glioblastoma. In the next part of the podcast Dr. Ted Burns interviews Dr. Matthew Glasser about a Neurology Today story on the topic about a new brain map identifying previously unidentified brain areas and what it means for neurology.DISCLOSURES: Dr. Jeff Burns serves on the editorial board for Journal of Alzheimer's Disease; receives royalties for the publications of Early diagnosis and treatment of mild cognitive impairment and Dementia: An atlas of investigation and diagnosis; is a consultant for PRA International and receives research support from the NIH, Alzheimer's Drug Discovery Foundation, Elan, Janssen Pharmaceuticals Inc., Wyeth, Pfizer Inc, Novartis Pharmaceuticals Ltd, Danone, Avid Radiopharmaceuticals, Merck Serono and for clinical trials.Dr. Kern serves as Associate Editor for Journal of Alzheimer`s disease.Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.

1) Reducing costs while enhancing quality of care in MS2) What's Trending: Interview with Lyell Jones about the topic of the Axon Registry and how it interfaces with practice and reimbursement this is part 2 with part 1 appearing last month 3) Topic of the month: Neurology Today story on the AAN Guideline published in Neurology on the topic of recurrent stroke with patent foramen ovaleThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Mark Keegan interviews Dr. Ilya Kister about his paper on the various approaches neurologists may contribute to cost containment while maintaining and enhancing the quality of MS care. Dr. Andy Southerland is interviewing Dr. Lyell Jones for our "What's Trending" feature of the week about the topic of the Axon Registry and how it interfaces with practice and reimbursement. This is part 2 with part 1 appearing last month. In the next part of the podcast Dr. Bryan Eckerle interviews Dr. Steven Messe about a Neurology Today story on the AAN Guideline published in Neurology on the topic of recurrent stroke with patent foramen ovale.DISCLOSURES: Dr. Keegan serves as an editorial board member of Multiple Sclerosis and Related Disorders; served as Chief Editor of eMedicine; receives royalties from the publication of the book: Common Pitfalls in Multiple Sclerosis and CNS Demyelinating Diseases: Case-Based Learning; is a consultant for Novartis, Bristol-Meyers Squibb and Bionest; receives research support from Terumo BCT.Dr. Kister serves on the MS Franchise Data Generation advisory board for Biogen Idec and advisory board for Genentech, Inc.; received a one-time consulting fee from Biogen Idec; received research support from Biogen-Idec, Merck Serono, Novartis, Genzyme Corporation; Guthy-Jackson Charitable Foundation and National Multiple Sclerosis Society.Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium for improving treatment times for rapid evaluation of acute stroke via mobile telemedicine;" and gave legal expert review. Dr. Messe received publishing royalties from UpToDate; received compensation from GlaxoSmithKline for consulting on protocol development for a trial of a neuroprotectant in high risk surgery; received research support from GlaxoSmithKline, Bayer Schering Pharma, WL Gore and the NIH.

1) Anti-LGI1 encephalitis: Clinical syndrome and long-term follow-up2) What's Trending: Interview with Ben Utecht about his recently published book titled: Counting the Days While My Mind Slips Away: A Love Letter to My Family3) Topic of the month: Neurology Today story about NEJM published paper on thymectomy for patients with myasthenia gravisThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Lara Marcuse interviews Dr. Maarten Titulaer about his paper on the clinical features and long-term follow-up of anti-LGI1 encephalitis. Dr. Ted Burns is interviewing Mr. Ben Utecht for our "What's Trending" feature of the week about his recently published book titled: "Counting the Days While My Mind Slips Away: A Love Letter to My Family." In the next part of the podcast Dr. Ted Burns interviews Dr. Gil Wolfe about a Neurology Today story on the topic of thymectomy for patients with myasthenia gravis.DISCLOSURES: Dr. Titulaer serves on the scientific advisory board for MedImmune; serves as an editorial board member for Neurology®: Neuroimmunology & Neuroinflammation; received funding for travel from Sun Pharma; receives research support from Netherlands Organization for Scientific Research, Dutch Epilepsy Foundations and ErasmusMC fellowship.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Mr. Ben Utecht receives honoraria from the American Academy of Neurology and the American Brain Foundation, Spokesperson Agreement.Dr. Wolfe serves as an Associate Editor of Muscle and Nerve; serves on the scientific advisory board for Grifols, Baxalta, Argen X and UCB; receives honoraria for serving on the speakers' bureau of Grifols and Baxalta; receives research support from CSL Behring.

Interviews on evaluation of the anoxic brain injury patient.

