In this week’s episode, Jennifer Vaughan Maanavi, founder of Physique 57, shares why fitness must be the foundation of any wellness plan—especially as we age. She explains how the explosion of wellness trends has dangerously shifted focus away from physical health. Jennifer offers powerful insights on building a sustainable, results-driven fitness habit that supports brain health, cardiovascular health, and emotional well-being. Listeners will come away with a clear, actionable framework for prioritizing fitness as a true cornerstone of longevity and life quality.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

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LMNT Electrolytes — our number one electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. 

Chapters

(10:15) Jennifer's Journey from Finance to Fitness

(20:28) The Evolution of the Wellness Industry

(27:27) Integrating Fitness into the Healthcare Continuum

(30:21) The Importance of Fitness in Wellness

(34:50) Fitness as a Foundation for Wellness

(36:50) The Evolving Landscape of Wellness Activities

(41:04) The Need for Outcome-Driven Fitness Conversations

(42:38) The Role of Nutrition and Supplements in Wellness

(44:41) The Future of Fitness in Medical Prescriptions

Key Moments

"Wellness is taking over and it's not bringing fitness with it."

"You have to think about now—present value—who you are now and how you’re going to bring yourself into the future."

"Fitness is preventative care; it’s the key to preventative care."

Connect with Our Guest
Website: https://physique57.com
Instagram: https://instagram.com/physique57
LinkedIn: https://www.linkedin.com/in/jennifervaughanmaanavi/

Book: The Physique 57 Solution

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Physical therapist and endurance athlete Dr. Mike Studer joins us this week to break the myth of a one-size-fits-all approach to health. He shares why personalization—based on genetics, performance metrics, and lifestyle—is critical to long-term success in fitness, nutrition, and mental wellbeing. From sleep consistency to gut microbiome insights, Dr. Studer lays out practical strategies to help listeners become their own best scientist. Tune in to learn how to effectively experiment, track outcomes, and stop feeling like a failure for not thriving on someone else's plan.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

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Fatty15 – C15 is the first essential fatty acid to be discovered In 90 years. Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter code: AGEIST at checkout.

Meditate Happier – Navigating menopause isn’t just about managing physical symptoms—it’s about supporting your mind and emotions too. That’s why Meditate Happier created the Mindful Menopause Guide, with Diana Winston. It is a free, expert-led course designed to help you move through menopause with more ease, confidence, and calm. Click this link or visit: www.meditatehappier.com/menopause

Troscriptions — Precise, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code: AGEIST for 10% off, or click here.

Chapters

(03:25) Understanding SNPs and Personal Choices

(09:19) The Role of Autonomy and Beliefs in Health

(15:54) Gamification and Measurement in Health Choices

(17:46) The Importance of Sleep and Its Variability

(22:50) Genetics, Microbiome, and Personal Health

(26:08) Becoming Your Own Scientist in Health

(28:01) The Personalization of Health and Wellness

(32:36) Conclusion: Statistics vs. Individual Experience

Key Moments

“Statistics are for populations, not people.”

“We’re always our own best scientist and best prescriber.”

“You get dopamine, serotonin, and oxytocin from doing what you believe is healthy for your future self.”

Connect with Our Guest

• Website: MikeStuder.com
  
  
• LinkedIn: Mike Studer on LinkedIn
  
  
• Book: The Brain That Chooses Itself

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Matt Zemon, author and psychedelic therapy advocate, joins us to explain how non-ordinary states of consciousness can help rewire repetitive thought patterns. He breaks down how psychedelics are being used not just for trauma recovery but to foster growth and deeper self-understanding. This episode also covers the rise of industrialized addiction and the tools available to counter its effects—from ketamine to breathwork to community. Whether you're struggling or thriving, Zemon offers grounded, practical ways to live with more intention and connection.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

Join our Ask David Anything Webinar on April 24th, 8pm EST. 

Special Thanks to Our Sponsors

Our Place – Our top cookware brand for non-toxic, PFA-free pots and brands. Use code “AGEIST” for 10% off at fromourplace.com 

LMNT Electrolytes: Our number-one electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. 

fatty15: C15:0 is the first essential fatty acid to be discovered in 90 years, and fatty15 is on a mission to replenish your C15:0 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter the code “AGEIST” at checkout.

Key Quotes
“These medicines remind us that there are other ways to think about ourselves, our relationships, our jobs, our lives.”

“I already am everything, as are you. And I don’t need to become, I need to be.”

“You're not broken. You just forgot how powerful you were.”

