In this episode of The Good GP, host Dr Tim Koh is joined once again by Dr Linny Kimly Phuong, a paediatric infectious diseases physician, researcher, and academic tutor, to discuss Pneumococcal Disease. Being the subject of her PhD, Dr Phuong brings her extensive knowledge and experience on this topic.

Dr Phuong outlines the different clinical manifestations of Pneumococcal Disease, dividing them into invasive and non-invasive categories. Non-invasive diseases include otitis media and sinusitis, while invasive diseases can result in conditions like complicated pneumonia, meningitis, bacteremia, bone and joint infections, endocarditis, and peritonitis.

Discussing the significance of the strep pneumoniae bacteria, which is commonly found in the nasopharynx of healthy individuals. Dr Phuong explains the switch from carriage to disease manifestation and highlights the risk factors for invasive Pneumococcal Disease, including extremes of age, immunocompromise, chronic health conditions, and certain lifestyle factors.

They then turn to pneumococcal vaccines, and the differences between conjugate and polysaccharide vaccines, their valencies, and their impact on clinical practice. Dr Phuong emphasises the importance of vaccination in reducing morbidity and mortality related to Pneumococcal Disease, particularly in young children and older adults.

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