How do we know when something it good enough? Close enough that we can use product A instead of product B? Well, that’s the issue we’ve addressed in our methods chat this month (https://adc.bmj.com/content/105/3/304.2) We’ve also looked at what used to be the things that sprang to mind with breathing difficulties; bronchiolitis and asthma. For bronchs - what dose of high flow oxygen (https://adc.bmj.com/content/105/3/304.1)? For asthma - could macrolides save the day (https://adc.bmj.com/content/105/3/306)?