Do opiates make pain more bearable than non-steroidals in the emergency department? When you’ve got a really, really painful musculoskeletal injury? Well, listen up to find the answer, and read here: https://adc.bmj.com/content/105/12/1229.1.

And you know that we leave a four-week gap between live-attenuated immunisations, but do we really need to do that, especially with more modern ones? (https://adc.bmj.com/content/105/12/1232)

After wondering about how to define not knowing, we now talk about what levels of certainty we might need in different situations … and, well, it won’t be a spoiler to say “It Depends” (https://adc.bmj.com/content/105/12/1229.2).