A just-published study found that consuming two or more sugar-sweetened beverages in a day is linked to a doubling of colon cancer risk in women. The research generated dozens of headlines, all warning readers of the potential danger posed by regular soda intake. But a closer look at the study reveals some key limitations that prevent us from drawing any firm conclusions from the data:
* A small sample size: only 109 people out of more than 40,000 developed the disease, making it difficult to establish a correlation between sugar and colon cancer
* Study participants reported their soda consumption using food frequency questionnaires, which many epidemiologists have argued are notoriously unreliable sources of data.
* Many previous studies have failed to find an association between sugar and colon cancer, and some research has even found that it could have a protective effect against the disease.
For these and several other reasons, the new study is somewhat of an outlier and thus worthy of heightened scrutiny, cancer epidemiologist Geoffrey Kabat wrote in a recent article for GLP. But this didn't stop reporters (with the help of the study authors) from speculating about the significance of the paper:
Human beings are so constructed that when we read such a news story, we immediately take the highlighted finding as if it were true and worry that something we had considered relatively harmless—drinking sweetened beverages— could be adversely affecting our health or the health of people close to us. People who have an interest in publicizing this type of result (scientist authors, journal editors, and journalists) know that stories like this provoke a visceral reaction. The logic behind this kind of reporting could be distilled down to the injunction, “Start worrying—details to follow.”
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The problem is much greater than a single eye-grabbing paper, Kabat argued. There is an entire sub-discipline within epidemiology, known as risk-factor epidemiology, that tries to correlate particular chemical exposures with complex diseases like cancer. While not inherently flawed, research in this field is prone to exaggeration and risks misleading the public about the risks they face from food, chemicals and other environmental exposures. As Kabat put it:
Over the years, a number of prominent epidemiologists have criticized risk factor epidemiology and “approaches that abstract single elements … from the complexity of the life and times of people and relate these to a single health outcome.