1) Editorial Titled: The Terrorist inside My Husband's Brain2) e-Pearl topic: X-linked myopathy with excessive autophagy3) Topic of the month: Neurologic prognosis following cardiac arrestThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Mrs. Susan Schneider Williams about her editorial on learning to deal with her husband's (Robin Williams) Lewy Body disease. Dr. Adam Numis is reading our e-Pearl of the week about X-linked myopathy with excessive autophagy. In the next part of the podcast Dr. Andy Schomer concludes his interview with Dr. Eelco Wijdicks about prognostic models and clinical findings of myoclonus.DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Mrs. Schneider Williams serves on the board of directors for the American Brain Foundation.Dr. Numis serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Wijdicks receives royalties from the publication of several books.

1) Influence of sodium consumption and associated knowledge on post-stroke hypertension in Uganda2) e-Pearl topic: Transient cerebral arteriopathy3) Topic of the month: Neurologic prognosis following cardiac arrestThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Justin Sattin interviews Dr. Larry Goldstein about his paper on the influence of sodium consumption and its associated knowledge on post-stroke patients with and without a history of hypertension in Uganda. Dr. Adam Numis is reading our e-Pearl of the week about transient cerebral arteriopathy. In the next part of the podcast Dr. Andy Schomer continues his interview with Dr. Eelco Wijdicks about the ancillary testing that is done in patients with cardiac arrest.DISCLOSURES: Dr. Goldstein serves as an editorial board member of Neurology®, Emergency Medicine, Cardiology Today and Stroke; serves as an Associate Editor for Cerebrovascular Diseases; serves on the scientific advisory board for Daichi Sanyo, Merz, Roche and Pfizer Inc; is a consultant for Artemida, Nestle and Stroke Hospitalization in Elderly with Medicare; receives honoraria from serving on the scientific advisory board of Pfizer Inc; receives royalties from the publication of the books: Screening for Asymptomatic Carotid Stenosis, Use and Utility of Stroke Scales and Grading Sysytems and Henry Stewart Talks, Secondary Stroke Prevention; receives research support from Stroke Hospitalization in Elderly with Medicare and the NIH.Dr. Numis serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Wijdicks receives royalties from the publication of several books.

1) Cortical superficial siderosis: Prevalence and biomarker profile in a memory clinic population2) What's Trending: Interview with Lyell Jones about Axon Registry and how it interfaces with practice and reimbursement (Part 1)3) Topic of the month: Neurologic prognosis following cardiac arrestThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Chris Tarolli interviews Dr. Sara Shams about her paper on the prevalence and biomarker profile of cortical superficial siderosis in a consecutive memory clinic population. Dr. Andy Southerland is interviewing Dr. Lyell Jones for our "What's Trending" feature of the week about the topic of the Axon Registry and how it interfaces with practice and reimbursement. This is part 1 with part 2 appearing next month. In the next part of the podcast Dr. Andy Schomer continues his interview with Dr. Eelco Wijdicks about the timing of the clinical examination of a patient following cardiac arrest.DISCLOSURES: Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Southerland serves as Podcast Deputy Editor for Neurology; receives research support from the American Heart Association-American Stroke Association National Clinical Research Program, American Academy of Neurology, American Board of Psychiatry and Neurology, Health Resources Services Administration and the NIH; has a provisional patent application titled: "Method, system and computer readable medium for improving treatment times for rapid evaluation of acute stroke via mobile telemedicine;" and gave legal expert review. Dr. Wijdicks receives royalties from the publication of several books.

1) Neurology® Clinical Practice: Incidence of meningeal enhancement on brain MRI secondary to lumbar puncture2) What's Trending: Interview with Robert Gross about his editorial on the trial article format being published this week3) Topic of the month: Neurologic prognosis following cardiac arrestThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jonathan Perk interviews Dr. Sarah Wesley about her Neurology® Clinical Practice paper on the unexplained meningeal enhancement after lumbar puncture. Dr. Ted Burns is interviewing Dr. Robert Gross for our "What's Trending" feature of the week about his editorial on the trial article format being published this week in Neurology. In the next part of the podcast Dr. Andy Schomer interviews Dr. Eelco Wijdicks about the treatment of cardiac arrest and hypothermia management.DISCLOSURES: Dr. Wesley serves on the editorial team for the Neurology® Resident and Fellow Section.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Gross receives support for educational endeavors from the University of Rochester Medical Center's Clinical and Translational Science Award from the NIH, since his appointment as Editor-in-Chief in 2009, he has ceased participation in industry-sponsored clinical trials and speakers' bureaus; receives an honorarium from AAN as Editor-in-Chief of Neurology®.Dr. Wijdicks receives royalties from the publication of several books.NO CME WILL BE OFFERED THIS WEEK.

Zika virus interviews