I’ve always been fascinated by brain health—how we think, feel, and function is deeply tied to how we live our lives. And yet, for so long, cognitive decline has been framed as an inevitable part of ageing. But what if that’s not the full story?

In this Live Well, Be Well episode, I sit down with two of the world’s leading neurologists, Drs. Dean and Ayesha Sherzai to explore the cutting-edge science of brain health, neuroplasticity, and longevity. Their work is revolutionising our understanding of how we can actively shape our cognitive future—and the truth is, we have far more control than we think.

We get into:

✔️ The myth of brain ageing—why decline isn’t inevitable and how we can strengthen our cognition at any age.

✔️ The power of neuroplasticity—how small daily habits can rewire the brain for better focus, memory, and resilience.

✔️The sleep-brain connection. Why deep sleep is the ultimate detox and the number one factor for long-term cognitive health.

✔️Food as medicine for the brain—how the MIND Diet has been shown to reduce Alzheimer’s risk by over 50%.

✔️The real impact of stress on cognition—and how we can train our brains to handle pressure more effectively.

✔️The attention crisis—how social media and technology are rewiring our minds and what we can do to regain control.

Drs. Dean and Ayesha Sherzai are co-directors of the Alzheimer’s Prevention Program at Loma Linda University and the authors of The Alzheimer’s Solution. Their research proves that up to 80% of dementia cases could be prevented—and in this episode, they share the simple but powerful changes we can all make today to build a healthier, sharper brain for life.

This conversation really shifted the way I think about my brain health, and I hope it does the same for you. If you found this episode valuable, please share it—and as always, let me know your thoughts.

🌐 Team Sherzai Website https://thebraindocs.com/

📸 Instagram: https://www.instagram.com/thebraindocs/

Sarah Ann

***

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***

If you enjoyed this episode you might also like:

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How To REWIRE Your Brain and How To Change Your Mind: Professor David Nutt

https://www.youtube.com/watch?v=TWzwn99YySE 

***

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***

Highlights:

Intro (00:00)

Surprising Facts About Brain Health (00:29)

The Brain’s Energy Consumption & Resilience (01:53)

The Importance of Sleep for Brain Health (02:32)

How Much Sleep Do We Really Need? (04:39)

Simple strategies to improve sleep quality (07:08)

The Science Behind Racing Thoughts Before Bed (10:47)

Differences Between Men’s & Women’s Brains (13:36)

Women’s Brain Health & Menopause (15:14)

Preventing Cognitive Decline & Alzheimer’s (23:27)

The best foods for memory and mental clarity (35:47)

Debunking Diet Myths: Berries & Brain Health (41:02)

The Power of Simple Dietary Changes (41:33)

The Importance of Leg Strength & Exercise (46:01)

Omega-3 Fatty Acids: Fish vs. Supplements (49:45)

How your brain can rewire and grow throughout life (56:10)

How social media is affecting focus and cognition (01:03:16)

Practical Tips for Optimising Brain Health (01:10:21)

Key takeaways for a sharper, healthier brain. (01:16:07

***

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Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

Ever wonder why you can’t stop eating certain foods? It’s not just willpower—it's science. Food companies have mastered the art of making ultra-processed foods irresistible, from texture to taste to the way they break down in your body. Even diet sodas, which seem like the perfect fix, could be making things worse. If you think you’re making “healthy” choices, you need to hear this.

Listen to the full episode here.

Watch the full episode on YouTube here.

***

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***

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Dr. Chris Van Tulleken: How Ultra-Processed Foods Are Making Us Sick

https://www.youtube.com/watch?v=6SxK9MFmH4c

***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies 

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***

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What if the secret to living a longer, healthier life wasn’t in a pill, supplement, or biohacking trend—but in your environment, relationships, and daily habits?

In this episode, I sit down with Dan Buettner, National Geographic explorer, bestselling author, and longevity researcher, to break down the science of the Blue Zones—regions of the world where people live the longest and thrive well into their 90s and 100s.

We dive deep into the data-driven habits that contribute to longevity, why your social circle can determine your health, and the biggest myths about aging and diet. Dan also shares his response to recent criticisms about the Blue Zones and reveals new emerging longevity hotspots based on his latest research.

In this episode, we cover:

✔️ The 5 regions in the world where people consistently live the longest

✔️ Why community and social connection are more powerful than willpower

✔️ The ideal longevity diet based on decades of research

✔️ How your environment is the #1 factor in shaping health outcomes

✔️ The biggest longevity myths - and what actually works

✔️ How modern society is eroding these Blue Zone principles - and what we can do about it

Who is Dan Buettner?

