I'm joined by Sam Mandel, co-founder of Ketamine Clinics Los Angeles, to break down everything you actually need to know about ketamine therapy. Sam shares what it is, how it works, who it's for, and why it remains one of the most effective and underutilized mental health treatments available today, whether ketamine can be addictive, how it works on treatment resistant depression, how it works differently than traditional antidepressants, why IV infusions are considered the gold standard over lozenges or nasal sprays, what actually happens in your brain during a session, what you can expect to feel, the history of ketamine, how he's seen it changing lives for people with depression, PTSD, anxiety, OCD, postpartum depression, what actually happened to Matthew Perry, and much more.