ALT/WDLPS are fatty tumors most commonly occurring in the extremity and retroperitoneum that have a relatively indolent behavior, but a strong predilection for local recurrence. In this episode of SurgOnc Today®, Episode 2 of this series on ALT/WDLPS, Brian Kadera, MD, John Mullinax, MD, Giorgos Karakousis, MD, and Steven Thorpe, MD, will focus on local management, surgical approaches, and the risks/benefits of radiation in the neoadjuvant/adjuvant setting. We will highlight differences in the natural history of this tumor when it occurs in the extremity versus the retroperitoneum, and touch briefly on the management of local well-differentiated recurrences.