In this episode, Kayla sits down with Dr. Karan Rajan, who is one of the most followed medical professionals on social media, and he breaks down the gut microbiome like you've never heard before. If you've ever felt bloated after eating fiber, tried keto and felt amazing temporarily, or wondered why your "clean" diet isn't delivering results, this episode is for you.
They talk about why fiber is non-negotiable fuel for your gut bacteria, how to gradually increase intake from 10g to 50g+ daily, and the specific prebiotic fibers that matter most. Dr. Rajan shares his daily eating protocol, explains why prebiotics trump probiotics, and reveals the critical differences between male and female microbiomes. You'll also learn his exact protocols for recovering from antibiotics, healing leaky gut and why fasting activates your gut's self-cleaning system. 

Guest’s socials + website
Instagram: @drkaranrajan
Website: https://www.drkaranrajan.com/

Kayla's social + website:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter: https://x.com/femalelongevity 
Website: https://www.kaylabarnes.com/
Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/
Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Your home could be triggering your allergies and nobody's checking. Dr. Tania Elliott sees patients struggling with reactions that disappear before they can get to the doctor's office. That's why she started doing virtual home tours to find what's really causing the problem.In this episode, Dr. Elliott explains why that new couch smell is actually toxic, how synthetic candles mess with your hormones, and why our obsession with being too clean backfired into an allergy epidemic. She digs into Mast Cell Activation Syndrome, shares why peanut allergies in kids went through the roof after we delayed introducing peanuts, and gives you simple steps to clean up your indoor air. If you're dealing with mystery symptoms or just want to make your home healthier, this conversation is full of practical changes that actually work.Join the most comprehensive female-specific community for health and longevity optimization. After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/checkout/become-a-memberGuest’s website + socials Website: https://www.taniaelliottmd.com/Instagram: https://www.instagram.com/drtaniaelliott/Kayla's social + website:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevity

YouTube: www.youtube.com/@KaylaBarnesLentzWebsite: https://www.kaylabarnes.com/Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Are you planning to get pregnant, currently pregnant, or postpartum? This conversation with dietitian Lily Nichols will change how you think about nutrition during these critical life stages.Lily reveals that over 90% of women have nutrient deficiencies that directly impact fertility, pregnancy outcomes, and postpartum recovery. Most women have no idea they're lacking essential nutrients like protein, iron, zinc, B12, choline, and vitamin A until it's already affecting their hormones and ability to conceive. She explains why you need 7 to 8 months of preconception nutrition to build up nutrient stores before getting pregnant, the Goldilocks body fat percentage for optimal hormone production and fertility and why protein should always be your first priority at every meal plus how much you actually need. She also reveals how nutrient needs skyrocket in the second and third trimester plus postpartum and why vegan diets during pregnancy require serious supplementation and careful planningIf you're in your preconception phase, currently growing a baby, or recovering postpartum, this episode is packed with actionable nutrition advice you can start using today.

Guest’s website + socials

Website: https://lilynicholsrdn.com/

Instagram: https://www.instagram.com/lilynicholsrdn/Kayla's social + website:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevityT

witter: https://x.com/femalelongevity

Website: https://www.kaylabarnes.com/

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/

Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Are you dealing with unexplained fatigue, hormonal imbalances, brain fog, or chronic inflammation that doctors can't figure out?

In this episode, Dr. Jess Peatross explains why so many people are sick with "mystery symptoms" that doctors can't solve. She breaks down the toxins and infections making you sick, how to test for them properly, and her step-by-step "Kill Bind Sweat" detox method. So, if you've been told "it's all in your head" or that your labs are normal but you still feel awful, this episode will give you real answers and a clear path forward.

Guest’s socials + website:Instagram: https://www.instagram.com/dr.jess.md/Website: https://drjessmd.com/

Kayla's social + website:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter: https://x.com/femalelongevity

Website: https://www.kaylabarnes.com

Youtube: www.youtube.com/@KaylaBarnesLentz

Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

When a top surgeon faces his own health collapse, he’s forced to question everything he’s ever believed about medicine. In this gripping conversation, Dr. Darshan Shah reveals how hitting rock bottom led him to uncover the true keys to longevity — from biomarker mastery and advanced testing to the future of AI-driven health and gene therapy.

This episode will make you rethink what it means to live — and how long you can do it.

Join the most comprehensive female-specific community for health and longevity optimization.

