AGEIST

Dr. Jeffrey Bland, 80, draws a sharp line between being elderly and being an elder: one has lost function and become dependent, the other stays wise, capable, and still contributing to the people around them. In this conversation, Dr. Bland explains why he's built his current company, Big Bold Health, around the immune system, since it's the one system embedded in every tissue in the body and central to how we age at the cellular level. The researcher credited with coining the term functional medicine back in 1990 shares results from an 800-person clinical trial on Himalayan Tartary Buckwheat. An ancient Chinese grain his team stumbled into almost by accident, this superfood improved cognitive performance by 27 percent in just 90 days by reprogramming the epigenetic markers on immune cells. Listeners will come away with a clearer picture of how diet, environment, and daily habits can switch specific genes on or off, and why the goal of longevity isn't just more years, but more years spent as the version of yourself still capable of contributing.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

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Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"Nature will give over her secrets."

"Elders are individuals that are wise, that are still functional, still making contributions, still being part of the productive society."

"We make over one million new immune cells every second."

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Big Bold Health 

The Disease Delusion

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Paul Coletta isn’t a doctor or a scientist, which he says is exactly why he can explain proteomics in three sentences, not a confusing research paper. In this conversation, the founder of Vero Bioscience walks through what a single vial of blood can reveal about the biological age of eleven different organs. He discusses technology built in Stanford neuroscientist Tony Wyss-Coray’s lab and just spotlighted in TIME’s 2026 Longevity Leaders issue and why his own test came back showing a kidney seven years older than the rest of him–a signal his traditional labs had missed entirely. He makes the case that a single biological age number is the wrong place to stop, since averaging your organs together hides exactly the risk you’d want to catch early. Listeners will hear how Coletta has spent two years running his own N-of-1 experiment in response, adjusting his sleep, light exposure, and supplements, and what it actually takes to turn a prediction into a measurable, reversible result.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

BEAM Minerals: Plant-based liquid minerals for replenishing the foundational compounds your body needs to age well. Listeners can now get 20% off their first BEAM purchase by using the code “AGEIST” at checkout at BeamMinerals.com/ageist.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Key Moments

“You are only as healthy as your oldest organ.”

“It’s not what’s happened to you, it’s what might happen to you if you don’t intervene.”

“Aim for the stars, hit the moon.”

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Nearly two decades after co-founding Fitbit and putting personal health tracking on people's wrists, James Park has turned his attention to a harder problem: the invisible mental load carried by roughly one in four American adults now caring for an aging family member. In this conversation, he explains how Luffu, his new AI-powered platform, turns scattered observations, a doctor's note, a missed pill, a change in sleep, into a shared model a family can actually act on, without requiring the aging parent to hand over their privacy in the process. 

He talks candidly about the tension at the center of caregiving technology: the caregiver wants to know everything out of anxiety, while the person receiving care simply wants the dignity of an autonomous life, and he explains how Luffu is designed to please both sides. Listeners will come away with a clearer sense of what caregiving actually costs beyond the hours logged, and what it might look like to finally put some of that mental weight into a system instead of carrying it alone.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

BEAM Minerals: Plant-based liquid minerals for replenishing the foundational compounds your body needs to age well. Listeners can now get 20% off their first BEAM purchase by using the code “AGEIST” at checkout at BeamMinerals.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"Your desire for reassurance doesn't automatically justify unlimited access to everything."

"There's this component of caregiving that's not just the physical work or the act of doing something."

"This is a very worthy, meaningful problem that I think affects so many people, but in some weird way is like hidden, hidden away as well."

"You always wanna start with thinking about the autonomy of the person receiving the care versus starting with the anxiety of the caregiver."

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We're revisiting a fan favorite this week: our September 2024 conversation with Dr. Stacy Sims, the exercise physiologist behind one of the most useful ideas in women's fitness: women are not small men, and their training shouldn't be built as if they were. We're getting excited because Dr. Sims is preparing to join us at the Super Age Games this November, and can’t wait to celebrate women in sports, science, and longevity alongside her. In this episode, Dr. Sims breaks down why women over 40 need to emphasize heavy lifting and high-intensity intervals, and why perimenopause is the pivot point that changes almost everything about how a woman's body responds to exercise.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"Women don't age in a linear fashion like men do. Hormonal changes hit much earlier and more dramatically."

"For women over 40, lifting heavy isn't optional—it's essential for maintaining lean mass and bone density."

"Women are already metabolically flexible. High-intensity is where the real gains are."

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Stacy’s book: Roar

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After twenty five years as a traditional orthopedic surgeon, Dr. Elizabeth Yurth walked away from a specialty she says patches the body instead of heals it. This was a shift that eventually led her to found the Boulder Longevity Institute. In this conversation, she explains why a common knee surgery called arthroscopic debridement has been abandoned in most countries, and why cheap, decades-old lab values like creatinine and ALT are routinely misread by doctors who are misinformed on these measures. She also makes the case for treating peptides the same way we treat hormones: as naturally occurring compounds the body simply stops producing with age, not a bodybuilding shortcut or a biohacking fad. Dr. Yurth leaves listeners with a clearer, more skeptical eye for what is being marketed to them, and a working definition of healthy aging that shifts the focus from simply a lab report.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

BEAM Minerals: Plant-based liquid minerals for replenishing the foundational compounds your body needs to age well. Listeners can now get 20% off their first BEAM purchase by using the code "AGEIST" at checkout at BeamMinerals.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"If all we're doing is patching people back up for them to fall apart again, what are we doing wrong?"

"They actually found that 80% of people worsened after this surgery, not just didn't get better."

"I don't need an $800 immune test to tell me. I can look at your neutrophil [to] lymphocyte ratio."