Chapters
(03:15) The Intersection of Psychedelics and Addiction
(06:28) Psychedelics and Mental Health
(09:28) Cultural Context of Addiction
(12:21) Personal Experiences with Psychedelics
(15:02) The Role of Connection and Community
(18:07) Revelations and Non-Ordinary States of Consciousness
(24:13) The Beauty of Life and Death
(28:02) Transformative Journeys: Veterans and Psychedelics
(30:00) Healing Through Psychedelics: A New Hope
(33:23) Mindset Matters: Abundance vs. Scarcity
(34:56) Exploring Psychedelics: Legal and Safe Access
(37:24) Understanding Risks in Psychedelic Use
(40:59) Navigating Change: Being Human in the 21st Century
(42:07) Tools for Living: Expanding the Toolbox

Connect with Matt Zemon

Website

Instagram (@matt.zemon)

Books: Psychedelics for Everyone andA Veteran’s Guide to Psychedelics 

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Craig Cooper, former professional athlete and author of Your New Prime, shares the overlooked realities men face as they age. He opens up about reversing his own osteoporosis and why many men fail to prioritize bone health. Craig breaks down why typical fitness routines may actually accelerate aging and offers science-backed alternatives for maintaining strength, metabolic function, and cardiovascular resilience. This episode equips listeners with practical, often ignored insights into how to stay strong, capable, and engaged well beyond midlife.

This May 26-31 in Santa Fe, NM, Rebecca Rusch and AGEIST founder David Stewart are hosting what might be the most transformative week of your year. It's what Rebecca calls "adult play summer camp," blending cutting-edge science with genuine joy.

Ideal for all fitness levels – whether you're a seasoned athlete or just getting started on your wellness journey.

Ready to feel better than you have in years? Your future self is waiting at meawisdom.com/enroll

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Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with the code “AGEIST” at TimelineNutrition.com/ageist.

Our Place: Our top cookware brand for non-toxic, PFA-free pots and pans. Use code “AGEIST” for 10% off at fromourplace.com.

Chapters

(00:15) Introduction to Craig Cooper and His Journey
(06:42) The Evolution of Health Perspectives in Aging
(13:04) Bone Health: Overcoming Osteopenia
(17:29) Cardiovascular Health and Longevity
(24:48) Nutrition and Dietary Choices for Better Aging
(26:57) Understanding Cardiovascular Health Tests
(33:04) The Importance of Early Detection in Health
(36:12) Cardiovascular Disease: The Leading Cause of Death
(40:52) Practical Health Monitoring Tips
(42:54) The Role of Personal Responsibility in Health
(46:20) Inspiring Stories of Resilience and Health
(52:12) Nutritional Strategies for Bone Health

Key Moments
“Hormonally, [training] long slow distance just really just sucks your manhood.”

“You really can’t have a discussion around longevity without focusing on arterial health.”

“I've had doctors come out of UCLA to look at what I've been doing… they've never seen this sort of switch that I've been able to execute on my bone health over the course of five years.”

Connect With Craig Cooper
Conneqt Health: conneqthealth.com

LinkedIn: https://www.linkedin.com/in/craigcooper007/

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Dr. Paul Kolodzik spent 25 years in emergency medicine watching the long-term consequences of preventable disease. Now, he’s helping patients reverse metabolic syndrome using continuous glucose monitors (CGMs), low-carb nutrition, and strength training. In this episode, Dr. Kolodzik explains why blood sugar spikes—not cholesterol—may be the most urgent threat to long-term health. You’ll also hear why he believes wearables and strategic use of GLP-1 medications can radically change your health trajectory.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

Thanks to Our Sponsors
Troscriptions — Precision, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code: AGEIST for 10% off, or click here.

LMNT Electrolytes — Our number one electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. 

Our Place – Our top cookware brand for non-toxic, PFA-free pots and pans. Use code “AGEIST” for 10% off at fromourplace.com 

Chapters

(00:15) Introduction to Metabolic Health and CGMs

(03:28) Understanding Fatty Liver Disease and Carbohydrate Impact

(06:10) The Role of Continuous Glucose Monitors (CGMs)

(09:06) Insulin Resistance and Metabolic Syndrome

(12:04) The Relationship Between Blood Sugar and Weight Gain

(15:18) Dietary Approaches to Managing Blood Sugar

(18:08) The Importance of Personalization in Diet

(21:11) Inflammation, Brain Health, and Blood Sugar

(24:14) Understanding A1C and Blood Sugar Metrics

(29:13) Understanding Blood Sugar Levels

(35:15) The Role of Exercise in Insulin Resistance

(41:08) Integrating GLP-1 Medications with CGMs

(47:25) The Importance of Continuous Glucose Monitoring

(51:07) Empowerment Through Data and Personal Health Management

Key Moments
Fatty liver disease isn’t from eating too much fat — it’s, for most people, excessive carb intake.

Once I see it, I can’t unsee it. And then you know what’s going on with your blood sugar physiology.

