OPENPediatrics

In this World Shared Practice Forum podcast, we discuss the Pediatric Sepsis Data CoLaboratory (Sepsis CoLab), an international open data-sharing network to address pediatric sepsis mortality and morbidity. Drs. Kissoon, Ansermino, and Akech discuss the challenges related to the collection and sharing of data in a global context, the latest advancements in sepsis research and treatment, and how they believe this work will drive better patient outcomes.

LEARNING OBJECTIVES

- Recognize the role of the Sepsis CoLab in global sepsis care

- Describe the challenges and strategies for data sharing in healthcare

- Summarize the importance of standardized data collection in sepsis research

- Discuss some specific examples of how data can be used to support initiatives to improve the care of children with sepsis

AUTHORS

Niranjan "Tex" Kissoon, MBBS, FRCP(C), MCCM, FACPE

Professor, Department of Pediatrics,

University of British Columbia,

Investigator, BCCH Research Institute

President, Global Sepsis Alliance

Institute for Global Health

BC Children's Hospital and BC Women's Hospital & Health Centre

Mark Ansermino, MBBCh

Professor

University of British Columbia

Executive Medical Director for Global Health

BC Children's Hospital

Samuel Akech, MD,

Consultant Pediatrician & Epidemiologist

KEMRI-Wellcome Trust

DATE

Initial publication date: October 21, 2024.

ADDITIONAL RESOURCES

Sepsis CoLab: https://wfpiccs.org/pediatric-sepsis-colab/

Pediatric Sepsis CoLab Membership Application: https://rc.bcchr.ca/redcap/surveys/?s=EDCYL7AC79

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: [email protected]

CITATION

Kissoon NT, Ansermino JM, Akech S, Wolkbrink TA. Improving Sepsis Care: A Data-Driven Approach. 10/2024. OPENPediatrics. https://soundcloud.com/openpediatrics/improving-sepsis-care-a-data-driven-approach-openpediatrics.

In this Complex Care Journal Club podcast episode, Dr. Renee Turchi discusses an intervention study to improve emergency preparedness for families with children and youth with special health care needs. She describes the multiple community partners involved in intervention development, key insights gained while conducting the study, and next steps from this work.

SPEAKER

Renee M. Turchi, MD, MPH, FAAP

Professor and Chair of Pediatrics,

Pediatrician in Chief

St. Christopher's Hospital for Children

HOST

Emily Goodwin, MD

Clinical Associate Professor of Pediatrics,

University of Missouri Kansas City School of Medicine

Pediatrician, General Academic Pediatrics Beacon Program,

Children’s Mercy Kansas City

DATE

Initial publication date: October 7, 2024.

JOURNAL ARTICLE

Griffin JS, Hipper TJ, Chernak E, Berhane Z, Davis RK, Popek L, Kurapati P, Kim J, Turchi RM. A Virtual Home Preparedness Intervention Centered on Children and Youth With Special Health Care Needs. Acad Pediatr. 2024 Jun 10:S1876-2859(24)00167-0. doi: 10.1016/j.acap.2024.06.002. Epub ahead of print. PMID: 38866363. https://www.academicpedsjnl.net/article/S1876-2859(24)00167-0/fulltext

OTHER REFERENCES

Hipper TJ, Davis R, Massey PM, Turchi RM, Lubell KM, Pechta LE, Rose DA, Wolkin A, Briseño L, Franks JL, Chernak E. The Disaster Information Needs of Families of Children with Special Healthcare Needs: A Scoping Review. Health Secur. 2018 May/Jun;16(3):178-192. doi: 10.1089/hs.2018.0007. Epub 2018 Jun 8. PMID: 29883200; PMCID: PMC11015856. https://pubmed.ncbi.nlm.nih.gov/29883200/

TRANSCRIPT

https://op-docebo-images.s3.amazonaws.com/Transcripts/Preparing+for+Emergencies+Planning+and+Partnerships+with+Families_Turchi_100824.pdf

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: [email protected]

CITATION

Turchi RM, Goodwin EJ. Preparing for Emergencies: Planning and Partnerships with Families. 10/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/preparing-for-emergencies-planning-and-partnerships-with-families.