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Boulder Longevity Institute

Human Optimization Academy

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We're bringing back our May 2025 conversation with Denise Kirtley, the founder of Rebellion Body. As we look back on this message, Kirtley is preparing to head to the Super Age Games with the event's largest team yet, more than 50 women strong. Kirtley built her coaching business on the idea that midlife is not a decline to manage, but a version of life women get to design on purpose. In this conversation, she explains why belief, not willpower, is usually the first thing that has to change before a body does. She also gets into the backlash she receives for posting bikini photos in her fifties, her wariness about AI-generated bodies flooding social media, and why she thinks the phrase "50 is the new 30" gets the whole conversation backward. Listeners will come away with an answer to the question that stalls most people before they ever begin: what do you do on the days you don't feel motivated at all?

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more and read more about Team Rebellion Body's prep for the Games: How the Super Age Games' Biggest Team Is Preparing

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"I always like to say my new thing is 50 is the new 50."

"I think people think motivation is like this mythical thing that all of a sudden the clouds open and you get the sign from the heavens that ‘Now is the time.’ It doesn't work that way. You just do it."

"We cannot worry about the things that naturally happen as we age."

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Rebellion Body
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Before Andrew Salisbury became captivated by the biochemistry of coffee, he set a Guinness World Record jumping out of a helicopter tethered to a bungee cord over Cancun, part of a career that has swung between call center software, extreme sports, and now one of the country's fastest-growing coffee companies. In this conversation, the founder of Purity Coffee explains why much of the coffee on the market fails basic testing for mold and heavy metals, and walks through how various factors change how much of coffee's antioxidant benefit actually reaches your cup. He makes the case that coffee's health benefits come from its polyphenols and chlorogenic acids rather than its caffeine, a distinction he says the industry gets backward. Listeners will also hear about his newest venture, a honey partnership with an indigenous community in the Amazon, and why he thinks the choice of what you drink every single day matters more than most supplements.

Bonus: Save 20% on your order at puritycoffee.com with code AGEIST

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

• "It's not the caffeine in the coffee that gives you the health benefits."
• "You need to lab test [coffee] to make sure that it's free of mycotoxins."
• "I went from the million dollar sort of systems that we were selling that would take a year, year and a half, to selling 25 dollar bags of coffee."

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Purity Coffee

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Kim Alexis, 80s supermodel turned integrative health practitioner and host of the podcast Unexpired, talks about the mindset shift that let her build a real estate career, a fitness certification, and a health practice, all after turning 64. She explains why she has chosen against surgery, how she manages her arthritis, and why she makes conscious health decisions in her weekly routine. Alexis also opens up about her instinct to over-explain herself to fans who criticize her changing appearance, and the wisdom that has slowly replaced that people-pleasing habit with peace. She closes with what keeps her looking forward at 66: a new grandson, a growing podcast, and a daily practice of gratitude.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"When people see me and they see that I've aged, it reminds them, because they grew up with me, that they have aged also."

"No fillers, no shots, no plaque injected in my face. I just don't want it."

"I would say go at life with a grateful, joyful heart and be looking around the corner."

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Unexpired 

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Super Health: Kim's Stories of Getting Her Health Back

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We're revisiting a favorite conversation this week: our September 2023 sit-down with Dr. Kelly Stankiewicz, one of our go-to dermatologists. Dr. Kelly specializes in laser skin treatments that combat the effects of aging and can even create a youthful glow, if that's your jam. We also break down the four core pillars of a sound skincare routine: cleanse, exfoliate, nourish, and protect. And I asked Dr. Kelly for context around Jimmy Buffett's death and the skin cancer he battled, along with what we can all do to protect ourselves.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

True Nutrition: Stop settling for what's on the shelf and build the protein blend that fits your lifestyle at truenutrition.com/AGEIST and use code AGEIST for 20% off your first custom blend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

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 Key Moments:

“What's important is that you're hitting all four of the categories: sunscreens, antioxidants, exfoliants, and cleansers.”

“So people, when they hear that someone has died of skin cancer, they get very concerned because skin cancer is quite common. The type that Jimmy Buffett had is very, very rare. So all of my patients who've had multiple basal cell carcinomas and squamous cell carcinomas, which don't typically metastasize, are, you know, kind of up in arms because they don't really understand the difference.”

“When you're doing fractional resurfacing, you're decreasing your risk for skin cancer probably (or at least according to this one study) by about two times or maybe a little bit more.” 

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Amy Odell, the journalist behind the biographies Anna, and the newly released Gwyneth, joins the show to trace how a $6.8 trillion wellness industry has learned to monetize our fear of aging. She explains why Gwyneth Paltrow's most outrageous claims may not be cynical marketing at all, connecting research on conspiracy belief and narcissistic traits to how someone builds and defends a brand.

Later, The conversation turns to plastic surgery's shift from private secret to public status symbol. A facelift can change a face without changing how old people perceive it. Odell and host David Stewart also dig into the harder distinction beneath all of it: aging as a matter of physical capacity versus a matter of appearance, and why culture keeps confusing the two.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

True Nutrition: Stop settling for what's on the shelf and build the protein blend that fits your lifestyle at truenutrition.com/AGEIST and use code AGEIST for 20% off your first custom blend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"The wellness industry is valued, according to the Global Wellness Institute, I believe at $6.8 trillion globally... It's bigger than big ag. It's bigger than big pharma."

"I do think that [Gwyneth] believes the things that she promotes, even if they seem crazy to us... there's some research that people who believe conspiracy theories have traits of narcissism."

"I think we live in an ageist society... there's so much money made in selling people this idea of eternal youth."

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Newsletter (Back Row)

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Gwyneth: The Biography

Anna: The Biography

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