We're revisiting a fan favorite this week: our September 2024 conversation with Dr. Stacy Sims, the exercise physiologist behind one of the most useful ideas in women's fitness: women are not small men, and their training shouldn't be built as if they were. We're getting excited because Dr. Sims is preparing to join us at the Super Age Games this November, and can’t wait to celebrate women in sports, science, and longevity alongside her. In this episode, Dr. Sims breaks down why women over 40 need to emphasize heavy lifting and high-intensity intervals, and why perimenopause is the pivot point that changes almost everything about how a woman's body responds to exercise.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

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Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"Women don't age in a linear fashion like men do. Hormonal changes hit much earlier and more dramatically."

"For women over 40, lifting heavy isn't optional—it's essential for maintaining lean mass and bone density."

"Women are already metabolically flexible. High-intensity is where the real gains are."

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Stacy’s book: Roar

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After twenty five years as a traditional orthopedic surgeon, Dr. Elizabeth Yurth walked away from a specialty she says patches the body instead of heals it. This was a shift that eventually led her to found the Boulder Longevity Institute. In this conversation, she explains why a common knee surgery called arthroscopic debridement has been abandoned in most countries, and why cheap, decades-old lab values like creatinine and ALT are routinely misread by doctors who are misinformed on these measures. She also makes the case for treating peptides the same way we treat hormones: as naturally occurring compounds the body simply stops producing with age, not a bodybuilding shortcut or a biohacking fad. Dr. Yurth leaves listeners with a clearer, more skeptical eye for what is being marketed to them, and a working definition of healthy aging that shifts the focus from simply a lab report.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

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LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"If all we're doing is patching people back up for them to fall apart again, what are we doing wrong?"

"They actually found that 80% of people worsened after this surgery, not just didn't get better."

"I don't need an $800 immune test to tell me. I can look at your neutrophil [to] lymphocyte ratio."

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Boulder Longevity Institute

Human Optimization Academy

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We're bringing back our May 2025 conversation with Denise Kirtley, the founder of Rebellion Body. As we look back on this message, Kirtley is preparing to head to the Super Age Games with the event's largest team yet, more than 50 women strong. Kirtley built her coaching business on the idea that midlife is not a decline to manage, but a version of life women get to design on purpose. In this conversation, she explains why belief, not willpower, is usually the first thing that has to change before a body does. She also gets into the backlash she receives for posting bikini photos in her fifties, her wariness about AI-generated bodies flooding social media, and why she thinks the phrase "50 is the new 30" gets the whole conversation backward. Listeners will come away with an answer to the question that stalls most people before they ever begin: what do you do on the days you don't feel motivated at all?

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more and read more about Team Rebellion Body's prep for the Games: How the Super Age Games' Biggest Team Is Preparing

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Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"I always like to say my new thing is 50 is the new 50."

"I think people think motivation is like this mythical thing that all of a sudden the clouds open and you get the sign from the heavens that ‘Now is the time.’ It doesn't work that way. You just do it."

"We cannot worry about the things that naturally happen as we age."

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Rebellion Body
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Before Andrew Salisbury became captivated by the biochemistry of coffee, he set a Guinness World Record jumping out of a helicopter tethered to a bungee cord over Cancun, part of a career that has swung between call center software, extreme sports, and now one of the country's fastest-growing coffee companies. In this conversation, the founder of Purity Coffee explains why much of the coffee on the market fails basic testing for mold and heavy metals, and walks through how various factors change how much of coffee's antioxidant benefit actually reaches your cup. He makes the case that coffee's health benefits come from its polyphenols and chlorogenic acids rather than its caffeine, a distinction he says the industry gets backward. Listeners will also hear about his newest venture, a honey partnership with an indigenous community in the Amazon, and why he thinks the choice of what you drink every single day matters more than most supplements.

Bonus: Save 20% on your order at puritycoffee.com with code AGEIST

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

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Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

• "It's not the caffeine in the coffee that gives you the health benefits."
• "You need to lab test [coffee] to make sure that it's free of mycotoxins."
• "I went from the million dollar sort of systems that we were selling that would take a year, year and a half, to selling 25 dollar bags of coffee."

Connect with Andrew Salisbury

Purity Coffee

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Kim Alexis, 80s supermodel turned integrative health practitioner and host of the podcast Unexpired, talks about the mindset shift that let her build a real estate career, a fitness certification, and a health practice, all after turning 64. She explains why she has chosen against surgery, how she manages her arthritis, and why she makes conscious health decisions in her weekly routine. Alexis also opens up about her instinct to over-explain herself to fans who criticize her changing appearance, and the wisdom that has slowly replaced that people-pleasing habit with peace. She closes with what keeps her looking forward at 66: a new grandson, a growing podcast, and a daily practice of gratitude.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"When people see me and they see that I've aged, it reminds them, because they grew up with me, that they have aged also."

"No fillers, no shots, no plaque injected in my face. I just don't want it."

"I would say go at life with a grateful, joyful heart and be looking around the corner."

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Website 

Unexpired 

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Facebook

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Super Health: Kim's Stories of Getting Her Health Back

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We're revisiting a favorite conversation this week: our September 2023 sit-down with Dr. Kelly Stankiewicz, one of our go-to dermatologists. Dr. Kelly specializes in laser skin treatments that combat the effects of aging and can even create a youthful glow, if that's your jam. We also break down the four core pillars of a sound skincare routine: cleanse, exfoliate, nourish, and protect. And I asked Dr. Kelly for context around Jimmy Buffett's death and the skin cancer he battled, along with what we can all do to protect ourselves.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

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True Nutrition: Stop settling for what's on the shelf and build the protein blend that fits your lifestyle at truenutrition.com/AGEIST and use code AGEIST for 20% off your first custom blend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Get in touch with Dr. Kelly
Website
Contact

 Key Moments:

“What's important is that you're hitting all four of the categories: sunscreens, antioxidants, exfoliants, and cleansers.”