Strength training reverses insulin resistance. Your muscles are soaking up more insulin and more blood glucose

Connect with Dr. Paul Kolodzik
CGM Doctor — https://cgm-doctor.com

MetabolicMDs Practice — https://metabolicmds.com

Book:
The Continuous Glucose Monitor Revolution for Non-Diabetics — https://www.amazon.com/dp/B0BHL5YZXV

Social Media:
 LinkedIn — linkedin.com/in/paulkolodzik/

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At 32, Todd Vande Hei was told his declining health was just “part of getting older,” and he believed it—until he didn’t. Along with sharing how a shift in perspective led him to pursue measurable strategies to improve his well-being, he talks about ways you, too, can become the CEO of your own health. If you're tired of vague advice and want a smarter, test-based approach to longevity, this conversation will show you how to start.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

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BON CHARGE: Want to try the hottest sauna blanket on the market? Check out BON CHARGE’s Infrared Sauna Blanket, which is designed to provide easy access to the benefits of infrared heat therapy in the comfort of your own home, here.

Troscriptions — Precision, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code: AGEIST for 10% off, or click here.

Fatty15 – C15 is the first essential fatty acid to be discovered In 90 years. Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter code: AGEIST at checkout.

Chapters

(00:15) Introduction to Todd van de Heide and Stark Health

(03:21) Todd's Health Journey: From Struggles to Transformation

(06:14) The Importance of a Health Team

(09:13) Questioning Medical Authority and Seeking Alternatives

(12:14) The Role of Measurement in Health Optimization

(15:04) The Evolution of Health Perspectives

(18:28) Agency and Responsibility in Personal Health

(21:21) The Future of Health and Medical Research

(32:18) The Importance of Humility in Medicine

(36:14) Defining Normal Health vs. Optimal Health

(44:00) Shifting from Limitation to Possibility Mindset

(49:51) Strategies for Health Across the Decades

(55:42) Integrating Health, Work, and Life

(59:38) Time Management for Well-Being

Key Moments

“You have to be the CEO of your own health.”

“Half of what doctors believe today will be proven wrong in 18 months—so you have to ask, what if they’re wrong?”

“Your health is more important than your money, yet most people track their finances far more carefully.”

Connect With Todd Vande Hei
Stark Health

Instagram: @testodderone 

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Are you eating the right way for your goals? Performance nutritionist Dr. Marc Bubbs has spent 20 years working with Olympic athletes, elite sports teams, and executives to optimize their health through diet and lifestyle. In this episode, he explains how nutrition isn’t one-size-fits-all, why carbs aren’t the enemy, and how small changes in your daily habits can have massive long-term impacts. Whether you’re a competitive athlete or just want to feel better, Dr. Marc breaks down the science behind what actually works—without the fads and misinformation that flood social media.

Interested in trying ProBio Nutrition? Click here, to apply discount code AGEIST20 at checkout and save 20% on your order.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

Chapters

(04:12) Understanding Performance Nutrition
(10:09) Fueling Different Types of Athletes
(16:20) Nutrition for the General Population
(22:11) Protein Intake and Its Importance
(28:17) Building a Nutritional Foundation
(32:46) Reframing Food Mindset for Weight Management
(35:09) Understanding Carbohydrates and Blood Sugar Control
(39:09) The Evolving Perspective on Fats
(47:11) The Role of Collagen and Vitamin C in Nutrition
(50:04) Performance Nutrition: A Holistic Approach

Thanks to Our Sponsors
Troscriptions — Precision, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code: AGEIST for 10% off, or click here.

Timeline Nutrition — Our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist.

LMNT Electrolytes — Our number one electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. 

Key Moments
“We want you to enjoy life and food—if we do well Monday to Friday, you can live a little on the weekends.”

“If you wake up exhausted, lean on caffeine, and make bad food choices all day, the problem isn’t willpower—it’s how you set up your mornings and nights.”

“Most people think performance nutrition is just for Olympians, but the same principles apply whether you're training for gold or just trying to keep up with your kids.”

Connect With Dr. Marc Bubbs
Website: drbubbs.com

Instagram: instagram.com/drbubbs

X: twitter.com/DrBubbs

Books: Peak and Peak 40  

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What if you could increase your energy, improve your focus, and optimize your brain health with just one simple lozenge? Dr. Scott Sherr, an expert in health optimization, joins us on the show once more to discuss methylene blue, a powerful mitochondrial enhancer that has been used for over a century. He explains how this compound boosts cognition, helps fight infections, and even improves endurance for athletes. If you’ve been feeling sluggish, struggling with brain fog, or looking for a smarter approach to supplements, this episode is packed with science-backed insights you can start using today.

How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz

Troscriptions — Precision, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code: AGEIST for 10% off, or click here.

Thanks to Our Sponsors

Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with the code “AGEIST” at TimelineNutrition.com/ageist.

