In this episode, host Dr Krystyna De Lange is joined by Dr Ashley Bowden, ACRRM registrar and exercise science graduate, to discuss the growing interest in peptides, particularly those promoted in the fitness and wellness sectors.

Dr Ashley Bowden defines peptides as short chains of amino acids and distinguishes between regulated, TGA-approved peptides (such as insulin and GLP-1 analogues) and unregulated, research-use-only peptides commonly discussed online and in gyms. Exploring the demographics of peptide users in Australia, noting that use extends from athletes to recreational gym users, occupational groups, and young adults influenced by social media trends.

They also addressed the limited evidence for the efficacy and safety of unregulated peptides, highlighting that most claims are based on anecdotal reports rather than robust clinical trials. Associated risks include potential side effects, the dangers of unregulated products, and complications related to injection practices.

Dr Bowden provides a practical harm-minimisation approach for GPs whose patients raise questions about or disclose use of peptides. He stresses the value of a non-judgemental, curious approach to build rapport, assess risks, offer regular monitoring, and support overall patient health, while recognising the ethical complexities faced when evidence is lacking.

Links & Resources:

• Healthy Male article: https://healthymale.org.au/health-article/peptides-australia-what-you-need-know
• Webinar: Understanding the use of androgens, SARMS and peptides by Australian males: https://medcast.com.au/courses/1153

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