There are plans to make high dose statins available over-the-counter without a prescription to improve uptake. Currently around two thirds of people likely to benefit most don't take them, but will these plans make a difference? Amyloidosis is a debilitating rare disease that is often missed: Pam tells her amazing story of recovery and Mark meets the specialists helping her. And news about new gene silencing treatments that could transform the outlook for people with other rare conditions too.