BON CHARGE: Harness the power of both infrared and red light therapy in the comfort of your own home with the Red Light Face Mask from BON CHARGE. To try their professional-grade technology for yourself, use the code “AGEIST15” for 15% off sitewide.

fatty15: C15:0 is the first essential fatty acid to be discovered in 90 years. fatty15 is on a mission to replenish your C15:0 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter the code “AGEIST” at checkout.

Chapters

(00:00) Introduction to Methylene Blue
(02:24) Methylene Blue's Health Benefits
(08:03) The History and Mechanism of Methylene Blue
(13:00) Cognitive Effects and Mitochondrial Function
(18:20) Dosage and Timing for Methylene Blue
(24:17) Practical Applications and Endurance Benefits(
(35:19) Mitochondrial Health and Aging
(37:39) Methylene Blue: A Path to Health Optimization
(45:22) Utilizing Methylene Blue for Performance
(52:05) Methylene Blue and Red Light Therapy Synergy
(58:03) Practical Applications and Future of Methylene Blue

Key Moments
“Methylene blue works like oxygen in your cells, helping your body produce energy even in low-oxygen environments.”

“If you don’t have working mitochondria in your brain, you won’t have optimal cognitive function.”

“Stress, poor sleep, and toxins in our environment are killing our mitochondria—this is why so many people feel tired all the time.”

Connect With Dr. Scott Sherr & Troscriptions

Website

Instagram (@drscottsherr)

Troscriptions

Methylene Blue

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What if you could improve your memory, decision-making, and focus just by making small tweaks to your daily routine? Cognitive psychologist and author Therese Huston, PhD, joins us to share practical, science-backed strategies for boosting brain health at any age. She explains why stress kills creativity, how dancing can actually grow new brain cells, and why older adults often make better big-picture decisions than younger ones. Whether you want to sharpen your focus or protect your memory, this episode offers actionable advice to help you think and perform at your best.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

Thanks to Our Sponsors
LMNT Electrolytes — our number one electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. 

Troscriptions — Precision, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code AGEIST for 10% off.

Fatty15 – C15 is the first essential fatty acid to be discovered In 90 years. Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter code: AGEIST at checkout.

Chapters

(00:00)
Introduction to Therese Huston, Ph.D

(05:54)
Strategies for Enhancing Creativity

(11:09)
The Role of Emotions in Decision Making

(17:56)
Memory Challenges and Solutions

(28:24)
Creating Connections for Memory

(29:58)
Understanding Brain Changes with Age

(32:09)
The Benefits of Dance for Brain Health

(36:02)
Cognitive Advantages of Aging

(43:08)
Harnessing Binaural Beats for Focus

(51:09)
Practical Tips for Brain Health

Key Moments
“One of the best ways to get creative is to bring your stress levels down.”

“Your brain at 50 or 60 is actually better at big-picture thinking because the two hemispheres are working together more efficiently.”

“Taking a dance class for six months can literally grow new neurons in your hippocampus, which helps memory.”

Connect With Dr. Huston
Website: theresehuston.com

Twitter: https://twitter.com/ThereseHuston

Check out the full interview transcript

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How do you maximize health span and avoid the slow decline often associated with aging? Rudy Inaba, an expert in performance health and longevity, explains why data-driven fitness and personalized interventions are the future. He breaks down the importance of VO2 max as a predictor of longevity, the impact of structured exercise on metabolic health, and why the best path to aging well isn’t found in exotic supplements but in consistent, foundational habits. He also shares the latest advancements in medical technology, from musculoskeletal scans to plasmapheresis, offering insights into how science is reshaping the way we approach long-term health.

How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquiz

Thanks to Our Sponsors
Troscriptions — Precision, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code: AGEIST at checkout to save 10% on your order.

Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 10% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist.

LMNT Electrolytes — our number one electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. 

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Chapters

(00:14) Introduction to Cenegenics and Longevity Medicine

(03:22) Rudy Inaba's Journey and Background

(06:13) The Role of Data in Health Optimization

(09:02) The Importance of VO2 Max in Longevity

(12:13) Cenegenics: A Comprehensive Approach to Health

(15:08) The Evolution of Patient Care at Cenegenics

(18:01) The Pursuit of Optimal Health and Performance

(25:45) The Evolution of Health Awareness

(27:05) Exploring Plasmapheresis and Autoimmune Health

(29:45) Innovations in Longevity and Health Technologies

(34:10) The Importance of Multidisciplinary Approaches

(37:43) Holistic Health: Connecting the Dots

(41:25) Empowerment Through Small Choices

Key Moments
Exercise is the best thing we could put in a pill.

Every decision you make has the potential for a win.

If you want to improve longevity, start by improving your fitness—everything else follows.

Connect With Rudy and Cenegenics
Website: cenegenics.com

LinkedIn: linkedin.com/in/rudyinaba

Instagram: instagram.com/rudy.inaba

Check out the full interview transcript

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