In this World Shared Practice Forum Podcast, Drs. Adrienne Randolph and Aaron Bodansky explore the groundbreaking research findings that uncover the pathophysiological mechanism behind multisystem inflammatory syndrome in children (MIS-C). These findings shed light on the characteristic immune response of patients who develop MIS-C, and provide insight into the development of post-infectious auto-immune disease phenotypes.

LEARNING OBJECTIVES

- Describe the pathophysiology of MIS-C, including the clinical features and molecular immune response

- Describe the immune dysregulation that results in MIS-C, including the role of autoantibodies and T-cell responses

- Identify the potential connections between SARS-CoV-2 infection and the development of autoimmune responses

- Recognize the implications of the study findings for other related conditions such as long COVID and sepsis

AUTHORS

Adrienne Randolph, MD, MSc

Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine

Boston Children's Hospital

Professor of Anaesthesia and Pediatrics

Harvard Medical School

Aaron Bodansky, MD

Assistant Professor

Pediatric Critical Care

University of California, San Francisco School of Medicine

DATES

Initial publication: September 24, 2024.

ARTICLES REFERENCED

Bodansky A, Mettelman RC, Sabatino JJ Jr, et al. Molecular mimicry in multisystem inflammatory syndrome in children. Nature. 2024;632(8025):622-629. doi:10.1038/s41586-024-07722-4.

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: [email protected]

CITATION

Randolph AG, Bodansky A, Burns JP. Unveiling MIS-C's Immune Response: Molecular Mimicry. 09/2024. OPENPediatrics. https://soundcloud.com/openpediatrics/unveiling-mis-cs-immune-response-molecular-mimicry-by-a-randolph-and-a-bodansky-openpediatrics

In this Complex Care Journal Club podcast episode, Ms. de Pins and Dr. Lin discuss a quality improvement initiative to standardize post-visit written communication in a multidisciplinary clinic. They describe stakeholder involvement in defining project goals, effective interventions to reduce the use of medical jargon in after-visit summaries, and next steps from this work.

SPEAKERS

Agathe de Pins, BSc, MSc

Medical Student

Icahn School of Medicine at Mount Sinai

Elaine Lin, MD

Co-Director, Cerebral Palsy and Spasticity Center

Pediatrician, Complex Care Service,

Boston Children's Hospital

HOST

Kristina Malik, MD

Assistant Professor of Pediatrics,

University of Colorado School of Medicine

Medical Director, KidStreet

Pediatrician, Special Care Clinic,

Children's Hospital Colorado

DATE

Initial publication: September 9, 2024.

JOURNAL ARTICLE

de Pins AM, Adu-Amankwah D, Shadman KA, Hess SM, Elaiho CR, Butler LR, Ranade SC, Shah BJ, Fields R, Lin EP. A Quality Improvement Project to Improve After-visit Summary Patient Instructions in a Pediatric Multidisciplinary Neuromuscular Program. Pediatr Qual Saf. 2024 Jul 10;9(4):e743. doi: 10.1097/pq9.0000000000000743. PMID: 38993270; PMCID: PMC11236396.

OTHER REFERENCES

Gidengil C, Parast L, Burkhart Q, Brown J, Elliott MN, Lion KC, McGlynn EA, Schneider EC, Mangione-Smith R. Development and Implementation of the Family Experiences With Coordination of Care Survey Quality Measures. Acad Pediatr. 2017 Nov-Dec;17(8):863-870. doi: 10.1016/j.acap.2017.03.012. Epub 2017 Mar 31. PMID: 28373108.