Dan Buettner is a National Geographic fellow, New York Times bestselling author, and founder of Blue Zones, a research initiative dedicated to understanding and applying the world’s best practices for longevity. His work has led to policy changes in over 70 cities to improve public health, and his Netflix documentary, Live to 100: Secrets of the Blue Zones, explores these regions in depth.

👉 Connect with Dan Buettner:

• Website: www.bluezones.com
• Instagram: @danbuettner

***

Thank you to my wonderful sponsors! 

OneSkin | Topical Products for Healthy Aging

http://oneskin.co/LWBW 

Use code LWBW for 15% off your first order 

***

If you enjoyed this episode, you might also like:

Live to 100 with Secrets of the Blue Zones: What The Longest Living People Eat Daily | Dan Buettner

https://www.youtube.com/watch?v=UUHR8wwSVIs

Ellen Langer: The Mind Can Slow Down an Aging Body

https://www.youtube.com/watch?v=VGpNMy1VxsY

Most Extreme Anti-Ageing Routine: How To STAY YOUNG Forever & Look 18 Again | Bryan Johnson

https://www.youtube.com/watch?v=6G-Ax76WwXM

***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies 

https://sarahmacklin.substack.com/

Unlock Stress-Busting Recipes: Get My Top 5 Mood-Boosting Meals Now! 🍽️🧘‍♀️ | Click Here to Reduce Stress Deliciously 

https://sarahmacklin.substack.com/

http://bit.ly/3HDuVxj

***

Highlights:

Introduction (00:00)

Blue Zones – Secrets of Longevity (02:39)

Three Essential Habits for a Longer Life (06:59)

The Power of Purpose in Longevity (10:14)

How Volunteering Boosts Well-Being and Self-Worth (14:50)

Lessons from Centenarians: Wisdom for a Longer Life (17:07)

How to Design a Blue Zone Environment (22:17)

Eating for Longevity: Key Dietary Principles (28:33)

Why It’s Hard to Eat Healthy in Today’s Food Landscape (34:05)

Making Nutritious, Affordable Food Accessible in Inner Cities (36:47)

How Modern Life Is Eroding Blue Zones (41:42)

Debunking the Myths and Controversies Around Blue Zones (47:01)

Why Environment Matters More Than Willpower for Longevity (53:14)

The Future of Blue Zones: New Regions and What’s Next (01:00:53)

Closing Thoughts – Living Well, Being Well (01:08:14)

***

Let’s be friends!

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💌 Newsletter: https://sarahmacklin.substack.com/

Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

Letting go isn’t easy, but it’s essential for personal growth and healing. In this clip, Diego Perez, the author and meditation teacher behind Yung Pueblo, shares why trust and repetition are crucial for moving forward. Learn how finding the right tool—like Vipassana meditation—can help you break negative cycles, stop overthinking, and create meaningful change. If you’re struggling to let go of pain, fear, or attachments, this video offers practical steps and inspiration to start your journey.

Listen to the full episode here.

Watch the full episode on YouTube here.

***

Thank you to my wonderful sponsors! 

FREE Ridiculously healthy coffee works well for me.

Use code FREETRIALSARAH for your free trial

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Get a free trial and use code LIVEWELL for 10% off your first website or domain 

***

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Mo Gawdat: How To Transform Stress Into Success

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***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies 

https://sarahmacklin.substack.com/

Unlock Stress-Busting Recipes: Get My Top 5 Mood-Boosting Meals Now! 🍽️🧘‍♀️ | Click Here to Reduce Stress Deliciously 

https://sarahmacklin.substack.com/

http://bit.ly/3HDuVxj

***

Let’s be friends!

📷 Instagram: / sarahannmacklin

📹 Subscribe: / @livewellbewellsarah

🐦 Twitter: / sarahannmacklin

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💌 Newsletter: https://bit.ly/3rUbHyS

Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

Uncover the truth about intermittent fasting and how it impacts women differently than men. Join us as we explore the science behind fasting, why protein-packed mornings matter, and how hormonal health plays a crucial role in determining the right approach. With expert advice and actionable tips, this clip dives deep into debunking myths and helping women optimize their health and fitness. Watch now to transform your routine!

Listen to the full episode here.

Watch the full episode on YouTube here.

***

Thank you to my wonderful sponsors! 

