AHA 2022, Part 2: IRONMAN, ECMO-CS, CTS-AMI, and PROGRESSIVE AF are the trials John Mandrola, MD, reviews in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I. Pushback on PROMINENT

Zimerman Thread: https://twitter.com/AndreZimerman/status/1593019800036708353

II. IRONMAN

IRONMAN Galvanizes Case for IV Iron Repletion in Heart Failure

https://www.medscape.com/viewarticle/984030

Is Iron Replacement in Heart Failure Worth the Trouble?

https://www.medscape.com/viewarticle/983622

- Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial https://doi.org/10.1016/S0140-6736(22)02083-9

III. ECMO-CS

Avoid Routine Early ECMO in Severe Cardiogenic Shock: ECMO-CS

https://www.medscape.com/viewarticle/983618

- Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock: Results of the ECMO-CS Randomized Clinical Trial https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.062949

- Venoarterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock and Cardiac Arrest https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.118.004905

IV. CTS-AMI

Chinese Herbal Medicine May Offer Benefits in STEMI: CTS-AMI

https://www.medscape.com/viewarticle/983619

V. PROGRESSIVE AF

First-Line AF Ablation Cuts Risk of Progression vs Drug Therapy

https://www.medscape.com/viewarticle/983882

Role of Ablation Type and Risk Factors in Paroxysmal AF: PROGRESSIVE-AF Interview https://www.medscape.com/viewarticle/983474

- Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation

https://www.nejm.org/doi/full/10.1056/nejmoa2029980

- Progression of Atrial Fibrillation after Cryoablation or Drug Therapy

https://www.nejm.org/doi/10.1056/NEJMoa2212540

- Natural History of Subclinical Atrial Fibrillation Detected by Implanted Loop Recorders

https://pubmed.ncbi.nlm.nih.gov/31779791/

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