Hess SM, Adu-Amankwah D, Elaiho CR, Butler LR, Ranade SC, Shah BJ, Shadman K, Fields R, Lin EP. Qualitative feedback from caregivers in a multidisciplinary pediatric neuromuscular clinic. J Pediatr Rehabil Med. 2024;17(2):237-246. doi: 10.3233/PRM-230011. PMID: 38427510; PMCID: PMC11306999.

TRANSCRIPT

https://op-docebo-images.s3.amazonaws.com/Transcripts/Drop+the+Jargon_Lin+and+de+Pins_090924.pdf

Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: forms.gle/Bdxb86Sw5qq1uFhW6

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: [email protected]

CITATION

de Pins AM, Lin EP, Malik K. Drop the Jargon: Improving Written Communication to Families After Multidisciplinary Care. 9/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/drop-the-jargon-improving-written-communication-to-families-after-multidisciplinary-care

This podcast discusses anesthetic considerations for patients with unrepaired tetralogy of Fallot who are undergoing non-cardiac surgeries.

LEARNING OBJECTIVES

Upon listening to this podcast, learners will be able to:

- Explain preoperative considerations

- Provide an anesthetic management plan

- Describe specific non-cardiac surgical procedures and the considerations that need to be addressed when performing them

- Anticipate the postoperative considerations

AUTHORS

Annette Schure, MD

Senior Associate in Cardiac Anesthesia

Boston Children's Hospital

Assistant Professor of Anesthesia

Harvard Medical School

Christian Refakis, MD

Clinical Fellow

Department of Anesthesiology, Critical Care and Pain Medicine,

Boston Children's Hospital

Robert Soohey

Medical Student

Tufts University School Of Medicine

DATES

Initial publication: September 4, 2024.

Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: [email protected]

CITATION

Refakis C, Marcley S, Soohey R, Marques B, Wolbrink TA, Schure AY. Anesthesia for Non-Cardiac Surgeries: Unrepaired TOF. 09/2024. OPENPediatrics. Podcast: https://soundcloud.com/openpediatrics/anesthesia-for-non-cardiac-surgeries-unrepaired-tof-openpediatrics.

In this World Shared Practice Forum Podcast, experts from three large pediatric hospitals discuss their collaborative care models designed to optimize care for patients undergoing hematopoietic stem cell transplant. This global panel reviews the history, structure, and current state of these models, and offers insight into how clinicians can develop and improve their own collaborative care models.

LEARNING OBJECTIVES

- Identify the importance of collaborative care models for hematopoietic stem cell transplant patients

- Discuss the status of current care models in three pediatric stem cell transplant programs

- Apply insights on how clinicians develop collaborative care models and steps that can be taken to make ongoing improvements

AUTHORS

Asya Agulnik, MD, MPH

Associate Member, St. Jude Faculty

Director, Global Critical Care Program

Director, Euro Regional Program

St. Jude Children’s Research Hospital

Indira Jayakumar, MD

Lead Pediatric Intensivist

Apollo Specialty Cancer Hospitals

Co Convenor- IAP Transplant Critical Care,

Chairman- Pediatric wing, ECMO Society of India

Chennai, Tamil Nadu, India

Leslie Lehmann, MD

Attending Physician, Pediatric Stem Cell Transplant Center

Boston Children's Hospital/Dana Farber Cancer Institute

Associate Professor of Pediatrics

Harvard Medical School

Revathi Raj, MBBS, DCH, PLAB, MRCP, FRCPath

Senior Consultant

Department of Pediatric Hematology and Oncology and Blood and Marrow Transplantation

Apollo Hospitals

Chennai, Tamil Nadu, India

Adrienne Randolph, MD, MSc

Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine

Boston Children's Hospital

Professor of Anaesthesia and Pediatrics

Harvard Medical School

Aimee C. Talleur, MD

Assistant Member, Department of Bone Marrow Transplantation and Cellular Therapy

Fellowship Director, BMTCT Fellowship Program

St. Jude Children's Research Hospital

DATES

Initial publication: August 26, 2024.