After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan.

Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Kayla's social + website:Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter: https://x.com/femalelongevity

Website: https://www.kaylabarnes.com

YouTube: www.youtube.com/@KaylaBarnesLentz

Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Follow Her Female Protocol:

https://www.protocol.kaylabarnes.com

Dr. Shah social + website:

https://www.drshah.com/

Instagram: https://www.instagram.com/darshanshahmd/

YouTube: https://www.youtube.com/darshanshahmd

X: https://x.com/DarshanShah_MD

LinkedIn: https://www.linkedin.com/in/darshanshahmd/

Facebook: https://www.facebook.com/healthhackerMD

Most people think heart disease is just about cholesterol. But what if the real issue is in your genes, your environment, and even your daily stress?

In this episode, I’m joined by Dr. Christopher Davis, a triple board-certified interventional cardiologist who’s redefining what it means to take care of your heart. After years of performing stent procedures, he realized the conventional system was only treating symptoms, not causes. So he made a bold shift from reactive cardiology to a root-cause approach that blends advanced testing, functional medicine, detoxification, and even ancient healing wisdom. We discuss how genetics determine whether saturated fats help or harm you, why cholesterol itself isn’t the enemy, and how inflammation and oxidative stress are the real threats to your arteries. 

If you’ve ever wondered why someone with perfect cholesterol can still have a heart attack, or why your stress levels matter just as much as your diet, this conversation will change how you think about cardiovascular health forever.

Guest’s website + socials:

Website: https://revealvitality.com/christopher-davis/

Instagram: @cjdavismd

Kayla's social + website:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter: https://x.com/femalelongevity 

Website: https://www.kaylabarnes.com/

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/

Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Brain coach Jim Kwik went from being called “the boy with the broken brain” to teaching millions how to unlock their limitless potential. In this episode, he reveals the simple shifts that supercharge focus, memory, and learning speed—helping you read faster, think clearer, and retain more.

Discover why mindset, motivation, and method are the three keys to peak mental performance, and how to apply them in everyday life. Whether you’re an entrepreneur or lifelong learner, this conversation will change the way you use your brain.

Join the most comprehensive female-specific community for health and longevity optimization. After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.

https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Chapters:

00:00 Intro

01:30 Jim Kwik’s story: from “broken brain” to brain coach

07:15 The moment that changed everything 09:20 The Limitless Model: Mindset, Motivation, Methods

19:30 Memory and focus hacks

33:55 Becoming a limitless learner

48:31 Speed reading & overcoming common obstacles

01:00:40 Using AI to enhance, not replace, your brain

01:10:30 10 keys to a limitless brain

01:18:58 Closing challenge & wrap-up

Kayla's social + website:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter: https://x.com/femalelongevity

Website: https://www.kaylabarnes.com

YouTube: http://www.youtube.com/@KaylaBarnesLentz

Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

Jim's social + website:Facebook: https://www.facebook.com/jimkwikofficial/

Instagram: https://www.instagram.com/jimkwik/

TikTok: https://www.tiktok.com/@jimkwik?lang=en

X: https://x.com/jimkwik

Free Brain Tips: https://go.kwikbrain.com/30-tips-yt

A lot of women are tired, busy, and trying to stay healthy. But what if you didn’t need to do everything perfectly to feel good? In this episode, we talk about the key parts of health that matter most. You’ll learn how much sleep your body actually needs, what kind of movement helps you stay strong, how to eat for steady energy, and why your relationships can change your health.

We also talk about real numbers and real habits that work. All you have to do is to learn what truly helps your body stay balanced, strong, and full of energy.

See Kayla's full protocol here: https://www.protocol.kaylabarnes.comTech items mentioned: Pulsetto:  https://pulsetto.sjv.io/raOKYy (use code Kayla10 to save!)

Chapters

00:00:44: Introduction of health pillars and minimum effective dosage.

00:01:44: Benefits of sleep and women's unique sleep needs.

00:05:34: Kayla's personal sleep routine and wind-down practices.

00:08:17: Optimal sleep duration and key sleep hygiene tips.

00:13:30: Analysis of sleep metrics like deep and REM sleep.

00:22:14: Hormonal benefits of sleep, specifically cortisol and melatonin.

00:24:22: Introduction to exercise and Kayla's detailed protocol.

00:30:26: Minimum effective dose for exercise, focusing on Zone 2.