EXHALE COFFEE | Ridiculously healthy coffee works well for me. 

https://exhalecoffee.com/pages/sarah

Use code FREETRIALSARAH for your free trial.

Squarespace | A website makes it real. 

http://squarespace.com/LiveWell 

Get a free trial and use code LIVEWELL for 10% off your first website or domain purchase. 

***

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Better Sex EVERY TIME? Dr Rena Malik Tells You How

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***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies

https://view.flodesk.com/pages/63da7b62ecc678190062732d 

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http://bit.ly/3HDuVxj

***

Let’s be friends!

📷 Instagram:  / sarahannmacklin

📹 Subscribe:   / @livewellbewellsarah  

🐦 Twitter:  / sarahannmacklin  

📱 TikTok:  / sarahannnutrition  

💌 Newsletter: https://bit.ly/3rUbHyS

Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

Are you unknowingly consuming microplastics every day? Discover the surprising health implications of these invisible invaders and learn simple ways to protect yourself. Plus, we dive into Seasonal Affective Disorder (SAD) and how vitamin D could transform your winter blues into brighter days. Don’t miss this eye-opening clip full of practical insights and life-changing tips!

Listen to the full episode here.

Watch the full episode on YouTube here.

***

Thank you to my wonderful sponsors! 

EXHALE COFFEE | Ridiculously healthy coffee works well for me. 

https://exhalecoffee.com/pages/sarah

Use code FREETRIALSARAH for your free trial.

Squarespace | A website makes it real. 

http://squarespace.com/LiveWell 

Get a free trial and use code LIVEWELL for 10% off your first website or domain purchase. 

***

If you enjoyed this episode you might also like:

The No.1 Compassion Therapist: How To Rewire Your Brain For Courage & Kindness | Paul Gilbert

https://www.youtube.com/watch?v=uvfD8_Asj8U&t=82s

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***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies

https://view.flodesk.com/pages/63da7b62ecc678190062732d 

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http://bit.ly/3HDuVxj

***

Let’s be friends!

📷 Instagram:  / sarahannmacklin

📹 Subscribe:   / @livewellbewellsarah  

🐦 Twitter:  / sarahannmacklin  

📱 TikTok:  / sarahannnutrition  

💌 Newsletter: https://bit.ly/3rUbHyS

Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

I sat down with Paul Gilbert for one of the most eye-opening conversations about the mind. What if I told you that you didn’t actually choose your emotions? That your brain was wired long before you had any say in the matter?

We got into the shadow self, why we resist certain emotions, and how evolution basically tricked us into feeling things like shame, guilt, and fear. Paul explains why we react the way we do, why some emotions feel impossible to control, and—most importantly—how we can work with them instead of against them.

If you’ve ever felt like your mind has a mind of its own, this one’s for you.

Listen to the full episode here.

Watch the full episode on YouTube here.

***

Thank you to my wonderful sponsors! 

EXHALE COFFEE | Ridiculously healthy coffee works well for me. 

https://exhalecoffee.com/pages/sarah

Use code FREETRIALSARAH for your free trial.

Squarespace | A website makes it real. 

http://squarespace.com/LiveWell 

Get a free trial and use code LIVEWELL for 10% off your first website or domain purchase. 

***

If you enjoyed this episode you might also like:

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How to Protect Your Brain & Break Free from Ultra-Processed Foods | Dr. Chris Palmer

https://www.youtube.com/watch?v=1XwRdDU1PCY

***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies

https://view.flodesk.com/pages/63da7b62ecc678190062732d 

Unlock Stress-Busting Recipes: Get My Top 5 Mood-Boosting Meals Now! 🍽️🧘‍♀️ | Click Here to Reduce Stress Deliciously

http://bit.ly/3HDuVxj

***

Let’s be friends!

📷 Instagram:  / sarahannmacklin

📹 Subscribe:   / @livewellbewellsarah  

🐦 Twitter:  / sarahannmacklin  

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💌 Newsletter: https://bit.ly/3rUbHyS

Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

What if your mental health challenges weren’t all in your head? This clip explores the science of mitochondrial health and its surprising link to emotional well-being. Learn how to optimize your body budget, reduce stress, and build a lifestyle that truly supports your mental health. These insights could change the way you think about well-being forever. Watch now!

Listen to the full episode here.

Watch the full episode on YouTube here.

***

Thank you to my wonderful sponsors! 

EXHALE COFFEE | Ridiculously healthy coffee works well for me. 

https://exhalecoffee.com/pages/sarah

Use code FREETRIALSARAH for your free trial.