“So people, when they hear that someone has died of skin cancer, they get very concerned because skin cancer is quite common. The type that Jimmy Buffett had is very, very rare. So all of my patients who've had multiple basal cell carcinomas and squamous cell carcinomas, which don't typically metastasize, are, you know, kind of up in arms because they don't really understand the difference.”

“When you're doing fractional resurfacing, you're decreasing your risk for skin cancer probably (or at least according to this one study) by about two times or maybe a little bit more.” 

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Amy Odell, the journalist behind the biographies Anna, and the newly released Gwyneth, joins the show to trace how a $6.8 trillion wellness industry has learned to monetize our fear of aging. She explains why Gwyneth Paltrow's most outrageous claims may not be cynical marketing at all, connecting research on conspiracy belief and narcissistic traits to how someone builds and defends a brand.

Later, The conversation turns to plastic surgery's shift from private secret to public status symbol. A facelift can change a face without changing how old people perceive it. Odell and host David Stewart also dig into the harder distinction beneath all of it: aging as a matter of physical capacity versus a matter of appearance, and why culture keeps confusing the two.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

True Nutrition: Stop settling for what's on the shelf and build the protein blend that fits your lifestyle at truenutrition.com/AGEIST and use code AGEIST for 20% off your first custom blend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

"The wellness industry is valued, according to the Global Wellness Institute, I believe at $6.8 trillion globally... It's bigger than big ag. It's bigger than big pharma."

"I do think that [Gwyneth] believes the things that she promotes, even if they seem crazy to us... there's some research that people who believe conspiracy theories have traits of narcissism."

"I think we live in an ageist society... there's so much money made in selling people this idea of eternal youth."

Connect with Amy Odell

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Newsletter (Back Row)

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Gwyneth: The Biography

Anna: The Biography

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Longer life is changing what people over 50 expect from medicine, themselves, and the decades ahead. In this encore episode, Dr. Michael Roizen argues that aging is increasingly shaped by informed choices, while the current culture surrounding longevity struggles to separate useful evidence from expensive fads.

Roizen examines the science behind epigenetic switches, protein cycling, metformin, stem cells, cardiovascular risk, and balance. The conversation offers a practical framework for evaluating new claims, protecting physical and cognitive function, and asking better questions before adopting a new treatment or supplement.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

True Nutrition: Stop settling for what’s on the shelf and build the protein blend that fits your lifestyle at truenutrition.com/AGEIST and use code AGEIST for 20% off your first custom blend.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Key Moments

“You’re a better genetic engineer for you than anyone else who went to Caltech or MIT.”

"Stressing the muscle not only repairs the muscle, but it turns on a gene that produces a small protein, which gets to the brain and makes the brain bigger. That’s why physical activity, we think, is so good for memory."

"Can we make a hundred year old person a 40 year old person? In other words, can we extend the period of life between when you’re most productive, your 40s to 60s, to being between 40 and 90? And that’s where a lot of the aging mechanism research is going."

Connect With Dr. Roizen

Cleveland Clinic 

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Book: The Great Age Reboot

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Longevity has become a status symbol, marketing term, and in some spaces, a kind of show. Jill Brand joins The AGEIST Podcast to talk about what gets lost when better living becomes another performance, and why movement remains one of the interventions that actually changes daily life.

As Head of Branding, Content, and Creative at Pvolve, Brand challenges us to think on muscle, mobility and stability, GLP-1s, injury prevention, and the psychology of trusting your body. The episode gives listeners a clearer way to think about fitness after 40. Rather than as punishment or spectacle, Jill urges us to consider it to be the work that keeps people independent, capable, and connected to the lives they still want to have.

Special Thanks to Our Sponsors

True Nutrition: Stop settling for what's on the shelf and build the protein blend that fits your lifestyle at truenutrition.com/AGEIST and use code AGEIST for 20% off your first custom blend.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

Key Moments

“Movement is life. Move your body.”

“Muscle is kind of like the secret to long life, to better living.”

“Whatever gets you moving is the right workout for you right now.”

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Pvolve

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Episode 293 asks: what happens when beauty culture moves from correction toward regeneration, and why should we be more demanding about the evidence behind products that promise younger-looking skin?  Alisa Lask, CEO of Rion Aesthetics and ( plated )™ Skin Science, explains exosomes as the body’s cellular messaging system, with platelet-derived signals that may support renewal, barrier function, and post-procedure recovery.

The conversation separates credible regenerative aesthetics from marketing noise, with practical guidance on PRP, lasers, sunscreen, skinspan, and what to ask before trusting any new skincare claim. Lask also discusses hair health, menopause-related thinning, and the larger possibility that exosomes may reshape how medicine thinks about repair.

Join Us at the 2026 Super Age Games! Visit games.superage.com to learn more.

Special Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.

LMNT Electrolytes: Try the all-new Lemonade Iced Tea! Our #1 electrolyte mix for optimal hydration. Get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.

Key Moments

“We're moving from hurt, so it heals to tell [your skin] to renew.”

“You want proof, not promise.”

“Consistency is the most important thing.”

Connect with Alisa Lask

Rion Aesthetics

( plated )™ Skin Science

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Tune in to hear more on this episode of The AGEIST Podcast or check out the full interview transcript.

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