Real Life Pharmacology - Pharmacology Education for Health Care Professionals

On this episode of the Real Life Pharmacology Podcast, I discuss bumetanide pharmacology, adverse effects, and drug interactions.

Bumetanide is a loop diuretic and it is critical to monitor renal function and electrolytes with this medication.

Ototoxicity is a rare adverse effect that is dose-dependent and can be worsened by aminoglycosides.

It is critical to look for drugs that can worsen edema when using bumetanide to ensure that we avoid the prescribing cascade.

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On this episode, I discuss oxycodone pharmacology, adverse effect, pharmacokinetics, and drug interactions.

Oxycodone is broken down by CYP3A4 and CYP2D6. I discuss this further on the podcast and how interactions may alter concentrations.

When a patient stops taking oxycodone after being on it for some time, you must recognize common symptoms of withdrawal.

Oxycodone comes as in an extended-release and immediate-release oral formulation.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

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BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode of the Real Life Pharmacology podcast, I explore doxycycline pharmacology, adverse effects, and drug interactions.

Doxycycline can be bound by numerous minerals like calcium, magnesium, and iron. Coadministration can lead to reduced concentrations.

Sun sensitivity is a really important adverse effect that can be caused by doxycycline. Be sure to educate your patients.

Doxycycline can be used as an alternative to beta-lactams and macrolides in the management of community-acquired pneumonia.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode, I discuss tolterodine pharmacology, adverse effects, and drug interactions.

Tolterodine (Detrol) is an anticholinergic medication used to manage the symptoms of overactive bladder.

Tolterodine’s anticholinergic activity can lead to a significant number of adverse effects like dry mouth, dry eyes, constipation, and urinary retention.

Elderly patients may be at greater risk for anticholinergic adverse effects from tolterodine compared to younger patients.

Tolterodine can have additive effects from other anticholinergics like diphenhydramine or TCAs which enhance its potential for side effects.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode, I discuss clarithromycin pharmacology, adverse effects, and drug interactions.

Clarithromycin is a macrolide antibiotic that can be used for many similar indications as azithromycin.

Clarithromycin has numerous drug interactions as it can inhibit CYP3A4. This limits its use in practice.

Clarithromycin can be used in the treatment of H. pylori in combination with other antibiotics and a PPI.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode, I discuss azathioprine pharmacology, adverse effects, monitoring parameters, and drug interactions.

Azathioprine is classified as an immunosuppressive agent so it is naturally going to be used for autoimmune type disorders and transplantation.

Azathioprine has a boxed warning for myelosuppression. I talk more about this in the episode.

Genetic testing is recommended by the AGA prior to the use of azathioprine. I discuss which tests might be helpful to reduce the risk of toxicity.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode, I discuss amitriptyline pharmacology, adverse effects, and drug interactions.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode of the podcast, I discuss my approach and strategies to handle grapefruit juice interactions.

Grapefruit juice causes drug interactions by inhibiting the CYP enzyme system. More specifically, it inhibits CYP3A4 which is responsible for the breakdown of many medications.

Quantity is always an important consideration when assessing grapefruit juice interactions. The more that is taken, typically, the more drug concentrations will be affected.

It is important to assess the use of grapefruit juice when your patient has a history of cardiovascular disease, cardiac conditions, pain, mental health disease, or gout as some medications used to treat these diseases can interact with grapefruit juice.

If you are looking for more content on drug food interactions, be sure to check out my book in the links below.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode, I cover pantoprazole pharmacology, adverse effects, and drug interactions.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating

On this episode, I discuss rosuvastatin pharmacology, adverse effects, drug interactions and pharmacokinetics.

Rosuvastatin is a hydrophilic statin which differs from some of the most commonly used statins like simvastatin and atorvastatin.

Rosuvastatin is minimally affected by CYP3A4 drug interactions so that is a small potential advantage over simvastatin and atorvastatin.

At dosages of 20-40 mg, rosuvastatin is considered a high intensity statin and can bring down LDL by over 50%.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Nursing Pharmacology Review Course

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating