When asked to defend their belief in a Creator God, people of faith often turn to the argument that there must be a First Cause - you can't create something out of nothing they say, therefore right at the beginning, someone must have been responsible for the first element from which sprang life.

A new book, "A Universe from Nothing", by the American theoretical physicist Lawrence Krauss, turns this argument on its head. Not only can something arise out of nothing, but something will always arise out of nothing because physics tells us that nothingness is inherently unstable.

The book has made an enormous impact in the States, making the New York Times' best sellers list, and it prompted Richards Dawkins to observe that it was "Potentially the most important scientific book with implications for atheism since Darwin".

So does it knock the argument for God on the head? Are physics and God irreconcilable?

Joining Ernie to discuss whether modern physics leaves any room for God are Dr John Lennox, Professor of Mathematics at the University of Oxford, Dr Usama Hasan, Senior Lecturer at Middlesex University and a part time Imam, and Dr Mark Vernon, Honorary Research Fellow at Birkbeck College, London who has degrees in physics, theology and philosophy.