ARTICLES REFERENCED

• Zinter MS, McArthur J, Duncan C, et al. Candidacy for Extracorporeal Life Support in Children After Hematopoietic Cell Transplantation: A Position Paper From the Pediatric Acute Lung Injury and Sepsis Investigators Network’s Hematopoietic Cell Transplant and Cancer Immunotherapy Subgroup. Pediatr Crit Care Med. 2022;23(3):205-213. doi:10.1097/PCC.0000000000002865 (13:04)

• St. Jude Global Critical Care program, https://global.stjude.org/en-us/programs/transversal-programs/critical-care.html, Email: [email protected] (25:49)

Please visit: http://www.openpediatrics.org

OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: [email protected]

CITATION

Agulnik A, Jayakumar I, Lehmann L, Raj R, Randolph AG, Talleur AC, Wolbrink TA. Collaborative Care Models to Optimize Care of Hematopoietic Stem Cell Transplant Patients. 08/2024. OPENPediatrics. Podcast https://soundcloud.com/openpediatrics/collaborative-care-models-to-optimize-care-of-hsct-patients-by-t-wolbrink-et-al-openpediatrics.

In this Complex Care Journal Club podcast episode, Dr. Kate Nelson discusses a qualitative study exploring decision-making skills developed by family caregivers of children with medical complexity. She describes the impact of contextual factors and relationships within care teams on decision-making, family partnership in research, and the next steps from this work.

SPEAKER

Kate Nelson, MD, PhD

Staff Pediatrician, Paediatric Advanced Care Team

The Hospital for Sick Children

Scientist

SickKids Research Institute

Assistant Professor

University of Toronto

HOST

Kathleen Huth, MD, MMSc

Pediatrician, Complex Care Service, Division of General Pediatrics

Boston Children's Hospital

Assistant Professor of Pediatrics

Harvard Medical School

DATE

Initial publication date: August 5, 2024.

Journal Club Article

Finlay M, Chakravarti V, Buchanan F, Dewan T, Adams S, Mahant S, Nicholas D, Widger K, McGuire KM, Nelson KE. Learning to Trust Yourself: Decision-Making Skills Among Parents of Children With Medical Complexity. J Pain Symptom Manage. 2024 May 28:S0885-3924(24)00792-9. doi: 10.1016/j.jpainsymman.2024.05.023. Epub ahead of print. PMID: 38810951.

TRANSCRIPT

https://op-docebo-images.s3.amazonaws.com/Transcripts/Choice+and+Voice+Family+Perspectives+on+Decision-making+for+Children+_nelson_080524.pdf

Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: [email protected]

CITATION

Nelson K, Huth K. Choice and Voice: Family Perspectives on Decision-making for Children with Medical Complexity. 8/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/choice-and-voice-family-perspectives-on-decision-making-for-children-with-medical-complexity

This podcast discusses the preoperative, operative, and postoperative considerations for patients undergoing tonsillectomy, including anatomy and pathophysiology, preoperative evaluation, anesthetic management, operative approach, and postoperative care.

LEARNING OBJECTIVES

Upon listening to this podcast, learners will be able to:

• Explain the anatomy and pathophysiology

• Describe key considerations for the preoperative anesthetic evaluation and intraoperative anesthetic management plan

• Review common operative approaches

• Discuss postoperative considerations

AUTHORS

Haley Moulton, BA

MS4

Geisel School of Medicine at Dartmouth

Eelam Adil, MD, MBA, FAAP

Associate

Department of Otolaryngology and Communication Enhancement

Boston Children's Hospital

Assistant Professor of Otolaryngology

Harvard Medical School

Ashish Ankola, MD

Assistant Professor of Pediatrics

Texas Children's Hospital

Sonya Mathews

Pre-Medical Student

Jue Wang, MD

Associate in Perioperative Anesthesia

Department of Anesthesiology, Critical Care and Pain Medicine

Boston Children's Hospital

DATES

Initial publication date: July 10, 2024

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: [email protected]

