Surgical clearance, NICM assessment, dueling perspectives on PCI as first-line therapy for angina, GDMT in HFrEF are the topics John Mandrola, MD, discusses in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I. New ACC Peri-operative Guidelines Released

• ACC Guideline document https://www.jacc.org/doi/10.1016/j.jacc.2024.06.013
• J Vasc Surg https://www.jvascsurg.org/article/S0741-5214(21)00335-9/fulltext
• McFalls and colleagues; CARP https://www.nejm.org/doi/full/10.1056/NEJMoa041905

II. NICM – We may be doing it wrong in Selecting ICDs

• JAMA Meta-analysis https://jamanetwork.com/journals/jama/fullarticle/2823869/
• German CMR ICD Trial https://www.clinicaltrials.gov/study/NCT04558723
• BRITISH CMR trial https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/britishusing-cmr-scar-as-risk-indication-tool-in-nicm-and-severe-lvsd/

III. When Should PCI be Used in Chronic Stable CAD?

• Rajkumar and Al-Lamee; PCI First https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.124.011201

• Boden and De Caterina; Meds First https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.124.011268
• ORBITA 10.1016/S0140-6736(17)32714-9
• ORBITA 2 trial https://www.nejm.org/doi/full/10.1056/NEJMoa2310610

IV. GDMT Underuse in HFrEF

• Greene and colleagues https://doi.org/10.1016/j.jchf.2024.08.002
• DAPA HF https://www.nejm.org/doi/full/10.1056/NEJMoa1911303
• RALES https://www.nejm.org/doi/full/10.1056/NEJM199909023411001

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