00:34:00: Importance of strength training and general fitness goals.

00:38:07: Understanding body composition, fat mass, and bone density.

00:47:37: Nutrition personalization and metabolic health goals.

00:56:18: Social connection as a pillar of longevity.

Guest’s socials + website

Instagram: @saragottfriedmd

Website: https://saraszalmd.com/

Kayla's social + website:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter: https://x.com/femalelongevity 

Website: https://www.kaylabarnes.com/

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/

Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

Dr. Brad Schoenfeld, PhD is one of the world’s leading researchers on muscle hypertrophy (muscle growth). He is a Professor of Exercise Science at Lehman College in New York, where he directs the Human Performance Laboratory. Over his career, he has published more than 300 peer-reviewed articles, book chapters, and textbooks on resistance training, body composition, and nutrition.

He is the author of Science and Development of Muscle Hypertrophy and The Max Muscle Plan, and has received prestigious honors such as the NSCA Young Investigator of the Year and the Dwight D. Eisenhower Fitness Award. Beyond academia, he has been a personal trainer and natural bodybuilding competitor, which allows him to uniquely bridge cutting-edge science with practical application.

Here's what he knows: the fitness industry has been selling you the wrong story. Not maliciously, but confidently. And most people are paying the price without even realizing it.

In this episode, Brad reveals why so many people are working harder than they need to while missing the basics that matter most. We discuss the beliefs keeping women from reaching their potential, the risks that sneak up when you avoid certain types of training, and what actually determines whether you stay strong and independent decades from now. He also tackles the myths around supplements, workout structure, and whether you're doing enough or too much.

If you're ready to stop spinning your wheels and start training smarter, this conversation will show you exactly where to begin.

Chapters:

00:00 - Meet Dr. Schoenfeld & why strength training is vital for health

07:00 - Metabolic health, bone density & preventing osteoporosis

15:00 - Training for strength, hypertrophy & power (and busting myths)

25:00 - Practical routines: how much volume, soreness, and recovery time

34:00 - Glute growth, exercise variety & women’s training differences

45:00 - Protein, fueling & the truth about creatine

Dr. Schoenfeld’s Social + Website

Website:

https://www.lookgreatnaked.com/

Instagram:

https://www.instagram.com/bradschoenfeldphd/

Kayla's Social + Website

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter: https://x.com/femalelongevity

Website: https://www.kaylabarnes.com

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com

For years, women have been told that birth control or IVF are the only solutions to reproductive issues. Dr. Naomi Whitaker knows that’s not the full story. Through Restorative Reproductive Medicine, she helps women identify the deeper health imbalances that fuel infertility, endometriosis, PCOS, and hormones, and shows how healing the body’s natural rhythms can change everything. 

In this episode, Dr. Whitaker reveals why standard lab ranges are often misleading, how cycle charting can act like a “health report card,” and why bioidentical hormone support is a game changer for energy, mood, and long-term vitality. She also shares her perspective on endometriosis surgery, PCOS subtypes, and the future of reproductive care. If you are tired of one size fits all advice and want science based, patient focused solutions that aim to fix root causes, this conversation gives straightforward clarity and practical next steps.

Chapters:

00:05:22 - Introduction to Restorative Reproductive Medicine

00:08:14 - The evolution of medicine and limitations of traditional research

00:17:24 - Core principles of Restorative Reproductive Medicine (RRM)

00:19:36 - Challenging the concept of "incessant ovulation" as a cancer risk

00:25:27 - Importance of thorough patient intake and cycle charting in RRM

00:33:19 - Practical tips for Creighton Model cycle charting

00:45:27 - The role and importance of bioidentical progesterone in women's health

00:59:05 - Reversing high FSH with DHEA for ovarian longevity

01:10:27 - Comprehensive insulin resistance testing and management strategies

01:43:22 - Surgical options and novel treatments for PCOS

01:55:53 - Adhesion prevention and delicate surgical techniques in pelvic reconstruction

02:19:57 - Understanding endometriosis in Detail

Guest’s socials + website

Instagram: @napro_fertility_surgeon

Website: https://bio.site/napro_fertility_surgeon 

Kayla's social + website:

Instagram: https://www.instagram.com/kaylabarnes/

TikTok: https://www.tiktok.com/@femalelongevity

Twitter: https://x.com/femalelongevity 

Website: https://www.kaylabarnes.com/

Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/

Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member