CITATION

Moulton H, Adil E, Ankola A, Mathews S, Wang JT, Marcley S, McFee AM, Wolbrink TA. Tonsillectomy. 07/2024. OPENPediatrics. Podcast. https://soundcloud.com/openpediatrics/tonsillectomy-openpediatrics

In this Complex Care Journal Club podcast episode, Ms. Bethlyn Vergo Houlihan and Ms. Meg Comeau discuss a qualitative study of the perspectives of families of children with medical complexity on what is needed to promote their quality of life and well-being. They describe the family-led approach to designing and conducting the study, the importance of upholding human dignity as a major theme, and next steps to translate their findings into systems change.

SPEAKERS

Bethlyn Vergo Houlihan, MSW, MPH

Project Director, Principal Investigator

Center for Innovation in Social Work & Health

Boston University School of Social Work

Meg Comeau, MHA

Senior Project Director/Principal Investigator

Center for Innovation in Social Work and Health

Boston University School of Social Work

HOST

Kristina Malik, MD

Assistant Professor of Pediatrics,

University of Colorado School of Medicine

Medical Director, KidStreet

Pediatrician, Special Care Clinic,

Children's Hospital Colorado

DATE

Initial publication date: July 1, 2024.

JOURNAL CLUB ARTICLES

Houlihan BV, Coleman C, Kuo DZ, Plant B, Comeau M. What Families of Children With Medical Complexity Say They Need: Humanism in Care Delivery Change. Pediatrics. 2024 Jan 1;153(Suppl 1):e2023063424F. doi: 10.1542/peds.2023-063424F. PMID: 38165241.

Randolph G, Coleman C, Allshouse C, Plant B, Kuo DZ. Measuring What Matters to Children With Medical Complexity and Their Families. Pediatrics. 2024 Jan 1;153(Suppl 1):e2023063424C. doi: 10.1542/peds.2023-063424C. PMID: 38165239.

TRANSCRIPT

chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://op-docebo-images.s3.amazonaws.com/Transcripts/Upholding+Human+Dignity+for+Children+with+Medical+Complexity+and+their+Families_070124.pdf

Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: https://forms.gle/Bdxb86Sw5qq1uFhW6

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: [email protected]

CITATION

Houlihan BV, Comeau M, Malik K. Upholding Human Dignity for Children with Medical Complexity and their Families. 7/2024. OPENPediatrics. Online Podcast. https://soundcloud.com/openpediatrics/upholding-human-dignity-for-children-with-medical-complexity-and-their-families

This podcast provides an overview of the presentation of inflammatory bowel disease (IBD) and compares it to Crohn's disease and ulcerative colitis phenotypes.

LEARNING OBJECTIVES

By the end of this podcast, the learner will be able to:

• Recognize the clinical presentation of inflammatory bowel disease and compare Crohn's disease and ulcerative colitis phenotypes.

• Plan the diagnostic evaluation of patients with suspected IBD.

• Define treatment goals and list available treatment options.

AUTHORS

Jodie Ouahed, MD, MMSc

Director, VEOIBD Clinic

Attending Physician, Inflammatory Bowel Disease Center, Boston Children's Hospital

Assistant Professor, Harvard Medical School

Lauren Collen, MD

Attending Physician, Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital

Instructor of Pediatrics, Harvard Medical School

DATES

Initial publication: June 25, 2024

Please visit: http://www.openpediatrics.org

OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: [email protected]

CITATION

Collen LV*, Ouahed J*, Brodie K, Wills K, Combs A, Snapper SB. Inflammatory Bowel Disease. 6/2024. OPENPediatrics. Podcast: https://soundcloud.com/openpediatrics/inflammatory-bowel-disease-by-j-ouahed-l-collen-openpediatrics. *These authors contributed equally to this work