A 2025 Anesthesiology meta-analysis shows that the best pain control after total hip arthroplasty comes from combining regional anesthesia with local infiltration analgesia (LIA). While LIA alone is effective, adding a quadratus lumborum or pericapsular nerve group (PENG) block significantly improves pain relief, reduces opioid use, and preserves mobility. The takeaway: stop choosing between techniques — regional + local is the new gold standard for hip surgery analgesia.

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