This episode we celebrate the release of the new Therapeutic Guidelines - Antibiotic! Jane and Kristin are joined by Senior Editor Jess Gibney and Dr Emily Tucker, ID Physician from Flinders Medical Centre to discuss what's new and what's changed.

Things we learnt include:

• How to say Happy Easter in Greek

• How Therapeutics Guidelines put its expert groups together

• The process of updating guidelines

• Why TG is no longer being published in hard copy

• Changes to surgical prophylaxis recommendations

• The new inclusion of intravenous Amoxicillin/Clavulanate as a treatment option, and the behind the scenes discussion around the use of this agent, including dosing controversies

• New advice for Ceftriaxone dosage

• The choice to expand advice around "watching and waiting" and when NOT to use antibiotics

• A new approach to the classification of community acquired pneumonia

• Significant changes to advice around antibiotic allergies (side chains!)

• Some challenges in updating the paediatric section of the Guidelines

Visit the Therapeutic Guidelines at http://www.tg.org.au