Squarespace | A website makes it real. 

http://squarespace.com/LiveWell 

Get a free trial and use code LIVEWELL for 10% off your first website or domain purchase. 

***

If you enjoyed this episode you might also like:

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***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies

https://view.flodesk.com/pages/63da7b62ecc678190062732d 

Unlock Stress-Busting Recipes: Get My Top 5 Mood-Boosting Meals Now! 🍽️🧘‍♀️ | Click Here to Reduce Stress Deliciously

http://bit.ly/3HDuVxj

***

Let’s be friends!

📷 Instagram:  / sarahannmacklin

📹 Subscribe:   / @livewellbewellsarah  

🐦 Twitter:  / sarahannmacklin  

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💌 Newsletter: https://bit.ly/3rUbHyS

Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

Can a simple walk boost your immune system by 50%? Discover the science behind nature’s incredible impact on your health, from immune-boosting forest walks to the calming effects of Blue Mind. Learn how grounding, fractals, and even looking at water can transform your well-being. Perfect for anyone looking to de-stress and reconnect with nature!

Listen to the full episode here.

Watch the full episode on YouTube here.

***

Thank you to my wonderful sponsors! 

EXHALE COFFEE | Ridiculously healthy coffee works well for me. 

https://exhalecoffee.com/pages/sarah

Use code FREETRIALSARAH for your free trial.

Squarespace | A website makes it real. 

http://squarespace.com/LiveWell 

Get a free trial and use code LIVEWELL for 10% off your first website or domain purchase. 

***

If you enjoyed this episode you might also like:

The No.1 Compassion Therapist: How To Rewire Your Brain For Courage & Kindness | Paul Gilbert

https://www.youtube.com/watch?v=uvfD8_Asj8U&t=82s

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https://www.youtube.com/watch?v=UrCxdniSLiU&t=844s

Dr. Will Bulsiewicz: Heal Your Gut Microbiome in 24 Hours

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***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies

https://view.flodesk.com/pages/63da7b62ecc678190062732d 

Unlock Stress-Busting Recipes: Get My Top 5 Mood-Boosting Meals Now! 🍽️🧘‍♀️ | Click Here to Reduce Stress Deliciously

http://bit.ly/3HDuVxj

***

Let’s be friends!

📷 Instagram:  / sarahannmacklin

📹 Subscribe:   / @livewellbewellsarah  

🐦 Twitter:  / sarahannmacklin  

📱 TikTok:  / sarahannnutrition  

💌 Newsletter: https://bit.ly/3rUbHyS

Be Well Moments brings you my favorite bite-sized highlights from the season. Enjoy quick insights from our longer conversations in a digestible format. If you'd like to listen or watch the full episode, click the link below.

Feeling empty despite achieving success? The root of this feeling might stem from long-buried experiences and unmet emotional needs. Dive into how these hidden wounds shape your life and discover the tools to finally feel whole.

Listen to the full episode here.

Watch the full episode on YouTube here.

***

Thank you to my wonderful sponsors! 

EXHALE COFFEE | Ridiculously healthy coffee works well for me. 

https://exhalecoffee.com/pages/sarah

Use code FREETRIALSARAH for your free trial.

Squarespace | A website makes it real. 

http://squarespace.com/LiveWell 

Get a free trial and use code LIVEWELL for 10% off your first website or domain purchase. 

***

If you enjoyed this episode you might also like:

The Hidden Dangers of Being TOO Productive | Oliver Burkeman

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This Is HOW You Can Architect Your Emotions | Dr. Lisa Feldman Barrett

https://youtu.be/Es2i3oLj6Nw?si=-DFwWsDtDADKByFB

***

Fuel Your Mind Weekly: Subscribe to Our Free Mental Wellness Newsletter 🧠💪 | Join Now for Expert Tips, Inspiration, and Self-Care Strategies

https://view.flodesk.com/pages/63da7b62ecc678190062732d 

Unlock Stress-Busting Recipes: Get My Top 5 Mood-Boosting Meals Now! 🍽️🧘‍♀️ | Click Here to Reduce Stress Deliciously

http://bit.ly/3HDuVxj

***

Let’s be friends!

📷 Instagram:  / sarahannmacklin

📹 Subscribe:   / @livewellbewellsarah  

🐦 Twitter:  / sarahannmacklin  

📱 TikTok:  / sarahannnutrition  

💌 Newsletter: https://bit.ly/3rUbHyS